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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 2
1959 1
1962 1
1963 1
1964 1
1965 5
1966 2
1968 5
1969 9
1970 15
1971 12
1972 18
1973 12
1974 23
1975 23
1976 20
1977 24
1978 32
1979 23
1980 27
1981 33
1982 36
1983 33
1984 42
1985 44
1986 50
1987 68
1988 56
1989 69
1990 74
1991 74
1992 81
1993 92
1994 63
1995 95
1996 95
1997 102
1998 95
1999 93
2000 70
2001 87
2002 76
2003 91
2004 99
2005 88
2006 98
2007 113
2008 105
2009 96
2010 151
2011 128
2012 143
2013 150
2014 175
2015 154
2016 195
2017 202
2018 164
2019 198
2020 199
2021 200
2022 189
2023 183
2024 53

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4,604 results

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Page 1
Long-term management of hepatic encephalopathy with lactulose and/or rifaximin: a review of the evidence.
Hudson M, Schuchmann M. Hudson M, et al. Eur J Gastroenterol Hepatol. 2019 Apr;31(4):434-450. doi: 10.1097/MEG.0000000000001311. Eur J Gastroenterol Hepatol. 2019. PMID: 30444745 Free PMC article. Review.
Long-term safety/tolerability outcomes were reported in six articles for treatment with lactulose alone and nine articles for treatment with rifaximin, alone or in combination with lactulose. These studies showed that lactulose is effective for the prevention …
Long-term safety/tolerability outcomes were reported in six articles for treatment with lactulose alone and nine articles for treatme …
Combination therapy with rifaximin and lactulose in hepatic encephalopathy: A systematic review and meta-analysis.
Fu J, Gao Y, Shi L. Fu J, et al. PLoS One. 2022 Apr 26;17(4):e0267647. doi: 10.1371/journal.pone.0267647. eCollection 2022. PLoS One. 2022. PMID: 35471992 Free PMC article.
Rifaximin and lactulose are widely used in patients with hepatic encephalopathy (HE); however, data on whether the combined use of rifaximin and lactulose could yield additional benefits for patients with HE are limited and inconclusive. ...Moreover, the use of rifa …
Rifaximin and lactulose are widely used in patients with hepatic encephalopathy (HE); however, data on whether the combined use of ri …
Heretical thoughts into hepatic encephalopathy.
Jalan R, Rose CF. Jalan R, et al. J Hepatol. 2022 Aug;77(2):539-548. doi: 10.1016/j.jhep.2022.03.014. Epub 2022 Mar 28. J Hepatol. 2022. PMID: 35358618 Review.
Many lines of investigation have confirmed that hepatic encephalopathy is irreversible in many patients and suggest the need for further studies focussing on mechanisms of neuronal injury and death, to guide future drug development for these patients. The clinical evidence behind …
Many lines of investigation have confirmed that hepatic encephalopathy is irreversible in many patients and suggest the need for further stu …
Bei Leberzirrhose immer Lactulose geben?
M Schleicher E, Labenz C. M Schleicher E, et al. MMW Fortschr Med. 2024 Feb;166(3):26. doi: 10.1007/s15006-024-3651-7. MMW Fortschr Med. 2024. PMID: 38389000 Review. German. No abstract available.
Lactulose--a multifaceted substance.
Huchzermeyer H, Schumann C. Huchzermeyer H, et al. Z Gastroenterol. 1997 Oct;35(10):945-55. Z Gastroenterol. 1997. PMID: 9370144 Review.
Lactulose is therapeutically used in hepatic encephalopathy, constipation, and salmonellosis. ...Lactulose presumably reduces pathogenic bacteria in favor of the health promoting bifidusflora; also, production and absorption of endotoxines may be reduced; this sugge
Lactulose is therapeutically used in hepatic encephalopathy, constipation, and salmonellosis. ...Lactulose presumably reduces
Lactulose.
[No authors listed] [No authors listed] Nurs Times. 2006 Jan 31-Feb 6;102(5):31. Nurs Times. 2006. PMID: 16475577 No abstract available.
A randomized, double-blind, controlled trial comparing rifaximin plus lactulose with lactulose alone in treatment of overt hepatic encephalopathy.
Sharma BC, Sharma P, Lunia MK, Srivastava S, Goyal R, Sarin SK. Sharma BC, et al. Am J Gastroenterol. 2013 Sep;108(9):1458-63. doi: 10.1038/ajg.2013.219. Epub 2013 Jul 23. Am J Gastroenterol. 2013. PMID: 23877348 Clinical Trial.
There was a significant decrease in mortality after treatment with lactulose plus rifaximin vs. lactulose and placebo (23.8% vs. 49.1%, P<0.05). ...CONCLUSION: Combination of lactulose plus rifaximin is more effective than lactulose alone in the tre …
There was a significant decrease in mortality after treatment with lactulose plus rifaximin vs. lactulose and placebo (23.8% v …
Lactitol.
[No authors listed] [No authors listed] Lancet. 1987 Jul 11;2(8550):81-2. Lancet. 1987. PMID: 2885579 No abstract available.
The potential role of lactulose pharmacotherapy in the treatment and prevention of diabetes.
Chu N, Ling J, Jie H, Leung K, Poon E. Chu N, et al. Front Endocrinol (Lausanne). 2022 Sep 15;13:956203. doi: 10.3389/fendo.2022.956203. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36187096 Free PMC article. Review.
The mechanism of action of lactulose remains unclear, but it elicits more than osmotic laxative effects. As a prebiotic, lactulose may act as a bifidogenic factor with positive effects in preventing and controlling diabetes. ...
The mechanism of action of lactulose remains unclear, but it elicits more than osmotic laxative effects. As a prebiotic, lactulose
Recent advances on prebiotic lactulose production.
Sitanggang AB, Drews A, Kraume M. Sitanggang AB, et al. World J Microbiol Biotechnol. 2016 Sep;32(9):154. doi: 10.1007/s11274-016-2103-7. Epub 2016 Jul 27. World J Microbiol Biotechnol. 2016. PMID: 27465854 Review.
Lactulose, a synthetic disaccharide, has received increasing interest due to its role as a prebiotic. ...The industrial production of lactulose is still mainly done by chemical isomerization. Due to concerns on the environmental and tedious separation processes, the
Lactulose, a synthetic disaccharide, has received increasing interest due to its role as a prebiotic. ...The industrial production of
4,604 results