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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1989 2
1991 4
1992 1
1993 7
1994 4
1995 6
1996 6
1997 4
1998 1
1999 4
2000 2
2002 1
2005 1
2012 1
2015 1
2016 1
2024 0

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46 results

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Page 1
Felbamate for partial seizures: results of a controlled clinical trial.
Leppik IE, Dreifuss FE, Pledger GW, Graves NM, Santilli N, Drury I, Tsay JY, Jacobs MP, Bertram E, Cereghino JJ, et al. Leppik IE, et al. Neurology. 1991 Nov;41(11):1785-9. doi: 10.1212/wnl.41.11.1785. Neurology. 1991. PMID: 1944909 Clinical Trial.
Felbamate (2-phenyl-1,3-propanediol dicarbamate) has a favorable preclinical profile in animal models of epilepsy. ...The mean felbamate dosage was 2,300 mg/d. Plasma felbamate concentrations ranged from 18.4 to 51.9 mg/l, mean = 32.5 mg/l. ...
Felbamate (2-phenyl-1,3-propanediol dicarbamate) has a favorable preclinical profile in animal models of epilepsy. ...The mean fel
Anticonvulsant drug hypersensitivity.
Galindo PA, Borja J, Gómez E, Mur P, Gudín M, García R, Encinas C, Romero G, Garrido JA, Cortina P, Feo F. Galindo PA, et al. J Investig Allergol Clin Immunol. 2002;12(4):299-304. J Investig Allergol Clin Immunol. 2002. PMID: 12926190 Clinical Trial.
The responsible drugs were carbamazepine (8 adverse reactions), phenytoin (5), lamotrigine (4), phenobarbital (4), sodium valproate (1), and felbamate (1). The drugs tolerated were sodium valproate (6 patients), topiramate (4), vigabatrin (2), lamotrigine (1), clonazepam ( …
The responsible drugs were carbamazepine (8 adverse reactions), phenytoin (5), lamotrigine (4), phenobarbital (4), sodium valproate (1), and …
Felbamate: a clinical trial for complex partial seizures.
Theodore WH, Raubertas RF, Porter RJ, Nice F, Devinsky O, Reeves P, Bromfield E, Ito B, Balish M. Theodore WH, et al. Epilepsia. 1991 May-Jun;32(3):392-7. doi: 10.1111/j.1528-1157.1991.tb04668.x. Epilepsia. 1991. PMID: 2044501 Clinical Trial.
We performed a randomized, double-blind, three-period cross-over study of felbamate (FBM, 2-phenyl-1,3-propanediol dicarbamate: Carter-Wallace 554) in patients with complex partial seizures. ...
We performed a randomized, double-blind, three-period cross-over study of felbamate (FBM, 2-phenyl-1,3-propanediol dicarbamate: Carte …
New anticonvulsant drugs. Focus on flunarizine, fosphenytoin, midazolam and stiripentol.
Bebin M, Bleck TP. Bebin M, et al. Drugs. 1994 Aug;48(2):153-71. doi: 10.2165/00003495-199448020-00003. Drugs. 1994. PMID: 7527321 Review.
These include vigabatrin, oxcarbazepine and lamotrigine in Europe, and felbamate and gabapentin in the US. In addition to these, 3 additional drugs are in the clinical investigational stage: flunarizine, fosphenytoin and stiripentol. ...
These include vigabatrin, oxcarbazepine and lamotrigine in Europe, and felbamate and gabapentin in the US. In addition to these, 3 ad …
Coadministration of phenytoin and felbamate: evidence of additional phenytoin dose-reduction requirements based on pharmacokinetics and tolerability with increasing doses of felbamate.
Sachdeo R, Wagner ML, Sachdeo S, Shumaker RC, Lyness WH, Rosenberg A, Ward D, Perhach JL. Sachdeo R, et al. Epilepsia. 1999 Aug;40(8):1122-8. doi: 10.1111/j.1528-1157.1999.tb00829.x. Epilepsia. 1999. PMID: 10448826 Free article. Clinical Trial.
