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Induction of synthesis of tetrahydropyrimidine derivatives in Streptomyces strains and their effect on Escherichia coli in response to osmotic and heat stress.
Malin G, Lapidot A. Malin G, et al. J Bacteriol. 1996 Jan;178(2):385-95. doi: 10.1128/jb.178.2.385-395.1996. J Bacteriol. 1996. PMID: 8550457 Free PMC article.
During cell growth in a chemically defined medium supplemented with 0.5 M NaCl, tetrahydropyrimidine derivatives (THPs), 2-methyl-4-carboxy-5-hydroxy-3,4,5,6-tetrahydropyrimidine [THP(A)] and, to a lesse …
During cell growth in a chemically defined medium supplemented with 0.5 M NaCl, tetrahydropyrimidine derivatives (THPs), 2-methyl
The structure and biosynthesis of new tetrahydropyrimidine derivatives in actinomycin D producer Streptomyces parvulus. Use of 13C- and 15N-labeled L-glutamate and 13C and 15N NMR spectroscopy.
Inbar L, Lapidot A. Inbar L, et al. J Biol Chem. 1988 Nov 5;263(31):16014-22. J Biol Chem. 1988. PMID: 2903148 Free article.
Two novel compounds, 2-methyl, 4-carboxy, 5-hydroxy-3,4,5,6-tetrahydropyrimidine (THP(A] and 2-methyl, 4-carboxy-3,4,5,6-tetrahydropyrimidine (THP(B] have been identified in the pool of Streptomyces parv …
Two novel compounds, 2-methyl, 4-carboxy, 5-hydroxy-3,4,5,6-tetrahy
The conformation of new tetrahydropyrimidine derivatives in solution and in the crystal.
Inbar L, Frolow F, Lapidot A. Inbar L, et al. Eur J Biochem. 1993 Jun 15;214(3):897-906. doi: 10.1111/j.1432-1033.1993.tb17993.x. Eur J Biochem. 1993. PMID: 8319696 Free article.
We have recently identified by NMR techniques two new tetrahydropyrimidine derivatives, 2-methyl-4-carboxy-5-hydroxy-3,4,5,6-tetrahydropyrimidine [THP(A)] and 2-methyl-4-carboxy-3,4,5,6-tetrahydropyrimid …
We have recently identified by NMR techniques two new tetrahydropyrimidine derivatives, 2-methyl-4-carboxy-5
Tetrahydropyrimidine derivatives inhibit binding of a Tat-like, arginine-containing peptide, to HIV TAR RNA in vitro.
Lapidot A, Ben-Asher E, Eisenstein M. Lapidot A, et al. FEBS Lett. 1995 Jun 19;367(1):33-8. doi: 10.1016/0014-5793(95)00514-a. FEBS Lett. 1995. PMID: 7541373 Free article.
The ability of a small molecule, 2-methyl,4-carboxy,5-hydroxy-3,4,5,6-tetrahydropyrimidine (THP(A)), which accumulates intracellularly in various streptomyces, to inhibit the interaction of Tat peptide ( …
The ability of a small molecule, 2-methyl,4-carboxy,5-hydroxy-3,4,5,6- …