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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1799 1
1801 1
1806 1
1808 1
1814 1
1817 1
1828 1
1832 1
1840 1
1841 2
1846 1
1855 1
1857 1
1860 2
1865 1
1866 1
1867 3
1868 1
1869 2
1870 1
1871 3
1872 2
1873 6
1874 1
1875 1
1877 2
1878 1
1880 3
1881 4
1883 2
1884 3
1885 1
1887 5
1888 2
1889 1
1890 3
1891 4
1892 2
1893 3
1894 5
1895 2
1896 2
1897 3
1898 5
1899 6
1900 1
1901 2
1902 1
1904 2
1906 2
1907 4
1908 6
1909 4
1910 2
1911 14
1912 42
1913 6
1914 1
1915 4
1916 2
1917 6
1918 5
1919 2
1920 4
1921 17
1922 4
1923 5
1924 7
1925 35
1926 17
1927 5
1928 3
1929 8
1930 13
1931 3
1932 1
1933 3
1934 3
1935 2
1936 4
1937 4
1938 5
1939 7
1940 3
1941 5
1942 6
1943 6
1944 3
1945 27
1946 105
1947 144
1948 166
1949 83
1950 88
1951 180
1952 168
1953 230
1954 278
1955 322
1956 178
1957 338
1958 261
1959 146
1960 117
1961 105
1962 134
1963 225
1964 311
1965 307
1966 302
1967 353
1968 301
1969 363
1970 374
1971 355
1972 493
1973 467
1974 716
1975 1708
1976 1489
1977 1675
1978 1601
1979 1994
1980 1663
1981 1941
1982 2239
1983 2576
1984 2961
1985 3052
1986 3345
1987 3856
1988 4220
1989 5189
1990 5324
1991 5671
1992 6339
1993 6851
1994 7321
1995 7272
1996 6872
1997 6968
1998 7263
1999 7491
2000 8138
2001 8317
2002 9311
2003 9451
2004 10499
2005 11154
2006 11749
2007 12090
2008 13312
2009 14014
2010 15208
2011 15407
2012 15486
2013 16121
2014 16743
2015 17053
2016 16928
2017 17135
2018 18048
2019 18931
2020 21037
2021 21955
2022 21491
2023 21202
2024 7462

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437,288 results

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The following terms were ignored: [, ]
The following terms were not found in PubMed: 7-allylbenzo, dioxepin-3-one
Unknown fields were ignored: [b]
Page 1
Busulfan.
[No authors listed] [No authors listed] 2021 Aug 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Aug 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000295 Free Books & Documents. Review.
Hydroquinone.
[No authors listed] [No authors listed] 2019 Feb 7. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2019 Feb 7. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999728 Free Books & Documents. Review.
Production of 21-hydroxy-20-methyl-pregna-1,4-dien-3-one by modifying multiple genes in Mycolicibacterium.
Yuan C, Ma Z, Li Y, Zhang J, Liu X, Han S, Du G, Shi J, Sun J, Zhang B. Yuan C, et al. Appl Microbiol Biotechnol. 2023 Mar;107(5-6):1563-1574. doi: 10.1007/s00253-023-12399-2. Epub 2023 Feb 2. Appl Microbiol Biotechnol. 2023. PMID: 36729227
Nevertheless, the production of 1,4-HP remains unsatisfactory. In this study, an ideal 1,4-HP producing strain was constructed. ...Consequently, the yield of 1,4-HP achieved 10.5 g/L. The molar yield and the purity of 1,4-HP …
Nevertheless, the production of 1,4-HP remains unsatisfactory. In this study, an ideal 1,4-HP producing strain w …
IP3 Receptor Plasticity Underlying Diverse Functions.
Hamada K, Mikoshiba K. Hamada K, et al. Annu Rev Physiol. 2020 Feb 10;82:151-176. doi: 10.1146/annurev-physiol-021119-034433. Epub 2019 Nov 15. Annu Rev Physiol. 2020. PMID: 31730387 Review.
In the body, extracellular stimuli produce inositol 1,4,5-trisphosphate (IP(3)), an intracellular chemical signal that binds to the IP(3) receptor (IP(3)R) to release calcium ions (Ca(2+)) from the endoplasmic reticulum. ...
In the body, extracellular stimuli produce inositol 1,4,5-trisphosphate (IP(3)), an intracellular chemical signal that binds t …
Chemoselective reduction of 1,4,6-cholestatrien-3-one and 1,4,6-androstatriene-3,17-dione by various hydride reagents.