PURPOSE: This open-label study investigated the pharmacokinetic interaction of phenytoin (PHT) and felbamate (FBM). METHODS: Ten subjects with epilepsy receiving PHT monotherapy were administered increasing doses of FBM (1,200, 1,800, 2,400-3,600 mg/day) at 2-week interval …
PURPOSE: This open-label study investigated the pharmacokinetic interaction of phenytoin (PHT) and felbamate (FBM). METHODS: Ten subj …
Effect of felbamate on phenytoin and carbamazepine serum concentrations.
Graves NM, Holmes GB, Fuerst RH, Leppik IE. Graves NM, et al. Epilepsia. 1989 Mar-Apr;30(2):225-9. doi: 10.1111/j.1528-1157.1989.tb05458.x. Epilepsia. 1989. PMID: 2647472 Clinical Trial.
Felbamate (FBM) is a novel antiepileptic drug (AED) undergoing clinical trials in the United States. ...
Felbamate (FBM) is a novel antiepileptic drug (AED) undergoing clinical trials in the United States. ...
Effects of felbamate on the pharmacokinetics of phenobarbital.
Reidenberg P, Glue P, Banfield CR, Colucci RD, Meehan JW, Radwanski E, Mojavarian P, Lin CC, Nezamis J, Guillaume M, et al. Reidenberg P, et al. Clin Pharmacol Ther. 1995 Sep;58(3):279-87. doi: 10.1016/0009-9236(95)90244-9. Clin Pharmacol Ther. 1995. PMID: 7554701 Clinical Trial.
The effects of felbamate on the pharmacokinetics of phenobarbital and one of its main metabolites, parahydroxyphenobarbital, were assessed in a parallel-group, placebo-controlled, double-blind study, in 24 healthy volunteers. Pharmacokinetic parameters of phenobarbital and …
The effects of felbamate on the pharmacokinetics of phenobarbital and one of its main metabolites, parahydroxyphenobarbital, were ass …
Felbamate in the treatment of Lennox-Gastaut syndrome: results of a 12-month open-label study following a randomized clinical trial.
Dodson WE. Dodson WE. Epilepsia. 1993;34 Suppl 7:S18-24. doi: 10.1111/j.1528-1157.1993.tb04590.x. Epilepsia. 1993. PMID: 8243374 Clinical Trial.
Felbamate (FBM) is a new antiepileptic drug (AED) that has been evaluated in partial seizures and in the Lennox-Gastaut syndrome (LGS). ...
Felbamate (FBM) is a new antiepileptic drug (AED) that has been evaluated in partial seizures and in the Lennox-Gastaut syndrome (LGS
Pharmacokinetic interaction studies between felbamate and vigabatrin.
Reidenberg P, Glue P, Banfield C, Colucci R, Meehan J, Rey E, Radwanski E, Nomeir A, Lim J, Lin C, et al. Reidenberg P, et al. Br J Clin Pharmacol. 1995 Aug;40(2):157-60. doi: 10.1111/j.1365-2125.1995.tb05770.x. Br J Clin Pharmacol. 1995. PMID: 8562299 Free PMC article. Clinical Trial.
In Study I, 18 subjects received oral vigabatrin 1000 mg every 12 h for two 8 days periods with felbamate 1200 mg every 12 h or placebo. In Study II, 18 other volunteers were administered oral felbamate 1200 mg every 12 h for two 8 days periods with vigabatrin 1000 …
In Study I, 18 subjects received oral vigabatrin 1000 mg every 12 h for two 8 days periods with felbamate 1200 mg every 12 h or place …
Effect of felbamate on the pharmacokinetics of lamotrigine.
Colucci R, Glue P, Holt B, Banfield C, Reidenberg P, Meehan JW, Pai S, Nomeir A, Lim J, Lin CC, Affrime MB. Colucci R, et al. J Clin Pharmacol. 1996 Jul;36(7):634-8. doi: 10.1002/j.1552-4604.1996.tb04228.x. J Clin Pharmacol. 1996. PMID: 8844446 Clinical Trial.
Volunteers were given lamotrigine (100 mg every 12 hours) and felbamate (1,200 mg every 12 hours) or matching placebo for 10 days during each period of the crossover. ...All other adverse events were primarily related to the central nervous system and gastrointestinal trac …
Volunteers were given lamotrigine (100 mg every 12 hours) and felbamate (1,200 mg every 12 hours) or matching placebo for 10 days dur …
46 results