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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1947 2
1948 1
1950 2
1952 4
1953 1
1954 1
1955 2
1956 4
1957 8
1958 4
1959 9
1960 5
1961 16
1962 23
1963 84
1964 182
1965 148
1966 163
1967 171
1968 171
1969 171
1970 154
1971 170
1972 162
1973 203
1974 177
1975 150
1976 108
1977 101
1978 84
1979 100
1980 93
1981 92
1982 72
1983 88
1984 112
1985 97
1986 92
1987 100
1988 102
1989 131
1990 119
1991 112
1992 125
1993 124
1994 83
1995 72
1996 78
1997 74
1998 68
1999 69
2000 71
2001 65
2002 62
2003 80
2004 73
2005 62
2006 81
2007 76
2008 72
2009 62
2010 73
2011 80
2012 75
2013 85
2014 66
2015 82
2016 84
2017 68
2018 69
2019 72
2020 65
2021 69
2022 73
2023 52
2024 18

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6,048 results

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Page 1
Virtual screening of carboxylic acid reductases for biocatalytic synthesis of 6-aminocaproic acid and 1,6-hexamethylenediamine.
Shi K, Li JM, Zhang ZJ, Chen Q, Xu JH, Yu HL. Shi K, et al. Biotechnol Bioeng. 2023 Jul;120(7):1773-1783. doi: 10.1002/bit.28408. Epub 2023 May 2. Biotechnol Bioeng. 2023. PMID: 37130074
The key precursors for nylon synthesis, that is, 6-aminocaproic acid (6-ACA) and 1,6-hexamethylenediamine (HMD), are produced from petroleum-based feedstocks. A sustainable biocatalytic alternative method from bio-based adipic acid has been demonstrate …
The key precursors for nylon synthesis, that is, 6-aminocaproic acid (6-ACA) and 1,6-hexamethylenediamine (HMD), are pr …
Epsilon-aminocaproic acid (EACA).
Griffin JD, Ellman L. Griffin JD, et al. Semin Thromb Hemost. 1978 Summer;5(1):27-40. doi: 10.1055/s-0028-1087143. Semin Thromb Hemost. 1978. PMID: 568312
Epsilon-aminocaproic acid (EACA) is a synthetic inhibitor of the plasmin-plasminogen system. ...
Epsilon-aminocaproic acid (EACA) is a synthetic inhibitor of the plasmin-plasminogen system. ...
1,2,3-Triazole Derivatives as Novel Antifibrinolytic Drugs.
Bosch-Sanz O, Rabadà Y, Biarnés X, Pedreño J, Caveda L, Balcells M, Martorell J, Sánchez-García D. Bosch-Sanz O, et al. Int J Mol Sci. 2022 Nov 29;23(23):14942. doi: 10.3390/ijms232314942. Int J Mol Sci. 2022. PMID: 36499270 Free PMC article.
However, excessive fibrinolytic activity can lead to complications in different circumstances, such as general surgery or severe trauma. The current antifibrinolytic drugs in the market, aminocaproic acid (EACA) and tranexamic acid (TXA), require high doses r …
However, excessive fibrinolytic activity can lead to complications in different circumstances, such as general surgery or severe trauma. The …
Aminocaproic Acid and Tranexamic Acid Fail to Reverse Dabigatran-Induced Coagulopathy.
Levine M, Huang M, Henderson SO, Carmelli G, Thomas SH. Levine M, et al. Am J Ther. 2016 Nov/Dec;23(6):e1619-e1622. doi: 10.1097/MJT.0000000000000216. Am J Ther. 2016. PMID: 26241703
Neither tranexamic acid nor aminocaproic acid successfully reversed dabigatran-induced coagulopathy. In this rodent model of dabigatran-induced coagulopathy, neither tranexamic acid nor aminocaproic acid were able to reverse the coagulopa …
Neither tranexamic acid nor aminocaproic acid successfully reversed dabigatran-induced coagulopathy. In this rodent mod …
Antifibrinolytics in cardiac surgery.
Dhir A. Dhir A. Ann Card Anaesth. 2013 Apr-Jun;16(2):117-25. doi: 10.4103/0971-9784.109749. Ann Card Anaesth. 2013. PMID: 23545866 Review.
Since the withdrawal of aprotinin from the world market, the choice of antifibrinolytic agents has been limited to lysine analogues either tranexamic acid (TA) or epsilon amino caproic acid (EACA). While proponents of aprotinin still argue against its non-availabili …
Since the withdrawal of aprotinin from the world market, the choice of antifibrinolytic agents has been limited to lysine analogues either t …
CURRENT PROBLEMS IN HEMOSTASIS.
TOCANTINS LM, REID WO, SILVER MJ, KAZAL LA. TOCANTINS LM, et al. Ann N Y Acad Sci. 1964 Jul 9;115:21-30. doi: 10.1111/j.1749-6632.1964.tb50647.x. Ann N Y Acad Sci. 1964. PMID: 14196071 Review. No abstract available.
Benzofurazan -based fluorophore for the spectrofluorimetric determination of 6-Aminocaproic acid: Application to spiked human plasma and urine.
Anwer EF, Nour El-Deen DAM, Derayea SM, Omar MA. Anwer EF, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Mar 5;268:120723. doi: 10.1016/j.saa.2021.120723. Epub 2021 Dec 9. Spectrochim Acta A Mol Biomol Spectrosc. 2022. PMID: 34915229
The nucleophilic substitution interaction between the primary amine of 6-aminocaproic acid with 4-chloro-7-nitro benzofurazan (NBD-Cl) generated a yellow product. ...Moreover, the proposed method was extended to determine 6-aminocaproic acid …
The nucleophilic substitution interaction between the primary amine of 6-aminocaproic acid with 4-chloro-7-nitro benzof …
Natural and synthetic antifibrinolytics in cardiac surgery.
Hardy JF, Desroches J. Hardy JF, et al. Can J Anaesth. 1992 Apr;39(4):353-65. doi: 10.1007/BF03009046. Can J Anaesth. 1992. PMID: 1373346 Review.
The predominant haemostatic defect induced by CPB and, therefore, the mechanisms by which natural (aprotinin) or synthetic antifibrinolytics (sigma-amino-caproic acid, tranexamic acid) exert their effects have been difficult to define. ...Pending availability of the …
The predominant haemostatic defect induced by CPB and, therefore, the mechanisms by which natural (aprotinin) or synthetic antifibrinolytics …
One-pot synthesis of 6-aminohexanoic acid from cyclohexane using mixed-species cultures.
Bretschneider L, Wegner M, Bühler K, Bühler B, Karande R. Bretschneider L, et al. Microb Biotechnol. 2021 May;14(3):1011-1025. doi: 10.1111/1751-7915.13744. Epub 2020 Dec 28. Microb Biotechnol. 2021. PMID: 33369139 Free PMC article.
6-Aminohexanoic acid (6AHA) is a vital polymer building block for Nylon 6 production and an FDA-approved orphan drug. ...Thereby, Pseudomonas taiwanensis VLB120 strains harbouring an upstream cascade converting cyclohexane to either -caprolactone (-CL) or 6-hydroxyhexanoic …
6-Aminohexanoic acid (6AHA) is a vital polymer building block for Nylon 6 production and an FDA-approved orphan drug. ...Thereby, Pse …
6,048 results