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Table representation of search results timeline featuring number of search results per year.
| Year | Number of Results |
|---|---|
| 1981 | 1 |
| 1982 | 3 |
| 1983 | 1 |
| 1984 | 9 |
| 1985 | 10 |
| 1986 | 12 |
| 1987 | 40 |
| 1988 | 54 |
| 1989 | 58 |
| 1990 | 62 |
| 1991 | 70 |
| 1992 | 119 |
| 1993 | 105 |
| 1994 | 110 |
| 1995 | 104 |
| 1996 | 82 |
| 1997 | 113 |
| 1998 | 99 |
| 1999 | 98 |
| 2000 | 113 |
| 2001 | 121 |
| 2002 | 100 |
| 2003 | 136 |
| 2004 | 93 |
| 2005 | 108 |
| 2006 | 88 |
| 2007 | 84 |
| 2008 | 104 |
| 2009 | 94 |
| 2010 | 86 |
| 2011 | 93 |
| 2012 | 108 |
| 2013 | 94 |
| 2014 | 97 |
| 2015 | 109 |
| 2016 | 84 |
| 2017 | 83 |
| 2018 | 73 |
| 2019 | 82 |
| 2020 | 98 |
| 2021 | 99 |
| 2022 | 69 |
| 2023 | 73 |
| 2024 | 34 |
METHODS AND RESULTS: We randomly assigned 3164 patients with New York Heart Association class II to IV heart failure and an ejection fraction < or = 30% to double-blind treatment with either low doses (2.5 to 5.0 mg daily, n=1596) or high doses (32.5 to 35 mg daily, n=1568) of
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