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Effect of Caffeine on the Bioavailability and Pharmacokinetics of an Acetylsalicylic Acid-Paracetamol Combination: Results of a Phase I Study.
Weiser T, Weigmann H. Weiser T, et al. Adv Ther. 2019 Mar;36(3):597-607. doi: 10.1007/s12325-019-0891-5. Epub 2019 Feb 13. Adv Ther. 2019. PMID: 30758744 Free PMC article. Clinical Trial.
The present study aimed to determine the effect of caffeine on the pharmacokinetics of acetylsalicylic acid (ASA) and paracetamol when used as a fixed-dose ASA/paracetamol/caffeine combination. ...The primary end points were the area under the concentration-t …
The present study aimed to determine the effect of caffeine on the pharmacokinetics of acetylsalicylic acid (ASA) and paraceta …
Comparative bioequivalence study of different brands of acetyl salicylic acid in human volunteers.
Valecha N, Gupta U, Mehta VL. Valecha N, et al. Eur J Drug Metab Pharmacokinet. 1993 Jul-Sep;18(3):251-3. doi: 10.1007/BF03188804. Eur J Drug Metab Pharmacokinet. 1993. PMID: 8149942 Clinical Trial.
Single dose (700 mg) of buffered aspirin or aspirin with calcium carbonate or aspirin with caffeine was administered orally, at least 3 days apart. Blood samples were drawn at different time intervals after administration of drug for estimation of salicylate levels. ...
Single dose (700 mg) of buffered aspirin or aspirin with calcium carbonate or aspirin with caffeine was administered orally, at least …