Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 1
1982 7
1983 19
1984 21
1985 36
1986 30
1987 31
1988 36
1989 41
1990 46
1991 47
1992 31
1993 28
1994 32
1995 23
1996 17
1997 22
1998 13
1999 31
2000 16
2001 18
2002 11
2003 25
2004 14
2005 14
2006 28
2007 23
2008 18
2009 20
2010 21
2011 18
2012 27
2013 17
2014 18
2015 20
2016 18
2017 15
2018 13
2019 22
2020 16
2021 20
2022 12
2023 19
2024 7

Text availability

Article attribute

Article type

Publication date

Search Results

917 results

Results by year

Filters applied: . Clear all
Page 1
Swainsonine-containing plants and their relationship to endophytic fungi.
Cook D, Gardner DR, Pfister JA. Cook D, et al. J Agric Food Chem. 2014 Jul 30;62(30):7326-34. doi: 10.1021/jf501674r. Epub 2014 May 6. J Agric Food Chem. 2014. PMID: 24758700 Review.
Swainsonine is present in a number of plant species worldwide and causes severe toxicosis in livestock grazing these plants. ...This review focuses on the three plant families and the associated taxa that contain swainsonine; the fungi that produce swainsonine …
Swainsonine is present in a number of plant species worldwide and causes severe toxicosis in livestock grazing these plants. ...This …
The toxicology mechanism of endophytic fungus and swainsonine in locoweed.
Wu C, Han T, Lu H, Zhao B. Wu C, et al. Environ Toxicol Pharmacol. 2016 Oct;47:38-46. doi: 10.1016/j.etap.2016.08.018. Epub 2016 Aug 31. Environ Toxicol Pharmacol. 2016. PMID: 27606974 Review.
There are aliphaticnitro compounds, selenium, selenium compounds, and alkaloids in locoweed. The toxic component in locoweed has been identified as swainsonine, an indolizidine alkaloid. Swainsonine inhibits lysosomal a-mannosidase and mannosidase II, resulting in a …
There are aliphaticnitro compounds, selenium, selenium compounds, and alkaloids in locoweed. The toxic component in locoweed has been identi …
The Biosynthesis Pathway of Swainsonine, a New Anticancer Drug from Three Endophytic Fungi.
Ren Z, Song R, Wang S, Quan H, Yang L, Sun L, Zhao B, Lu H. Ren Z, et al. J Microbiol Biotechnol. 2017 Nov 28;27(11):1897-1906. doi: 10.4014/jmb.1709.09003. J Microbiol Biotechnol. 2017. PMID: 29092390 Free article. Review.
Swainsonine (SW) is the principal toxic ingredient of locoweed plants that causes locoism characterized by a disorder of the nervous system. ...This paper mainly summarizes the local and foreign literature published thus far on the swainsonine biosynthesis pathway, …
Swainsonine (SW) is the principal toxic ingredient of locoweed plants that causes locoism characterized by a disorder of the nervous …
Synthesis of (-)-swainsonine and (-)-8-epi-swainsonine by the addition of allenylmetals to chiral alpha,beta-alkoxy sulfinylimines.
Louvel J, Chemla F, Demont E, Ferreira F, Pérez-Luna A. Louvel J, et al. Org Lett. 2011 Dec 16;13(24):6452-5. doi: 10.1021/ol202747p. Epub 2011 Nov 14. Org Lett. 2011. PMID: 22082237
The asymmetric synthesis of (-)-swainsonine and (-)-8-epi-swainsonine is reported through the addition of either the allenylzinc or the allenyl lithio cyanocuprate reagents derived from [3-(methoxymethoxy)prop-1-ynyl]trimethylsilane to enantiopure alpha,beta-dialkox …
The asymmetric synthesis of (-)-swainsonine and (-)-8-epi-swainsonine is reported through the addition of either the allenylzi …
Swainsonine protects H9c2 cells against lipopolysaccharide-induced apoptosis and inflammatory injury via down-regulating miR-429.
Lv H, Zhang S, Hao X. Lv H, et al. Cell Cycle. 2020 Jan;19(2):207-217. doi: 10.1080/15384101.2019.1706902. Epub 2019 Dec 26. Cell Cycle. 2020. PMID: 31876239 Free PMC article. Updated.
Generally, 30% of PM patients will die or undergo heart transplantation. Swainsonine (SW) is a natural alkaloid and an anti-cancer substance. ...
Generally, 30% of PM patients will die or undergo heart transplantation. Swainsonine (SW) is a natural alkaloid and an anti-cancer su …
Swainsonine: a new antineoplastic immunomodulator.
Mohla S, Humphries MJ, White SL, Matsumoto K, Newton SA, Sampson CC, Bowen D, Olden K. Mohla S, et al. J Natl Med Assoc. 1989 Oct;81(10):1049-56. J Natl Med Assoc. 1989. PMID: 2509720 Free PMC article. Review.
Swainsonine, an indolizidine alkaloid with immunomodulatory activity, has been found to be effective in inhibiting metastatic dissemination and growth of primary tumors of both murine and human origins. The unique ability of swainsonine to exhibit antimetastatic, an …
Swainsonine, an indolizidine alkaloid with immunomodulatory activity, has been found to be effective in inhibiting metastatic dissemi …
Intoxication of llamas by Astragalus punae in Argentina.
Marin RE, Gardner DR, Armien AG, Fortunato RH, Uzal FA. Marin RE, et al. J Vet Diagn Invest. 2022 Jul;34(4):674-678. doi: 10.1177/10406387221094272. Epub 2022 May 6. J Vet Diagn Invest. 2022. PMID: 35524435 Free PMC article.
Several plants that contain indolizidine alkaloids, including swainsonine, are toxic to livestock, causing dysfunctional lysosomes and storage disease. ...Ultrastructurally, these changes consisted of severely dilated lysosomes. Swainsonine was detected in stem and …
Several plants that contain indolizidine alkaloids, including swainsonine, are toxic to livestock, causing dysfunctional lysosomes an …
Asymmetric synthesis of (-)-swainsonine, (+)-1,2-di-epi-swainsonine, and (+)-1,2,8-tri-epi-swainsonine.
Lindsay KB, Pyne SG. Lindsay KB, et al. J Org Chem. 2002 Nov 1;67(22):7774-80. doi: 10.1021/jo025977w. J Org Chem. 2002. PMID: 12398502
The asymmetric synthesis of (-)-swainsonine via a nonchiral pool route that involves the Sharpless epoxidation to induce chirality is reported. ...This synthetic strategy also allowed for the diastereoselective synthesis of (+)-1,2-di-epi-swainsonine and (+)-1,2,8-t …
The asymmetric synthesis of (-)-swainsonine via a nonchiral pool route that involves the Sharpless epoxidation to induce chirality is …
917 results