9-**2-Phosphonylmethoxy*ethyl*guanine OR 114088-58-3 [rn] - Search Results

Year	Number of Results
1990	2
1992	2
1993	2
1997	3
1998	2
1999	5
2000	1
2006	2
2008	2
2009	2
2010	3
2011	2
2012	1
2013	1
2014	1
2015	1
2017	1
2022	1
2023	7
2024	0

1

In vivo antitumor activity of 9-[(2-phosphonylmethoxy)ethyl]-guanine and related phosphonate nucleotide analogues.

Rose WC, Crosswell AR, Bronson JJ, Martin JC. Rose WC, et al. J Natl Cancer Inst. 1990 Mar 21;82(6):510-2. doi: 10.1093/jnci/82.6.510. J Natl Cancer Inst. 1990. PMID: 2313724

Three compounds, (S)-9-[(3-hydroxy-2-phosphonylmethoxy)propyl]adenine (HPMPA), 9-[(2-phosphonylmethoxy)ethyl]adenine (PMEA), and 9-[(2-phosphonylmethoxy)ethyl]guanine (PMEG) were modestly active with treated versus control (T/C) values of 125%-1 …

Three compounds, (S)-9-[(3-hydroxy-2-phosphonylmethoxy)propyl]adenine (HPMPA), 9-[(2-phosphonylmethoxy)ethyl]adenine (PMEA), and 9-[( …

2

A novel lipid prodrug strategy for sustained delivery of hexadecyloxypropyl 9-[2-(phosphonomethoxy)ethyl]guanine (HDP-PMEG) on unwanted ocular proliferation.

Chen M, Hou J, Tan G, Xie P, Freeman WR, Beadle JR, Hostetler KY, Cheng L. Chen M, et al. Drug Deliv. 2017 Nov;24(1):1703-1712. doi: 10.1080/10717544.2017.1399303. Drug Deliv. 2017. PMID: 29115885 Free PMC article.

3

Treatment of latent rabbit and human papillomavirus infections with 9-(2-phosphonylmethoxy)ethylguanine (PMEG).

Kreider JW, Balogh K, Olson RO, Martin JC. Kreider JW, et al. Antiviral Res. 1990 Jul;14(1):51-8. doi: 10.1016/0166-3542(90)90065-f. Antiviral Res. 1990. PMID: 1964372

4

9-(2-Phosphonylmethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cpr-PMEDAP) as a prodrug of 9-(2-phosphonylmethoxyethyl)guanine (PMEG).

Compton ML, Toole JJ, Paborsky LR. Compton ML, et al. Biochem Pharmacol. 1999 Aug 15;58(4):709-14. doi: 10.1016/s0006-2952(99)00138-0. Biochem Pharmacol. 1999. PMID: 10413310

5

Antiproliferative property of hexadecyloxypropyl 9-[2-(phosphonomethoxy) ethyl] guanine (HDP-PMEG) for unwanted ocular proliferation.

Hou J, Li Y, Zhou Z, Valiaeva N, Beadle JR, Hostetler K, Freeman WR, Hu DN, Chen H, Cheng L. Hou J, et al. Mol Vis. 2011 Mar 2;17:627-37. Mol Vis. 2011. PMID: 21386925 Free PMC article.

6

Antiproliferative effects of octadecyloxyethyl 9-[2-(phosphonomethoxy)ethyl]guanine against Me-180 human cervical cancer cells in vitro and in vivo.

Valiaeva N, Trahan J, Aldern KA, Beadle JR, Hostetler KY. Valiaeva N, et al. Chemotherapy. 2010;56(1):54-9. doi: 10.1159/000292582. Epub 2010 Mar 8. Chemotherapy. 2010. PMID: 20215748 Free PMC article.

7

Synthesis and antiviral activity of 2'-substituted 9-[2-(phosphonomethoxy)ethyl]guanine analogues.

Yu KL, Bronson JJ, Yang H, Patick A, Alam M, Brankovan V, Datema R, Hitchcock MJ, Martin JC. Yu KL, et al. J Med Chem. 1993 Sep 17;36(19):2726-38. doi: 10.1021/jm00071a003. J Med Chem. 1993. PMID: 8410987

8

Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newborn NMRI mice.

Balzarini J, Vahlenkamp T, Egberink H, Hartmann K, Witvrouw M, Pannecouque C, Casara P, Navé JF, De Clercq E. Balzarini J, et al. Antimicrob Agents Chemother. 1997 Mar;41(3):611-6. doi: 10.1128/AAC.41.3.611. Antimicrob Agents Chemother. 1997. PMID: 9056002 Free PMC article.

9

Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine.

Yu KL, Bronson JJ, Yang H, Patick A, Alam M, Brankovan V, Datema R, Hitchcock MJ, Martin JC. Yu KL, et al. J Med Chem. 1992 Aug 7;35(16):2958-69. doi: 10.1021/jm00094a005. J Med Chem. 1992. PMID: 1323678

10

9-(2-phosphonylmethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine: a novel prodrug of 9-(2-phosphonylmethoxyethyl)guanine with improved antitumor efficacy and selectivity in choriocarcinoma-bearing rats.

Naesens L, Hatse S, Segers C, Verbeken E, De Clercq E, Waer M, Balzarini J. Naesens L, et al. Oncol Res. 1999;11(4):195-203. Oncol Res. 1999. PMID: 10566618

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