Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1976 1
1978 1
1979 1
1982 3
1983 1
1984 3
1985 2
1986 1
1987 1
1988 2
1989 1
1991 1
1992 5
1993 6
1994 4
1995 1
1996 3
1997 4
1998 8
1999 7
2000 6
2001 14
2002 10
2003 20
2004 7
2005 10
2006 12
2007 11
2008 12
2009 10
2010 8
2011 6
2012 13
2013 16
2014 13
2015 11
2016 14
2017 11
2018 11
2019 16
2020 22
2021 23
2022 9
2023 15
2024 8

Text availability

Article attribute

Article type

Publication date

Search Results

334 results

Results by year

Filters applied: . Clear all
The following term was not found in PubMed: 5-methyl-2-octyl-3
Page 1
Natural 4-hydroxy-2,5-dimethyl-3(2H)-furanone (Furaneol).
Schwab W. Schwab W. Molecules. 2013 Jun 13;18(6):6936-51. doi: 10.3390/molecules18066936. Molecules. 2013. PMID: 23765232 Free PMC article. Review.
4-Hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF, furaneol) and its methyl ether 2,5-dimethyl-4-methoxy-3(2H)-furanone (DMMF) are import aroma chemicals and are considered key flavor compounds in many fruit. ...
4-Hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF, furaneol) and its methyl ether 2,5-dimethyl-4-methoxy-3(2H)-furanone …
Screening and Remodeling of Enone Oxidoreductase for High Production of 2(or 5)-Ethyl-5(or 2)-methyl-4-hydroxy-3(2H)-Furanone in Saccharomyces Cerevisiae.
Fu X, Hong K, Wang H, Zhang C, Lu W. Fu X, et al. J Agric Food Chem. 2022 Aug 17;70(32):9888-9897. doi: 10.1021/acs.jafc.2c03306. Epub 2022 Aug 4. J Agric Food Chem. 2022. PMID: 35925879
Owing to its unique fragrance, 4-hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (HEMF) is widely used as a food flavoring agent and has high demand. ...
Owing to its unique fragrance, 4-hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (HEMF) is widely used as a food flavoring …
A glucosyltransferase specific for 4-hydroxy-2,5-dimethyl-3(2H)-furanone in strawberry.
Yamada A, Ishiuchi K, Makino T, Mizukami H, Terasaka K. Yamada A, et al. Biosci Biotechnol Biochem. 2018 Sep 29:1-8. doi: 10.1080/09168451.2018.1524706. Online ahead of print. Biosci Biotechnol Biochem. 2018. PMID: 30269657
4-Hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) is a key aroma compound in Fragaria ananassa (strawberry). ...These results suggest that UGT85K16 might be UDP-glucose: HDMF glucosyltransferase in strawberries. ABBREVIATIONS: DMMF: 2,5-dimethyl-4-methoxy-3(2H)- …
4-Hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) is a key aroma compound in Fragaria ananassa (strawberry). ...These results sugge …
2,5-Dimethyl-4-hydroxy-3(2H)-furanone as an Anti-biofilm Agent Against Non-Candida albicans Candida Species.
Devadas SM, Nayak UY, Narayan R, Hande MH, Ballal M. Devadas SM, et al. Mycopathologia. 2019 Jun;184(3):403-411. doi: 10.1007/s11046-019-00341-y. Epub 2019 Jun 11. Mycopathologia. 2019. PMID: 31187338
METHODS: The present study investigated the modulatory effect of 2,5-dimethyl-4-hydroxy-3(2H)-furanone (DMHF) on NCAC biofilm formation and also assessed the effect of the DMHF-coated catheters on biofilm formation of NCAC. ...The excellent biological performance, c …
METHODS: The present study investigated the modulatory effect of 2,5-dimethyl-4-hydroxy-3(2H)-furanone (DMHF) on NCAC biofilm …
Identification and characterization of an enzyme involved in the biosynthesis of the 4-hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone in yeast.
Uehara K, Watanabe J, Mogi Y, Tsukioka Y. Uehara K, et al. J Biosci Bioeng. 2017 Mar;123(3):333-341. doi: 10.1016/j.jbiosc.2016.10.004. Epub 2016 Nov 16. J Biosci Bioeng. 2017. PMID: 27865643
