Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 2
1985 1
1988 1
1989 1
1992 2
1993 2
1994 6
1995 1
1998 1
2001 1
2005 2
2006 1
2011 1
2017 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

23 results

Results by year

Filters applied: . Clear all
Page 1
The genotoxicity of 2-bromoacrolein and 2,3-dibromopropanal.
Gordon WP, Søderlund EJ, Holme JA, Nelson SD, Iyer L, Rivedal E, Dybing E. Gordon WP, et al. Carcinogenesis. 1985 May;6(5):705-9. doi: 10.1093/carcin/6.5.705. Carcinogenesis. 1985. PMID: 4006056
2-Bromoacrolein (2-BA) and 2,3-dibromopropanal (2,3-DBPA), an identified and a postulated reactive metabolite of tris(2,3-dibromopropyl)phosphate (Tris-BP), respectively, were found to cause mutations in Salmonella typhimurium TA 100 both in the absence and presence …
2-Bromoacrolein (2-BA) and 2,3-dibromopropanal (2,3-DBPA), an identified and a postulated reactive metabolite of tris(2,3-dibr …
Characterization of thymidine adducts formed by acrolein and 2-bromoacrolein.
Chenna A, Rieger RA, Iden CR. Chenna A, et al. Carcinogenesis. 1992 Dec;13(12):2361-5. doi: 10.1093/carcin/13.12.2361. Carcinogenesis. 1992. PMID: 1473245
Thymidine was permitted to react with the known mutagens acrolein and 2-bromoacrolein under physiological conditions. The products of these reactions were separated by HPLC and characterized by UV, FAB/MS, electrospray MS, 1H NMR and chemical transformation. ...Reac …
Thymidine was permitted to react with the known mutagens acrolein and 2-bromoacrolein under physiological conditions. The prod …
Characterization of 2'-deoxycytidine and 2'-deoxyuridine adducts formed in reactions with acrolein and 2-bromoacrolein.
Chenna A, Iden CR. Chenna A, et al. Chem Res Toxicol. 1993 May-Jun;6(3):261-8. doi: 10.1021/tx00033a003. Chem Res Toxicol. 1993. PMID: 8318647
The products of the reaction of the mutagenic aldehydes, acrolein and 2-bromoacrolein, with 2'-deoxycytidine and 2'-deoxyuridine have been determined. ...The N3-alkylated 2'-deoxyuridines were also synthesized by permitting 2'-deoxyuridine to react with 2- …
The products of the reaction of the mutagenic aldehydes, acrolein and 2-bromoacrolein, with 2'-deoxycytidine and 2'-deoxyuridi …
Detection and mechanism of formation of the potent direct-acting mutagen 2-bromoacrolein from 1,2-dibromo-3-chloropropane.
Omichinski JG, Soderlund EJ, Dybing E, Pearson PG, Nelson SD. Omichinski JG, et al. Toxicol Appl Pharmacol. 1988 Feb;92(2):286-94. doi: 10.1016/0041-008x(88)90388-2. Toxicol Appl Pharmacol. 1988. PMID: 3277317
Mutagenicity studies with selectively deuterated analogs showed that substitution of deuterium for hydrogen at C-1 or C-3 of DBCP modestly decreased mutagenicity, but that deuteration at both C-1 and C-3 markedly decreased mutagenicity. The formation rates of the potent direct-ac …
Mutagenicity studies with selectively deuterated analogs showed that substitution of deuterium for hydrogen at C-1 or C-3 of DBCP modestly d …
Formation of thymidine adducts and cross-linking potential of 2-bromoacrolein, a reactive metabolite of tris(2,3-dibromopropyl)phosphate.
van Beerendonk GJ, Nivard MJ, Vogel EW, Nelson SD, Meerman JH. van Beerendonk GJ, et al. Mutagenesis. 1992 Jan;7(1):19-24. doi: 10.1093/mutage/7.1.19. Mutagenesis. 1992. PMID: 1635451
DNA-adduct formation by the mutagen 2-bromoacrolein (2BA) with DNA was studied. [3-3H]2BA was reacted with single-stranded (ss) DNA or double-stranded (ds) DNA and subsequently incubated with methoxylamine to convert an unstable 2BA:thymidine adduct (Meerman et al., …
DNA-adduct formation by the mutagen 2-bromoacrolein (2BA) with DNA was studied. [3-3H]2BA was reacted with single-stranded (ss …
Activation mechanism of tris(2,3-dibromopropyl)phosphate to the potent mutagen, 2-bromoacrolein.
Nelson SD, Omichinski JG, Iyer L, Gordon WP, Soderlund EJ, Dybing E. Nelson SD, et al. Biochem Biophys Res Commun. 1984 May 31;121(1):213-9. doi: 10.1016/0006-291x(84)90709-5. Biochem Biophys Res Commun. 1984. PMID: 6375666
The potent mutagen 2- bromoacrolein is formed from the carcinogenic flame retardant tris(2,3-dibromopropyl)phosphate (Tris-BP) on incubation with hepatic microsomes. Substitution of deuterium for hydrogen at the terminal carbon atoms (C-3) of Tris-BP significantly d …
The potent mutagen 2- bromoacrolein is formed from the carcinogenic flame retardant tris(2,3-dibromopropyl)phosphate (Tris-BP) …
Lack of mammalian mutagenicity of the potent bacterial mutagen tris(2,3-dibromopropyl) phosphate and its metabolite 2-bromoacrolein.
van Beerendonk GJ, Klein JC, Tijdens RB, Lichtenauer-Kaligis EG, Tasseron-de Jong JG, Meerman JH. van Beerendonk GJ, et al. Mutat Res. 1998 Jul 31;415(3):201-11. doi: 10.1016/s1383-5718(98)00075-8. Mutat Res. 1998. PMID: 9714806
The flame retardant tris(2,3-dibromopropyl)phosphate (Tris-BP) and its metabolite 2-bromoacrolein (2BA) are very potent bacterial mutagens in Salmonella typhimurium (S. typhimurium) TA 100. ...
The flame retardant tris(2,3-dibromopropyl)phosphate (Tris-BP) and its metabolite 2-bromoacrolein (2BA) are very potent bacter …
Blocking of in vitro DNA replication by deoxycytidine adducts of the mutagen and clastogen 2-bromoacrolein.
van Beerendonk GJ, van Gog FB, Vrieling H, Pearson PG, Nelson SD, Meerman JH. van Beerendonk GJ, et al. Cancer Res. 1994 Feb 1;54(3):679-84. Cancer Res. 1994. PMID: 8306329
Calf thymus single-stranded DNA was modified with 2-bromoacrolein (2BA), a genotoxic metabolite of tris(2,3-dibromopropyl)phosphate. ...
Calf thymus single-stranded DNA was modified with 2-bromoacrolein (2BA), a genotoxic metabolite of tris(2,3-dibromopropyl)phos …
Formation of cyclic 1,N2-propanodeoxyguanosine and thymidine adducts in the reaction of the mutagen 2-bromoacrolein with calf thymus DNA.
Meerman JH, Smith TR, Pearson PG, Meier GP, Nelson SD. Meerman JH, et al. Cancer Res. 1989 Nov 15;49(22):6174-9. Cancer Res. 1989. PMID: 2478281
The interaction of the mutagen 2-bromoacrolein (2BA) with DNA and thymidine was studied in vitro by reaction of [3-3H]2BA with thymidine, RNA, single-stranded DNA, and double-stranded DNA in phosphate buffer (pH 7.4). ...
The interaction of the mutagen 2-bromoacrolein (2BA) with DNA and thymidine was studied in vitro by reaction of [3-3H]2BA with …
23 results