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Effect of omega-3 ethyl esters on the triglyceride-rich lipoprotein response to endotoxin challenge in healthy young men.
Walker RE, Richter CK, Skulas-Ray AC, Flock MR, Harsch BA, Annevelink CE, Kris-Etherton PM, Jensen GL, Shearer GC. Walker RE, et al. J Lipid Res. 2023 May;64(5):100353. doi: 10.1016/j.jlr.2023.100353. Epub 2023 Mar 11. J Lipid Res. 2023. PMID: 36907552 Free PMC article. Clinical Trial.
Inflammation elevates TGRL concentrations, but it is unknown if the fatty acid and oxylipin compositions change. In this study, we investigated the effect of prescription omega-3 acid ethyl esters (P-OM3; 3.4 g/d EPA + DHA) on the lipid response …
Inflammation elevates TGRL concentrations, but it is unknown if the fatty acid and oxylipin compositions change. In this study, we in …
N-3 Polyunsaturated fatty acid ethyl esters decrease the invasion, but not the proliferation, of human colorectal cancer cells via a PI3K-dependent mechanism in vitro.
Pfister E, Smith R, Lane MA. Pfister E, et al. Prostaglandins Leukot Essent Fatty Acids. 2021 Apr;167:102273. doi: 10.1016/j.plefa.2021.102273. Epub 2021 Mar 24. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 33812216
N-3 polyunsaturated fatty acid (PUFA) ethyl esters have been approved by the FDA for the treatment of dyslipidemia and are promising cancer therapeutics. The study objectives were to determine if and how n-3 PUFA ethyl esters affected the proliferation and in …
N-3 polyunsaturated fatty acid (PUFA) ethyl esters have been approved by the FDA for the treatment of dyslipidemia and are pro …
Reduction of circulating FABP4 level by treatment with omega-3 fatty acid ethyl esters.
Furuhashi M, Hiramitsu S, Mita T, Omori A, Fuseya T, Ishimura S, Watanabe Y, Hoshina K, Matsumoto M, Tanaka M, Moniwa N, Yoshida H, Ishii J, Miura T. Furuhashi M, et al. Lipids Health Dis. 2016 Jan 12;15:5. doi: 10.1186/s12944-016-0177-8. Lipids Health Dis. 2016. PMID: 26754658 Free PMC article. Clinical Trial.
Change in FABP4 level by omega-3 fatty acids was negatively correlated with change in levels of EPA + DHA (r = -0.643, P = 0.013), EPA (r = -0.540, P = 0.046) and DHA (r = -0.650, P = 0.011) but not change in the level of triglycerides or other fatt …
Change in FABP4 level by omega-3 fatty acids was negatively correlated with change in levels of EPA + DHA (r = - …
Red blood cell oleic acid levels reflect olive oil intake while omega-3 levels reflect fish intake and the use of omega-3 acid ethyl esters: The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico-Heart Failure trial.
Harris WS, Masson S, Barlera S, Milani V, Pileggi S, Franzosi MG, Marchioli R, Tognoni G, Tavazzi L, Latini R; GISSI-HF Investigators. Harris WS, et al. Nutr Res. 2016 Sep;36(9):989-994. doi: 10.1016/j.nutres.2016.06.012. Epub 2016 Jun 28. Nutr Res. 2016. PMID: 27632919 Clinical Trial.
We hypothesized that treatment with prescription omega-3 acid ethyl esters (O3AEE) would increase the omega-3 index to the proposed cardioprotective value of 8%. ...At 3 months, more patients reached the proposed target omega-3 …
We hypothesized that treatment with prescription omega-3 acid ethyl esters (O3AEE) would increase the omega …
Enhanced increase of omega-3 index in response to long-term n-3 fatty acid supplementation from triacylglycerides versus ethyl esters.
Neubronner J, Schuchardt JP, Kressel G, Merkel M, von Schacky C, Hahn A. Neubronner J, et al. Eur J Clin Nutr. 2011 Feb;65(2):247-54. doi: 10.1038/ejcn.2010.239. Epub 2010 Nov 10. Eur J Clin Nutr. 2011. PMID: 21063431 Clinical Trial.
