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123 results

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Page 1
Digestive enzymes and sphingomyelinase D in spiders without venom (Uloboridae).
Valladão R, Neto OBS, de Oliveira Gonzaga M, Pimenta DC, Lopes AR. Valladão R, et al. Sci Rep. 2023 Feb 15;13(1):2661. doi: 10.1038/s41598-023-29828-x. Sci Rep. 2023. PMID: 36792649 Free PMC article.
Even enzymes thought to be unique to venom, including enzymes such as sphingomyelinase D, were found in the digestive system of non-venomous spiders, suggesting a common origin between digestive enzymes and enzymes present in venoms. ...
Even enzymes thought to be unique to venom, including enzymes such as sphingomyelinase D, were found in the digestive system o …
Loxoscelism.
Swanson DL, Vetter RS. Swanson DL, et al. Clin Dermatol. 2006 May-Jun;24(3):213-21. doi: 10.1016/j.clindermatol.2005.11.006. Clin Dermatol. 2006. PMID: 16714202 Review.
Although Loxosceles bites are usually mild, they may ulcerate or cause more severe, systemic reactions. These injuries mostly are due to sphingomyelinase D in the spider venom. There is no proven effective therapy for Loxosceles bites, although many therapies are re …
Although Loxosceles bites are usually mild, they may ulcerate or cause more severe, systemic reactions. These injuries mostly are due to …
Sphingomyelinase D in sicariid spider venom is a potent insecticidal toxin.
Zobel-Thropp PA, Kerins AE, Binford GJ. Zobel-Thropp PA, et al. Toxicon. 2012 Sep 1;60(3):265-71. doi: 10.1016/j.toxicon.2012.04.350. Epub 2012 May 4. Toxicon. 2012. PMID: 22561243
Spider venoms have evolved over hundreds of millions of years with a primary role of immobilizing prey. Sphingomyelinase D (SMase D) and homologs in the SicTox gene family are the most abundantly expressed toxic protein in venoms of Loxosceles and Sicarius spiders ( …
Spider venoms have evolved over hundreds of millions of years with a primary role of immobilizing prey. Sphingomyelinase D (SM …
Loxosceles venom Sphingomyelinase D activates human blood leukocytes: Role of the complement system.
Manzoni-de-Almeida D, Squaiella-Baptistão CC, Lopes PH, van den Berg CW, Tambourgi DV. Manzoni-de-Almeida D, et al. Mol Immunol. 2018 Feb;94:45-53. doi: 10.1016/j.molimm.2017.12.009. Epub 2017 Dec 16. Mol Immunol. 2018. PMID: 29257998
Envenomation by Loxosceles spiders can result in severe systemic and local reactions, which are mainly triggered by Sphingomyelinase D (SMase D), a toxic component of Loxosceles venom. SMase D induces a systemic inflammatory condition similar to the reaction observe …
Envenomation by Loxosceles spiders can result in severe systemic and local reactions, which are mainly triggered by Sphingomyelinase …
Sphingomyelinase D activity in model membranes: structural effects of in situ generation of ceramide-1-phosphate.
Stock RP, Brewer J, Wagner K, Ramos-Cerrillo B, Duelund L, Jernshøj KD, Olsen LF, Bagatolli LA. Stock RP, et al. PLoS One. 2012;7(4):e36003. doi: 10.1371/journal.pone.0036003. Epub 2012 Apr 25. PLoS One. 2012. PMID: 22558302 Free PMC article.
The toxicity of Loxosceles spider venom has been attributed to a rare enzyme, sphingomyelinase D, which transforms sphingomyelin to ceramide-1-phosphate. ...In this work the effects of ceramide-1-phosphate on model membranes were studied both by in situ generation o …
The toxicity of Loxosceles spider venom has been attributed to a rare enzyme, sphingomyelinase D, which transforms sphingomyel …
123 results