Apoptosis

A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.

Year introduced: 1993

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G04.146.954.035

MeSH Unique ID: D017209

Entry Terms:

• Classic Apoptosis
• Apoptosis, Classic
• Classic Apoptoses
• Programmed Cell Death, Type I
• Classical Apoptosis
• Apoptosis, Classical
• Apoptosis, Intrinsic Pathway
• Apoptoses, Intrinsic Pathway
• Intrinsic Pathway Apoptoses
• Intrinsic Pathway Apoptosis
• Apoptosis, Extrinsic Pathway
• Apoptoses, Extrinsic Pathway
• Extrinsic Pathway Apoptoses
• Extrinsic Pathway Apoptosis
• Caspase-Dependent Apoptosis
• Apoptosis, Caspase-Dependent
• Caspase Dependent Apoptosis
• Programmed Cell Death
• Cell Death, Programmed

Previous Indexing:

• Cell Survival (1972-1992)

See Also:

• Necrosis
• Caspases
• In Situ Nick-End Labeling
• Cellular Apoptosis Susceptibility Protein
• Genes, Transgenic, Suicide
• Death Domain Receptor Signaling Adaptor Proteins
• CARD Signaling Adaptor Proteins

All MeSH Categories
Phenomena and Processes Category
Cell Physiological Phenomena
Cell Death
Regulated Cell Death
Apoptosis
Anoikis
Eryptosis
Pyroptosis