The objective of this study was to investigate the response of the omega-3 index, the percentage of EPA+DHA in red blood cell membranes, to supplementation with two different omega-3 fatty acid (n-3 FA) formulations in humans. ...CONCLUSION: A s …
The objective of this study was to investigate the response of the omega-3 index, the percentage of EPA+DHA in red blood cell …
The bioavailability and pharmacodynamics of different concentrations of omega-3 acid ethyl esters.
Bryhn M, Hansteen H, Schanche T, Aakre SE. Bryhn M, et al. Prostaglandins Leukot Essent Fatty Acids. 2006 Jul;75(1):19-24. doi: 10.1016/j.plefa.2006.04.003. Epub 2006 Jun 27. Prostaglandins Leukot Essent Fatty Acids. 2006. PMID: 16806871 Clinical Trial.
Omega-3 fatty acids have a long history of use as dietary supplements and more recently for therapeutic applications as prescription pharmaceuticals. ...The objective of the study was to explore the uptake and effects of different concentrations of …
Omega-3 fatty acids have a long history of use as dietary supplements and more recently for therapeutic applicat …
Dietary Eicosapentaenoic Acid and Docosahexaenoic Acid Ethyl Esters Influence the Gut Microbiota and Bacterial Metabolites in Rats.
Hosomi R, Matsudo A, Sugimoto K, Shimono T, Kanda S, Nishiyama T, Yoshida M, Fukunaga K. Hosomi R, et al. J Oleo Sci. 2021 Oct 5;70(10):1469-1480. doi: 10.5650/jos.ess21189. Epub 2021 Sep 8. J Oleo Sci. 2021. PMID: 34497184 Free article.
However, few reports have focused on the effects of EPA and DHA on gut microbiota diversity and bacterial metabolites. This study evaluated the effects of dietary EPA-ethyl ester (EE) and DHA-EE on steroid metabolism, gut microbiota, and bacterial metabolites in Wistar rat …
However, few reports have focused on the effects of EPA and DHA on gut microbiota diversity and bacterial metabolites. This study evaluated …
The enteral bioavailability of eicosapentaenoic acid and docosahexaenoic acid is as good from ethyl esters as from glyceryl esters in spite of lower hydrolytic rates by pancreatic lipase in vitro.
Krokan HE, Bjerve KS, Mørk E. Krokan HE, et al. Biochim Biophys Acta. 1993 May 20;1168(1):59-67. doi: 10.1016/0005-2760(93)90266-c. Biochim Biophys Acta. 1993. PMID: 8504143
Under similar conditions release of AA from glyceryl ester and ethyl ester was essentially similar and approx. 1.5-fold faster than release of EPA and DHA from ethyl esters. ...Thus, the order of the rates of hydrolyses was olive oil > TG30 > TG85 > triarac …
Under similar conditions release of AA from glyceryl ester and ethyl ester was essentially similar and approx. 1.5-fold faster than r …
Study of the pharmacokinetic interaction between simvastatin and prescription omega-3-acid ethyl esters.
McKenney JM, Swearingen D, Di Spirito M, Doyle R, Pantaleon C, Kling D, Shalwitz RA. McKenney JM, et al. J Clin Pharmacol. 2006 Jul;46(7):785-91. doi: 10.1177/0091270006289849. J Clin Pharmacol. 2006. PMID: 16809804 Clinical Trial.
The coadministration of prescription omega-3-acid ethyl esters (P-OM3) with a statin may present a treatment option for patients with mixed hyperlipidemia. ...
The coadministration of prescription omega-3-acid ethyl esters (P-OM3) with a statin may present a treatment opt …
Limited impact of 2 g/day omega-3 fatty acid ethyl esters (Omacor) on plasma lipids and inflammatory markers in patients awaiting carotid endarterectomy.
Yusof HM, Cawood AL, Ding R, Williams JA, Napper FL, Shearman CP, Grimble RF, Payne SP, Calder PC. Yusof HM, et al. Mar Drugs. 2013 Sep 20;11(9):3569-81. doi: 10.3390/md11093569. Mar Drugs. 2013. PMID: 24065166 Free PMC article.
The objective of this study was to determine the effects of prescription omega-3 (n-3) fatty acid ethyl esters (Omacor) on blood pressure, plasma lipids, and inflammatory marker concentrations in patients awaiting carotid endarterectomy. ...This may be …
The objective of this study was to determine the effects of prescription omega-3 (n-3) fatty acid ethyl esters ( …
23 results