Kim E, Ma E. Kim E, et al. Steroids. 2007 Apr;72(4):360-7. doi: 10.1016/j.steroids.2006.12.008. Epub 2007 Jan 10. Steroids. 2007. PMID: 17303200
Cholesterol (cholest-5-en-3beta-ol) and dehydroepiandrosterone (DHEA) were oxidized with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone to form 1,4,6-cholestatrien-3-one and 1,4,6-androstatriene-3,17-dione. ...Reaction of LiAlH(4) (6 equiv.) f …
Cholesterol (cholest-5-en-3beta-ol) and dehydroepiandrosterone (DHEA) were oxidized with 2,3-dichloro-5,6-dicyano-1,4-benzoqui …
Advances in bioremediation of 1,4-dioxane-contaminated waters.
Zhang S, Gedalanga PB, Mahendra S. Zhang S, et al. J Environ Manage. 2017 Dec 15;204(Pt 2):765-774. doi: 10.1016/j.jenvman.2017.05.033. Epub 2017 Jun 16. J Environ Manage. 2017. PMID: 28625566 Review.
1,4-Dioxane is a contaminant of emerging concern that has been found widespread in groundwater, surface water, and drinking water environments. Many states are implementing lower regulatory advisory levels based on the toxicological profile of 1,4-diox …
1,4-Dioxane is a contaminant of emerging concern that has been found widespread in groundwater, surface water, and drinking wa …
Dithieno[1,4]thiazines and Bis[1]benzothieno[1,4]thiazines-Organometallic Synthesis and Functionalization of Electron Density Enriched Congeners of Phenothiazine.
May L, Müller TJJ. May L, et al. Molecules. 2020 May 7;25(9):2180. doi: 10.3390/molecules25092180. Molecules. 2020. PMID: 32392728 Free PMC article. Review.
This mini-review summarizes the syntheses and functionalizations of dithieno[1,4]thiazines and bis[1]benzothieno[1,4]thiazines, both electron density-enriched congeners of phenothiazines with remarkable electronic properties. ...The tunable photophysic …
This mini-review summarizes the syntheses and functionalizations of dithieno[1,4]thiazines and bis[1]benzothieno[1,4 …
Stereocontrolled total synthesis of iminosugar 1,4-dideoxy-1,4-imino-D-iditol.
De Angelis M, Primitivo L, Lucarini C, Agostinelli S, Sappino C, Ricelli A, Righi G. De Angelis M, et al. Carbohydr Res. 2020 Jun;492:108028. doi: 10.1016/j.carres.2020.108028. Epub 2020 May 1. Carbohydr Res. 2020. PMID: 32413728
The first stereocontrolled total synthesis of iminosugar 1,4-dideoxy-1,4-imino-D-iditol is described. The key step in our approach was the double diastereoselection in the asymmetric dihydroxylation (AD) of suitable optically active olefin, the chiral …
The first stereocontrolled total synthesis of iminosugar 1,4-dideoxy-1,4-imino-D-iditol is described. The key st …
Chemoselective [2 + 2]/[3 + 2] Photocycloaddition of 1,4-Dihydropyridines: Experimental and Theoretical Investigation.
Zhang X, Song X, Shi J, Yan H, Tian N. Zhang X, et al. J Org Chem. 2023 Jul 7;88(13):9066-9076. doi: 10.1021/acs.joc.3c00737. Epub 2023 Jun 12. J Org Chem. 2023. PMID: 37305905
The photocycloaddition of 1,4-dihydropyridines (1,4-DHPs) is a main approach to synthesize structurally complex compounds, which are important intermediates for the preparation of cage compounds, such as 3,9-diazatetraasterane, 3,6-diazatetraasterane, …
The photocycloaddition of 1,4-dihydropyridines (1,4-DHPs) is a main approach to synthesize structurally complex …
An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents.
Lafranconi M, Anderson J, Budinsky R, Corey L, Forsberg N, Klapacz J, LeBaron MJ. Lafranconi M, et al. Regul Toxicol Pharmacol. 2023 Aug;142:105428. doi: 10.1016/j.yrtph.2023.105428. Epub 2023 Jun 3. Regul Toxicol Pharmacol. 2023. PMID: 37277058 Free article. Review.
Importantly, these events occur at doses that exceed the metabolic clearance of absorbed 1,4-dioxane in rats and mice resulting in elevated systemic levels of parent 1,4-dioxane. Consistent with previous reviews, we found no evidence of direct mutageni …
Importantly, these events occur at doses that exceed the metabolic clearance of absorbed 1,4-dioxane in rats and mice resultin …
437,288 results
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