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Page 1
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA.
Lanigan RS, Yamarik TA. Lanigan RS, et al. Int J Toxicol. 2002;21 Suppl 2:95-142. doi: 10.1080/10915810290096522. Int J Toxicol. 2002. PMID: 12396676 Review.
EDTA (ethylenediamine tetraacetic acid) and its salts are substituted diamines. ...Exposure to EDTA in cosmetic formulations that may be inhaled, however, was a concern. ...
EDTA (ethylenediamine tetraacetic acid) and its salts are substituted diamines. ...Exposure to EDTA in cosmetic formula
EDTA and Salts.
Cherian P, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Fiume M, Heldreth B. Cherian P, et al. Int J Toxicol. 2023 Dec;42(3_suppl):32S-36S. doi: 10.1177/10915818231204270. Epub 2023 Sep 29. Int J Toxicol. 2023. PMID: 37772606
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1998, along with updated information regarding product types and concentrations of use and confirmed that EDTA and certain salts are safe as cosmetic ingredi …
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1998, along with updated …
Tetrasodium EDTA for the prevention of urinary catheter infections and blockages.
Moore JV, Kim D, Irwin NJ, Rimer JD, McCoy CP. Moore JV, et al. RSC Adv. 2023 Jan 11;13(4):2202-2212. doi: 10.1039/d2ra06418a. eCollection 2023 Jan 11. RSC Adv. 2023. PMID: 36741142 Free PMC article.
The aim of this study was to investigate the antimicrobial and anti-encrustation activities of tetrasodium ethylenediaminetetraacetic acid (tEDTA) to evaluate its potential efficacy in preventing CAUTIs and catheter blockages. ...
The aim of this study was to investigate the antimicrobial and anti-encrustation activities of tetrasodium ethylenediaminetetraacetic …
The Efficacy of Tetrasodium EDTA on Biofilms.
Percival SL, Salisbury AM. Percival SL, et al. Adv Exp Med Biol. 2018;1057:101-110. doi: 10.1007/5584_2017_134. Adv Exp Med Biol. 2018. PMID: 29280095
The aim of this study was to assess the anti-biofilm capabilities of tetrasodium EDTA (t-EDTA) as a stand-alone liquid and when incorporated in low concentrations into wound dressing prototypes. ...In conclusion, these studies show that t-EDTA as a sta …
The aim of this study was to assess the anti-biofilm capabilities of tetrasodium EDTA (t-EDTA) as a stand-alone liquid …
Cytotoxic effects of alkaline tetrasodium EDTA irrigating solutions.
Solana C, Ferrer-Luque CM, Wang X, Baca P, Ruiz-Linares M, Cabrera T. Solana C, et al. J Oral Sci. 2020 Jun 23;62(3):285-287. doi: 10.2334/josnusd.19-0234. Epub 2020 May 31. J Oral Sci. 2020. PMID: 32475864 Free article.
The aim of this study is to determine the cytotoxic effects of tetrasodium ethylenediaminetetraacetic acid (EDTANa(4)) when used alone or when combined with sodium hypochlorite (NaOCl), with and without the addition of cetrimide (CTR). ...
The aim of this study is to determine the cytotoxic effects of tetrasodium ethylenediaminetetraacetic acid (EDTANa(4)) when us …
Use of tetrasodium EDTA acid for the treatment of intraluminal obstruction of subcutaneous ureteral bypass devices.
Duval V, Dunn M, Vachon C. Duval V, et al. J Feline Med Surg. 2022 Oct;24(10):e330-e337. doi: 10.1177/1098612X221107795. Epub 2022 Jun 28. J Feline Med Surg. 2022. PMID: 35762269 Free PMC article.
OBJECTIVES: The aim of this study was to evaluate the efficacy and tolerability of a 4% tetrasodium EDTA (tEDTA) infusion protocol in the subcutaneous ureteral bypass (SUB) devices of cats with intraluminal obstruction at a veterinary teaching hospital between July …
OBJECTIVES: The aim of this study was to evaluate the efficacy and tolerability of a 4% tetrasodium EDTA (tEDTA) infusion prot …
Synergistic activity of tetrasodium EDTA, ethanol and chlorhexidine hydrochloride against planktonic and biofilm cells of clinically relevant pathogens.
Sivaranjani M, Liu F, White AP. Sivaranjani M, et al. J Glob Antimicrob Resist. 2021 Mar;24:148-157. doi: 10.1016/j.jgar.2020.12.002. Epub 2020 Dec 28. J Glob Antimicrob Resist. 2021. PMID: 33383260 Free article.
Our study aimed to evaluate the broad-spectrum antimicrobial efficacy of tetrasodium EDTA, ethanol and chlorhexidine hydrochloride (HCl) alone and in combination against clinically relevant planktonic and biofilm cells of bacterial and fungal pathogens. METHODS: MIC …
Our study aimed to evaluate the broad-spectrum antimicrobial efficacy of tetrasodium EDTA, ethanol and chlorhexidine hydrochlo …
Tetrasodium EDTA Is Effective at Eradicating Biofilms Formed by Clinically Relevant Microorganisms from Patients' Central Venous Catheters.
Liu F, Hansra S, Crockford G, Köster W, Allan BJ, Blondeau JM, Lainesse C, White AP. Liu F, et al. mSphere. 2018 Nov 28;3(6):e00525-18. doi: 10.1128/mSphere.00525-18. mSphere. 2018. PMID: 30487154 Free PMC article.
In this study, we analyzed 210 bacterial and fungal isolates from colonized CVADs or human bloodstream infections from two hospitals geographically separated in the east and west of Canada and screened the isolates for biofilm formation in vitro Twenty isolates, representing 12 c …
In this study, we analyzed 210 bacterial and fungal isolates from colonized CVADs or human bloodstream infections from two hospitals geograp …
EDTA: An Antimicrobial and Antibiofilm Agent for Use in Wound Care.
Finnegan S, Percival SL. Finnegan S, et al. Adv Wound Care (New Rochelle). 2015 Jul 1;4(7):415-421. doi: 10.1089/wound.2014.0577. Adv Wound Care (New Rochelle). 2015. PMID: 26155384 Free PMC article. Review.
Despite this a number of antibiofilm formulations and technologies incorporating ethylenediaminetetraacetic acid (EDTA) have demonstrated efficacy on in vitro biofilms. The aim of this article is to critically review EDTA, in particular tetrasodium
Despite this a number of antibiofilm formulations and technologies incorporating ethylenediaminetetraacetic acid (EDTA) have d …
Tetrasodium EDTA as a novel central venous catheter lock solution against biofilm.
Percival SL, Kite P, Eastwood K, Murga R, Carr J, Arduino MJ, Donlan RM. Percival SL, et al. Infect Control Hosp Epidemiol. 2005 Jun;26(6):515-9. doi: 10.1086/502577. Infect Control Hosp Epidemiol. 2005. PMID: 16018425
Biofilm-associated organisms on the lumens of these catheters have reduced susceptibility to antimicrobial chemotherapy. This study tested the efficacy of tetrasodium EDTA as a catheter lock solution on biofilms of several clinically relevant microorganisms. ...CONC …
Biofilm-associated organisms on the lumens of these catheters have reduced susceptibility to antimicrobial chemotherapy. This study tested t …
93 results