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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1959 1
1960 1
1964 1
1966 4
1967 2
1968 9
1969 55
1970 79
1971 172
1972 234
1973 326
1974 212
1975 256
1976 234
1977 212
1978 239
1979 284
1980 275
1981 293
1982 389
1983 352
1984 378
1985 378
1986 378
1987 419
1988 356
1989 407
1990 403
1991 385
1992 425
1993 447
1994 381
1995 453
1996 437
1997 371
1998 391
1999 392
2000 432
2001 459
2002 409
2003 440
2004 431
2005 509
2006 553
2007 595
2008 638
2009 598
2010 631
2011 699
2012 695
2013 761
2014 847
2015 801
2016 900
2017 909
2018 923
2019 1018
2020 1126
2021 1191
2022 1094
2023 1069
2024 363

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26,299 results

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Page 1
Trimethoprim: mechanisms of action, antimicrobial activity, bacterial resistance, pharmacokinetics, adverse reactions, and therapeutic indications.
Gleckman R, Blagg N, Joubert DW. Gleckman R, et al. Pharmacotherapy. 1981 Jul-Aug;1(1):14-20. doi: 10.1002/j.1875-9114.1981.tb03548.x. Pharmacotherapy. 1981. PMID: 6985448
Trimethoprim exerts antimicrobial activity by blocking the reduction of dihydrofolate to tetrahydrofolate, the active form of folic acid, by susceptible organisms. ...The safety of trimethoprim in the pregnant woman has not been established. Since indiscriminate use
Trimethoprim exerts antimicrobial activity by blocking the reduction of dihydrofolate to tetrahydrofolate, the active form of folic a
Trimethoprim-sulfamethoxazole.
Cockerill FR 3rd, Edson RS. Cockerill FR 3rd, et al. Mayo Clin Proc. 1987 Oct;62(10):921-9. doi: 10.1016/s0025-6196(12)65049-6. Mayo Clin Proc. 1987. PMID: 3498863
The antimicrobial combination of trimethoprim and sulfamethoxazole is active in vitro against a variety of gram-positive and gram-negative bacteria. ...When the creatinine clearance decreases to less than 30 ml/min, the dosage of trimethoprim-sulfamethoxazole should …
The antimicrobial combination of trimethoprim and sulfamethoxazole is active in vitro against a variety of gram-positive and gram-neg …
Trimethoprim.
[No authors listed] [No authors listed] Lancet. 1980 Mar 8;1(8167):519-20. Lancet. 1980. PMID: 6102239 No abstract available.
The comeback of trimethoprim in France.
Caron F, Wehrle V, Etienne M. Caron F, et al. Med Mal Infect. 2017 Jun;47(4):253-260. doi: 10.1016/j.medmal.2016.12.001. Epub 2017 Jan 2. Med Mal Infect. 2017. PMID: 28043762 Review.
Already used in various countries, trimethoprim (TMP) was withdrawn from the French market in 1990, but should be soon available again. ...
Already used in various countries, trimethoprim (TMP) was withdrawn from the French market in 1990, but should be soon available agai …
Trimethoprim-sulfamethoxazole.
Smith LG, Sensakovic J. Smith LG, et al. Med Clin North Am. 1982 Jan;66(1):143-56. doi: 10.1016/s0025-7125(16)31448-1. Med Clin North Am. 1982. PMID: 7038324 Review. No abstract available.
New analogs of trimethoprim.
Then RL, Böhni E, Angehrn P, Plozza-Nottebrock H, Stoeckel K. Then RL, et al. Rev Infect Dis. 1982 Mar-Apr;4(2):372-7. doi: 10.1093/clinids/4.2.372. Rev Infect Dis. 1982. PMID: 7051237 Review.
These analogs exhibit physicochemical properties different from those of trimethoprim and are potent inhibitors of several dihydrofolate reductases. Because they differ from trimethoprim in lipophilicity, their in vitro activity, spectrum of activity, and pharmacoki …
These analogs exhibit physicochemical properties different from those of trimethoprim and are potent inhibitors of several dihydrofol …
Trimethoprim-sulfamethoxazole for bacterial meningitis.
Levitz RE, Quintiliani R. Levitz RE, et al. Ann Intern Med. 1984 Jun;100(6):881-90. doi: 10.7326/0003-4819-100-6-881. Ann Intern Med. 1984. PMID: 6372565 Review.
Trimethoprim-sulfamethoxazole has excellent microbiologic activity against most pathogens that produce meningitis; both components of this drug have high penetration into tissues, including the cerebrospinal fluid. ...The success of trimethoprim-sulfamethoxazole in
Trimethoprim-sulfamethoxazole has excellent microbiologic activity against most pathogens that produce meningitis; both components of
Trimethoprim-sulphamethoxazole.
Choudhury P. Choudhury P. Indian Pediatr. 1987 Nov;24(11):1035-7. Indian Pediatr. 1987. PMID: 3502468 No abstract available.
Trimethoprim.
Rich G, Mee B. Rich G, et al. Med J Aust. 1985 Mar 18;142(6):350-2. doi: 10.5694/j.1326-5377.1985.tb113412.x. Med J Aust. 1985. PMID: 3871895 No abstract available.
Trimethoprim-sulfamethoxazole.
Hughes WT. Hughes WT. Pediatr Clin North Am. 1983 Feb;30(1):27-30. doi: 10.1016/s0031-3955(16)34317-6. Pediatr Clin North Am. 1983. PMID: 6600834 No abstract available.
26,299 results
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