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1988 2
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1997 3
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Page 1
A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection.
Klimberg IW, Cox CE 2nd, Fowler CL, King W, Kim SS, Callery-D'Amico S. Klimberg IW, et al. Urology. 1998 Apr;51(4):610-5. doi: 10.1016/s0090-4295(97)00708-5. Urology. 1998. PMID: 9586615 Clinical Trial.
METHODS: Outpatients were randomized to receive levofloxacin (250 mg once daily) for 7 to 10 days or lomefloxacin (400 mg once daily) for 14 days. Three hundred thirty-six patients (171 with levofloxacin, 165 with lomefloxacin) were evaluable for microbiologic effic …
METHODS: Outpatients were randomized to receive levofloxacin (250 mg once daily) for 7 to 10 days or lomefloxacin (400 mg once daily) …
Interaction study of lomefloxacin and ciprofloxacin with omeprazole and comparative pharmacokinetics.
Stuht H, Lode H, Koeppe P, Rost KL, Schaberg T. Stuht H, et al. Antimicrob Agents Chemother. 1995 May;39(5):1045-9. doi: 10.1128/AAC.39.5.1045. Antimicrob Agents Chemother. 1995. PMID: 7625786 Free PMC article. Clinical Trial.
Another objective was to compare the pharmacokinetics of lomefloxacin and ciprofloxacin. Twelve healthy volunteers participated. ...Concomitant therapy with omeprazole did not alter the pharmacokinetics of lomefloxacin or ciprofloxacin in these single-dose studies.. …
Another objective was to compare the pharmacokinetics of lomefloxacin and ciprofloxacin. Twelve healthy volunteers participated. ...C …
Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis.
Erjongmanee S, Kasetsuwan N, Phusitphoykai N, Puangsricharern V, Pariyakanok L. Erjongmanee S, et al. J Med Assoc Thai. 2004 Sep;87 Suppl 2:S83-90. J Med Assoc Thai. 2004. PMID: 16083168 Clinical Trial.
OBJECTIVE: To evaluate the efficacy and safety of 0.3% lomefloxacin single agent solution, by comparing to a combination of fortified ophthalmic solutions of cefazolin sodium 50 mg/ml and gentamicin sulfate 14 mg/ml, in the treatment of acute bacterial keratitis. ...CONCLU …
OBJECTIVE: To evaluate the efficacy and safety of 0.3% lomefloxacin single agent solution, by comparing to a combination of fortified …
Comparison of the safety and efficacy of lomefloxacin and trimethoprim/sulfamethoxazole in the treatment of uncomplicated urinary tract infections: results from a multicenter study.
Andrade-Villanueva J, Flores-Gaxiola A, Lopez-Guillen P, Aguirre-Avalos G, Morfin-Otero R, Rodriguez-Noriega E. Andrade-Villanueva J, et al. Am J Med. 1992 Apr 6;92(4A):71S-74S. doi: 10.1016/0002-9343(92)90313-z. Am J Med. 1992. PMID: 1316074 Clinical Trial.
Clinical success 5-9 days post-therapy was noted in 99.2% of patients in the lomefloxacin group and in 98.3% of patients in the TMP/SMX group (p = 0.5138). Adverse events probably related to treatment occurred in 6% of those treated with lomefloxacin and in 7% of pa …
Clinical success 5-9 days post-therapy was noted in 99.2% of patients in the lomefloxacin group and in 98.3% of patients in the TMP/S …
Use of quinolones in treatment of prostatitis and lower urinary tract infections.
Andriole VT. Andriole VT. Eur J Clin Microbiol Infect Dis. 1991 Apr;10(4):342-50. doi: 10.1007/BF01967009. Eur J Clin Microbiol Infect Dis. 1991. PMID: 1864295 Review.
The newer quinolones, ciprofloxacin, enoxacin, fleroxacin, lomefloxacin, norfloxacin, ofloxacin and pefloxacin are highly effective antimicrobial agents against the majority of bacteria responsible for urinary tract infections and bacterial prostatitis. The pharmacokinetic …
The newer quinolones, ciprofloxacin, enoxacin, fleroxacin, lomefloxacin, norfloxacin, ofloxacin and pefloxacin are highly effective a …
A comparison of the safety and efficacy of lomefloxacin and ciprofloxacin in the treatment of complicated or recurrent urinary tract infections.
