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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1933 1
1934 1
1951 1
1952 1
1955 1
1957 2
1958 1
1959 1
1960 2
1963 3
1964 1
1965 1
1966 3
1967 3
1968 3
1970 6
1971 6
1972 3
1973 1
1974 8
1975 21
1976 13
1977 11
1978 15
1979 13
1980 17
1981 29
1982 23
1983 21
1984 17
1985 14
1986 20
1987 12
1988 19
1989 6
1990 13
1991 13
1992 17
1993 12
1994 12
1995 13
1996 18
1997 16
1998 12
1999 14
2000 14
2001 22
2002 29
2003 27
2004 24
2005 33
2006 31
2007 22
2008 37
2009 28
2010 39
2011 46
2012 52
2013 45
2014 40
2015 48
2016 55
2017 45
2018 51
2019 53
2020 71
2021 69
2022 74
2023 63
2024 22

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1,344 results

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Page 1
Pharmacological effects of harmine and its derivatives: a review.
Zhang L, Li D, Yu S. Zhang L, et al. Arch Pharm Res. 2020 Dec;43(12):1259-1275. doi: 10.1007/s12272-020-01283-6. Epub 2020 Nov 18. Arch Pharm Res. 2020. PMID: 33206346 Review.
Harmine derivatives exhibit pharmacological effects similar to those of harmine, but with better antitumor activity and low neurotoxicity. Many studies have been conducted on the pharmacological activities of harmine and harmine derivatives. This artic
Harmine derivatives exhibit pharmacological effects similar to those of harmine, but with better antitumor activity and low ne
Bioactive β-Carbolines in Food: A Review.
Piechowska P, Zawirska-Wojtasiak R, Mildner-Szkudlarz S. Piechowska P, et al. Nutrients. 2019 Apr 11;11(4):814. doi: 10.3390/nu11040814. Nutrients. 2019. PMID: 30978920 Free PMC article. Review.
Inhibition of DYRK1a Enhances Cardiomyocyte Cycling After Myocardial Infarction.
Young A, Bradley LA, Farrar E, Bilcheck HO, Tkachenko S, Saucerman JJ, Bekiranov S, Wolf MJ. Young A, et al. Circ Res. 2022 Apr 29;130(9):1345-1361. doi: 10.1161/CIRCRESAHA.121.320005. Epub 2022 Apr 4. Circ Res. 2022. PMID: 35369706 Free PMC article.
Harmine also increased cardiomyocyte cycling after I/R MI in alphaDKRC::RLTG mice, 10.81.5 versus 24.32.6 enhanced Green Fluorescent Protein (eGFP)+ cardiomyocytes, placebo versus harmine, respectively, P=1.010(-)(3). The effects of harmine on left ventricula
Harmine also increased cardiomyocyte cycling after I/R MI in alphaDKRC::RLTG mice, 10.81.5 versus 24.32.6 enhanced Green Fluorescent
Cell-based assays and molecular simulation reveal that the anti-cancer harmine is a specific matrix metalloproteinase-3 (MMP-3) inhibitor.
Chin LT, Liu KW, Chen YH, Hsu SC, Huang L. Chin LT, et al. Comput Biol Chem. 2021 Oct;94:107556. doi: 10.1016/j.compbiolchem.2021.107556. Epub 2021 Aug 6. Comput Biol Chem. 2021. PMID: 34384998
The biological activities of harmine have been a much clearer picture in recent years, which include anti-tumor, anti-inflammation and cytotoxic properties. ...These results showed that although harmine stimulation in vitro has very little or no effects on MMP-3 exp …
The biological activities of harmine have been a much clearer picture in recent years, which include anti-tumor, anti-inflammation an …
Metabolism of the beta-carbolines, harmine and harmol, by liver microsomes from phenobarbitone- or 3-methylcholanthrene-treated mice. Identification and quantitation of two novel harmine metabolites.
Tweedie DJ, Burke MD. Tweedie DJ, et al. Drug Metab Dispos. 1987 Jan-Feb;15(1):74-81. Drug Metab Dispos. 1987. PMID: 2881762
This study extends an investigation of the metabolism of the beta-carbolines, harmine and harmol, by untreated, phenobarbitone-induced, or 3-methylcholanthrene (MC)-induced mouse liver microsomes to identify two MC-inducible metabolites of harmine and to quantitate …
This study extends an investigation of the metabolism of the beta-carbolines, harmine and harmol, by untreated, phenobarbitone-induce …
Dietary inhibitors of monoamine oxidase A.
Dixon Clarke SE, Ramsay RR. Dixon Clarke SE, et al. J Neural Transm (Vienna). 2011 Jul;118(7):1031-41. doi: 10.1007/s00702-010-0537-x. Epub 2010 Dec 29. J Neural Transm (Vienna). 2011. PMID: 21190052 Review.
Harmane: an atypical neurotransmitter?
Abu Ghazaleh H, Lalies MD, Nutt DJ, Hudson AL. Abu Ghazaleh H, et al. Neurosci Lett. 2015 Mar 17;590:1-5. doi: 10.1016/j.neulet.2015.01.057. Epub 2015 Jan 24. Neurosci Lett. 2015. PMID: 25625221
β-Carboline (norharman).
Thatcher RJ, Douthwaite RE. Thatcher RJ, et al. Acta Crystallogr C. 2011 Jul;67(Pt 7):o241-3. doi: 10.1107/S0108270111021706. Epub 2011 Jun 23. Acta Crystallogr C. 2011. PMID: 21727633
Inhibition of DYRK1A attenuates vascular remodeling in pulmonary arterial hypertension via suppressing STAT3/Pim-1/NFAT pathway.
Lan C, Fang G, Qiu C, Li X, Yang F, Yang Y. Lan C, et al. Clin Exp Hypertens. 2024 Dec 31;46(1):2297642. doi: 10.1080/10641963.2023.2297642. Epub 2023 Dec 26. Clin Exp Hypertens. 2024. PMID: 38147409 Free article.
We found that DYRK1A was upregulated in PASMCs in response to hypoxia, both in vivo and in vitro. Inhibition of DYRK1A by harmine significantly attenuated hypoxia-induced pulmonary hypertension and pulmonary artery remodeling. Mechanistically, we found that DYRK1A promoted …
We found that DYRK1A was upregulated in PASMCs in response to hypoxia, both in vivo and in vitro. Inhibition of DYRK1A by harmine sig …
Harmine impairs memory performance of treated rats and nontreated cagemates.
Libânio TC, Eufrásio RA, Niigaki SS, Peres FF, Silva RH, Zuardi AW, Hallak JEC, Crippa JAS, Calzavara MB, Abílio VC. Libânio TC, et al. Exp Clin Psychopharmacol. 2022 Dec;30(6):751-759. doi: 10.1037/pha0000525. Epub 2021 Nov 4. Exp Clin Psychopharmacol. 2022. PMID: 34735205
Although Ayuahuasca-and consequently harmine-is usually consumed in rituals, the role of social contexts in the behavioral effects of harmine has not been investigated yet. ...The main results are: (a) harmine impaired CFC (10 mg/kg) and PMDAT discrimination …
Although Ayuahuasca-and consequently harmine-is usually consumed in rituals, the role of social contexts in the behavioral effects of …
1,344 results