4-Hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (HEMF) is considered a key flavor compound in soy sauce. ...Detailed analyses of an intermediate in the enzymatic reaction mixture revealed that HEMF is synthesized from (2E)-2-ethylidene-4-hydroxy-5-methyl-3( …
4-Hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (HEMF) is considered a key flavor compound in soy sauce. ...Detailed ana …
RIFM fragrance ingredient safety assessment, 3(2H)-furanone, 5-ethyl-4-hydroxy-2-methyl-, CAS Registry Number 27538-09-6.
Api AM, Belsito D, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Cancellieri MA, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Jones L, Joshi K, Kumar M, Lapczynski A, Lavelle M, Lee I, Liebler DC, Moustakas H, Na M, Penning TM, Ritacco G, Romine J, Sadekar N, Schultz TW, Selechnik D, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y. Api AM, et al. Food Chem Toxicol. 2022 Jan 15;159 Suppl 1:112646. doi: 10.1016/j.fct.2021.112646. Epub 2021 Oct 29. Food Chem Toxicol. 2022. PMID: 34756965 No abstract available.
Glucosylation of 4-Hydroxy-2,5-Dimethyl-3(2H)-Furanone, the Key Strawberry Flavor Compound in Strawberry Fruit.
Song C, Hong X, Zhao S, Liu J, Schulenburg K, Huang FC, Franz-Oberdorf K, Schwab W. Song C, et al. Plant Physiol. 2016 May;171(1):139-51. doi: 10.1104/pp.16.00226. Epub 2016 Mar 18. Plant Physiol. 2016. PMID: 26993618 Free PMC article.
Strawberries emit hundreds of different volatiles, but only a dozen, including the key compound HDMF [4-hydroxy-2,5-dimethyl-3(2H)-furanone] contribute to the flavor of the fruit. However, during ripening, a considerable amount of HDMF is metabolized to the flavorle …
Strawberries emit hundreds of different volatiles, but only a dozen, including the key compound HDMF [4-hydroxy-2,5-dimethyl-3(2H)- …
DMHF (2,5-dimethyl-4-hydroxy-3(2H)-furanone), a volatile food component with attractive sensory properties, brings physiological functions through inhalation.
Arihara K, Yokoyama I, Ohata M. Arihara K, et al. Adv Food Nutr Res. 2019;89:239-258. doi: 10.1016/bs.afnr.2019.05.001. Epub 2019 May 27. Adv Food Nutr Res. 2019. PMID: 31351527 Review.
2,5-Dimethyl-4-hydroxy-3(2H)-furanone (DMHF) is an aroma compound found in various foods, and used widely in the flavor and perfume industry. ...
2,5-Dimethyl-4-hydroxy-3(2H)-furanone (DMHF) is an aroma compound found in various foods, and used widely in the flavor and pe …
Reinvestigation of the reaction between 2-furancarboxaldehyde and 4-hydroxy-5-methyl-3(2H)-furanone.
Ravagli A, Boschin G, Scaglioni L, Arnoldi A. Ravagli A, et al. J Agric Food Chem. 1999 Dec;47(12):4962-9. doi: 10.1021/jf990523u. J Agric Food Chem. 1999. PMID: 10606559
In acetic acid/piperidine, besides 2-(2-furanylmethylene)-4-hydroxy-5-methyl-3(2H)-furanone (1) and 5-[2-(2-furanyl)ethenyl]-2-(2-furanylmethylene)-4-hydroxy-5-methyl -3( 2H)-furanone (2), four novel compounds, 15a, 15b, 16a, and 16b, were isolated and …
In acetic acid/piperidine, besides 2-(2-furanylmethylene)-4-hydroxy-5-methyl-3(2H)-furanone (1) and 5-[2-(2-furanyl)ethenyl]-2 …
Browning of Maillard reaction systems containing xylose and 4-hydroxy-5-methyl-3(2H)-furanone.
Nakamura M, Mikami Y, Noda K, Murata M. Nakamura M, et al. Biosci Biotechnol Biochem. 2021 Feb 18;85(2):401-410. doi: 10.1093/bbb/zbaa019. Biosci Biotechnol Biochem. 2021. PMID: 33604624
During research on the Maillard reaction between xylose (Xyl) and lysine (Lys), we detected 4-hydroxy-5-methyl-3(2H)-furanone (HMFO) as a major decomposition product of Xyl. To clarify the chemical pathway of the browning of pentose system, the formation and decompo …
During research on the Maillard reaction between xylose (Xyl) and lysine (Lys), we detected 4-hydroxy-5-methyl-3(2H)-furanone …
334 results