Cox CE. Cox CE. Am J Med. 1992 Apr 6;92(4A):82S-86S. doi: 10.1016/0002-9343(92)90315-3. Am J Med. 1992. PMID: 1316077 Clinical Trial.
A total of 142 patients met the criteria for efficacy evaluation, 72 in the lomefloxacin group and 70 in the ciprofloxacin group. Eradication of the initial pathogen (post-treatment culture of less than or equal to 10(4) colony-forming units (CFU)/mL) was noted in 97.2% of …
A total of 142 patients met the criteria for efficacy evaluation, 72 in the lomefloxacin group and 70 in the ciprofloxacin group. Era …
Levofloxacin versus ciprofloxacin versus lomefloxacin in acute pyelonephritis.
Richard GA, Klimberg IN, Fowler CL, Callery-D'Amico S, Kim SS. Richard GA, et al. Urology. 1998 Jul;52(1):51-5. doi: 10.1016/s0090-4295(98)00160-5. Urology. 1998. PMID: 9671870 Clinical Trial.
OBJECTIVES: To evaluate, in two randomized, multicenter trials, levofloxacin compared with ciprofloxacin and lomefloxacin for efficacy and safety in treating acute pyelonephritis. ...At 5 to 9 days after the end of treatment, 95% of uropathogens were eradicated in patients …
OBJECTIVES: To evaluate, in two randomized, multicenter trials, levofloxacin compared with ciprofloxacin and lomefloxacin for efficac …
Lack of phototoxicity potential with delafloxacin in healthy male and female subjects: comparison to lomefloxacin.
Dawe RS, Ferguson J, Ibbotson S, Lawrence L, Paulson S, Duffy E, Cammarata S. Dawe RS, et al. Photochem Photobiol Sci. 2018 Jun 13;17(6):773-780. doi: 10.1039/c8pp00019k. Photochem Photobiol Sci. 2018. PMID: 29721574 Clinical Trial.
The phototoxic index results were significantly higher for lomefloxacin at 335 nm and 365 nm compared to placebo and delafloxacin. ...Delafloxacin and placebo failed to demonstrate a phototoxic effect but lomefloxacin, the positive control, demonstrated moderate pho …
The phototoxic index results were significantly higher for lomefloxacin at 335 nm and 365 nm compared to placebo and delafloxacin. .. …
Topical lomefloxacin 0.3% twice daily versus tobramycin 0.3% in acute bacterial conjunctivitis: A multicenter double-blind phase III study.
Gallenga PE, Lobefalo L, Colangelo L, Della Loggia G, Orzalesi N, Velati P, Bujtar E, Ponte F, Damiani S, Bucci MG, Bonini S, Curatola MR, Palma LA, Bonomi L, Tomazzoli Gerosa L, Pagliarusco A, Milan E, Jauch A. Gallenga PE, et al. Ophthalmologica. 1999;213(4):250-7. doi: 10.1159/000027430. Ophthalmologica. 1999. PMID: 10420109 Clinical Trial.
METHODS: Ninety-nine subjects were enrolled: 50 were treated with lomefloxacin 0.3% eye drops twice daily and 49 with tobramycin 0.3% eye drops 4 times daily. ...Lomefloxacin caused less resistance than other antibiotics evaluated....
METHODS: Ninety-nine subjects were enrolled: 50 were treated with lomefloxacin 0.3% eye drops twice daily and 49 with tobramycin 0.3% …
Comparative bronchoalveolar concentrations of ciprofloxacin and lomefloxacin following oral administration.
Baldwin DR, Wise R, Andrews JM, Gill M, Honeybourne D. Baldwin DR, et al. Respir Med. 1993 Nov;87(8):595-601. doi: 10.1016/s0954-6111(05)80262-8. Respir Med. 1993. PMID: 8290743 Clinical Trial.
In a comparative study, the concentrations of two fluoroquinolone antimicrobials, ciprofloxacin and lomefloxacin, were measured in serum, bronchial mucosal biopsies, epithelial lining fluid (ELF) and alveolar macrophages (AM). Thirty-four subjects received either ciproflox …
In a comparative study, the concentrations of two fluoroquinolone antimicrobials, ciprofloxacin and lomefloxacin, were measured in se …
91 results