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Year Number of Results
2001 1
2002 10
2003 4
2004 6
2005 17
2006 4
2007 7
2008 5
2009 4
2010 3
2011 4
2012 4
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2014 3
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Page 1
Noladin ether acts on trabecular meshwork cannabinoid (CB1) receptors to enhance aqueous humor outflow facility.
Njie YF, Kumar A, Qiao Z, Zhong L, Song ZH. Njie YF, et al. Invest Ophthalmol Vis Sci. 2006 May;47(5):1999-2005. doi: 10.1167/iovs.05-0729. Invest Ophthalmol Vis Sci. 2006. PMID: 16639008
The effect of 30 nM of noladin ether was completely blocked by SR141716A, a selective CB1 antagonist. ...These noladin ether-induced morphologic changes were also blocked by SR141716A and PD98059. ...
The effect of 30 nM of noladin ether was completely blocked by SR141716A, a selective CB1 antagonist. ...These noladin …
Noladin ether, a putative endocannabinoid, attenuates sensory neurotransmission in the rat isolated mesenteric arterial bed via a non-CB1/CB2 G(i/o) linked receptor.
Duncan M, Millns P, Smart D, Wright JE, Kendall DA, Ralevic V. Duncan M, et al. Br J Pharmacol. 2004 Jun;142(3):509-18. doi: 10.1038/sj.bjp.0705789. Epub 2004 May 17. Br J Pharmacol. 2004. PMID: 15148262 Free PMC article.
Noladin ether (0.1-3 microm) attenuated sensory neurogenic relaxation in a concentration-dependent manner. Noladin ether (1 microm) reduced vasorelaxation at a submaximal frequency (8 Hz), from 57.3+/-6.8 to 23.3+/-3.8% (P<0.05, n=4). 3 The inhibito …
Noladin ether (0.1-3 microm) attenuated sensory neurogenic relaxation in a concentration-dependent manner. Noladin e …
Ether-linked analogue of 2-arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species.
Oka S, Tsuchie A, Tokumura A, Muramatsu M, Suhara Y, Takayama H, Waku K, Sugiura T. Oka S, et al. J Neurochem. 2003 Jun;85(6):1374-81. doi: 10.1046/j.1471-4159.2003.01804.x. J Neurochem. 2003. PMID: 12787057 Free article.
2-Eicosa-5',8',11',14'-tetraenylglycerol (2-AG ether, HU310, noladin ether) is a metabolically stable ether-linked analogue of 2-arachidonoylglycerol (2-AG), an endogenous cannabinoid receptor ligand. 2-AG ether has been used as a valuable experimental tool by a num …
2-Eicosa-5',8',11',14'-tetraenylglycerol (2-AG ether, HU310, noladin ether) is a metabolically stable ether-linked analogue of …
Noladin ether, a putative endocannabinoid, enhances motivation to eat after acute systemic administration in rats.
Jones EK, Kirkham TC. Jones EK, et al. Br J Pharmacol. 2012 Jul;166(6):1815-21. doi: 10.1111/j.1476-5381.2012.01888.x. Br J Pharmacol. 2012. PMID: 22309979 Free PMC article.
This study examined the acute actions of the putative endocannabinoid noladin ether on food intake and eating motivation, assessing how it affects the amount of work expended by animals to obtain food. EXPERIMENTAL APPROACH Non-deprived male rats were injected syste …
This study examined the acute actions of the putative endocannabinoid noladin ether on food intake and eating motivation, asse …
Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues.
Fezza F, Bisogno T, Minassi A, Appendino G, Mechoulam R, Di Marzo V. Fezza F, et al. FEBS Lett. 2002 Feb 27;513(2-3):294-8. doi: 10.1016/s0014-5793(02)02341-4. FEBS Lett. 2002. PMID: 11904167 Free article.
The occurrence of the novel proposed endocannabinoid, noladin ether (2-arachidonyl glyceryl ether, 2-AGE) in various rat organs and brain regions, and its inactivation by intact C6 glioma cells, were studied. 2-AGE was measured by isotope dilution liquid chromatogra …
The occurrence of the novel proposed endocannabinoid, noladin ether (2-arachidonyl glyceryl ether, 2-AGE) in various rat organ …
Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide.
Milton NG. Milton NG. Neurosci Lett. 2002 Oct 31;332(2):127-30. doi: 10.1016/s0304-3940(02)00936-9. Neurosci Lett. 2002. PMID: 12384227
Anandamide and noladin ether, at nanomolar concentrations, showed concentration dependent inhibition of Abeta toxicity. A CB(1) cannabinoid receptor antagonist, AM251, prevented the protective effects of anandamide and noladin ether. The mitogen activa …
Anandamide and noladin ether, at nanomolar concentrations, showed concentration dependent inhibition of Abeta toxicity. A CB(1 …
Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors.
Páldyová E, Bereczki E, Sántha M, Wenger T, Borsodi A, Benyhe S. Páldyová E, et al. Neurochem Int. 2008 Jan;52(1-2):321-8. doi: 10.1016/j.neuint.2007.06.033. Epub 2007 Jul 4. Neurochem Int. 2008. PMID: 17698254
We examined the occurrence of possible changes in mRNA expression and the functional activity of opioid receptors after acute in vivo and in vitro treatment with the putative endogenous cannabinoid noladin ether. While noladin ether (NE) demonstrates a …
We examined the occurrence of possible changes in mRNA expression and the functional activity of opioid receptors after acute in vivo and in …
Synthesis, in vitro evaluation, and intraocular pressure effects of water-soluble prodrugs of endocannabinoid noladin ether.
Juntunen J, Vepsäläinen J, Niemi R, Laine K, Järvinen T. Juntunen J, et al. J Med Chem. 2003 Nov 6;46(23):5083-6. doi: 10.1021/jm030877j. J Med Chem. 2003. PMID: 14584958
The synthesized mono- and diphosphate esters of noladin ether (4 and 6) considerably increased the aqueous solubility of noladin ether (>40000-fold), showed high stability against chemical hydrolysis in buffer solutions, and were rapidly converted t …
The synthesized mono- and diphosphate esters of noladin ether (4 and 6) considerably increased the aqueous solubility of no …
The cannabinoid receptors.
Howlett AC. Howlett AC. Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:619-31. doi: 10.1016/s0090-6980(02)00060-6. Prostaglandins Other Lipid Mediat. 2002. PMID: 12432948 Review.
Those compounds identified to date include the eicosanoids arachidonoylethanolamide (anandamide), 2-arachidonoylglycerol and 2-arachidonylglyceryl ether (noladin ether). Several excellent reviews on endocannabinoids and their synthesis, metabolism and function have …
Those compounds identified to date include the eicosanoids arachidonoylethanolamide (anandamide), 2-arachidonoylglycerol and 2-arachidonylgl …
75 results