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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 3
1982 8
1983 7
1984 6
1985 15
1986 12
1987 14
1988 18
1989 25
1990 24
1991 21
1992 36
1993 30
1994 24
1995 39
1996 27
1997 33
1998 34
1999 33
2000 27
2001 29
2002 24
2003 28
2004 29
2005 30
2006 26
2007 31
2008 17
2009 17
2010 9
2011 23
2012 24
2013 20
2014 18
2015 18
2016 13
2017 20
2018 8
2019 12
2020 8
2021 7
2022 11
2023 9
2024 5

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841 results

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Page 1
Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial.
Keij FM, Kornelisse RF, Hartwig NG, van der Sluijs-Bens J, van Beek RHT, van Driel A, van Rooij LGM, van Dalen-Vink I, Driessen GJA, Kenter S, von Lindern JS, Eijkemans M, Stam-Stigter GM, Qi H, van den Berg MM, Baartmans MGA, van der Meer-Kappelle LH, Meijssen CB, Norbruis OF, Heidema J, van Rossem MC, den Butter PCP, Allegaert K, Reiss IKM, Tramper-Stranders GA. Keij FM, et al. Lancet Child Adolesc Health. 2022 Nov;6(11):799-809. doi: 10.1016/S2352-4642(22)00245-0. Epub 2022 Sep 9. Lancet Child Adolesc Health. 2022. PMID: 36088952 Clinical Trial.
A margin of 3% was deemed to indicate non-inferiority, thus if the reinfection rate in the oral amoxicillin-clavulanic acid group was less than 3% higher than that in the intravenous antibiotic group the null hypothesis would be rejected. ...In the intention- …
A margin of 3% was deemed to indicate non-inferiority, thus if the reinfection rate in the oral amoxicillin-clavulanic acid …
Identifying Children Likely to Benefit From Antibiotics for Acute Sinusitis: A Randomized Clinical Trial.
Shaikh N, Hoberman A, Shope TR, Jeong JH, Kurs-Lasky M, Martin JM, Bhatnagar S, Muniz GB, Block SL, Andrasko M, Lee MC, Rajakumar K, Wald ER. Shaikh N, et al. JAMA. 2023 Jul 25;330(4):349-358. doi: 10.1001/jama.2023.10854. JAMA. 2023. PMID: 37490085 Free PMC article. Clinical Trial.
The trial was conducted between February 2016 and April 2022 at primary care offices affiliated with 6 US institutions and was designed to evaluate whether symptom burden differed in subgroups defined by nasopharyngeal Streptococcus pneumoniae, Haemophilus influenzae, or Moraxell …
The trial was conducted between February 2016 and April 2022 at primary care offices affiliated with 6 US institutions and was designed to e …
Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial.
Vons C, Barry C, Maitre S, Pautrat K, Leconte M, Costaglioli B, Karoui M, Alves A, Dousset B, Valleur P, Falissard B, Franco D. Vons C, et al. Lancet. 2011 May 7;377(9777):1573-9. doi: 10.1016/S0140-6736(11)60410-8. Lancet. 2011. PMID: 21550483 Clinical Trial.
BACKGROUND: Researchers have suggested that antibiotics could cure acute appendicitis. We assessed the efficacy of amoxicillin plus clavulanic acid by comparison with emergency appendicectomy for treatment of patients with uncomplicated acute appendicitis. .. …
BACKGROUND: Researchers have suggested that antibiotics could cure acute appendicitis. We assessed the efficacy of amoxicillin plus …
High-Dose vs Standard-Dose Amoxicillin Plus Clavulanate for Adults With Acute Sinusitis: A Randomized Clinical Trial.
Gregory J, Huynh B, Tayler B, Korgaonkar-Cherala C, Garrison G, Ata A, Sorum P. Gregory J, et al. JAMA Netw Open. 2021 Mar 1;4(3):e212713. doi: 10.1001/jamanetworkopen.2021.2713. JAMA Netw Open. 2021. PMID: 33755168 Free PMC article. Clinical Trial.
OBJECTIVE: To confirm the previous finding that high-dose amoxicillin plus clavulanate (with double the amount of amoxicillin) may be superior to standard-dose amoxicillin plus clavulanate in adults. ...INTERVENTIONS: Amoxicillin 875 mg with clavulanat …
OBJECTIVE: To confirm the previous finding that high-dose amoxicillin plus clavulanate (with double the amount of amoxicillin) …
Short Oral Antibiotic Therapy for Pediatric Febrile Urinary Tract Infections: A Randomized Trial.
Montini G, Tessitore A, Console K, Ronfani L, Barbi E, Pennesi M; STOP Trial Group. Montini G, et al. Pediatrics. 2024 Jan 1;153(1):e2023062598. doi: 10.1542/peds.2023-062598. Pediatrics. 2024. PMID: 38146260 Clinical Trial.
Secondary end points were the difference in prevalence of clinical recovery, adverse drug-related events, and resistance to amoxicillin-clavulanic acid and/or to other antibiotics when a recurrent infection occurred. ...CONCLUSIONS: This study demonstrates th …
Secondary end points were the difference in prevalence of clinical recovery, adverse drug-related events, and resistance to amoxicillin …
Prulifloxacin.
Keam SJ, Perry CM. Keam SJ, et al. Drugs. 2004;64(19):2221-34; discussion 2235-6. doi: 10.2165/00003495-200464190-00005. Drugs. 2004. PMID: 15456336 Clinical Trial.
In well designed clinical trials, good clinical and bacteriological efficacy (similar to that of ciprofloxacin, amoxicillin/clavulanic acid or pefloxacin) was seen with prulifloxacin 600 mg once daily for 10 days in patients with acute exacerbations of chroni …
In well designed clinical trials, good clinical and bacteriological efficacy (similar to that of ciprofloxacin, amoxicillin/clavul …
Amoxicillin-clavulanic acid (Augmentin).
[No authors listed] [No authors listed] Med Lett Drugs Ther. 1984 Nov 9;26(674):99-100. Med Lett Drugs Ther. 1984. PMID: 6387417 Clinical Trial. No abstract available.
Amoxicillin/clavulanic acid. An update of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Todd PA, Benfield P. Todd PA, et al. Drugs. 1990 Feb;39(2):264-307. doi: 10.2165/00003495-199039020-00008. Drugs. 1990. PMID: 2184003 Review.
Clavulanic acid enhances the antibacterial spectrum of amoxicillin by rendering most beta-lactamase-producing isolates susceptible to the drug. ...Thus, in general practice environments where beta-lactamase production has restricted the effectiveness of am …
Clavulanic acid enhances the antibacterial spectrum of amoxicillin by rendering most beta-lactamase-producing isolates …
Clinical and microbiological efficacy of moxifloxacin versus amoxicillin/clavulanic acid in severe odontogenic abscesses: a pilot study.
Al-Nawas B, Walter C, Morbach T, Seitner N, Siegel E, Maeurer M, Krummenauer F. Al-Nawas B, et al. Eur J Clin Microbiol Infect Dis. 2009 Jan;28(1):75-82. doi: 10.1007/s10096-008-0587-2. Epub 2008 Jul 29. Eur J Clin Microbiol Infect Dis. 2009. PMID: 18663500 Clinical Trial.
The mean duration until reaching the primary end point was 6.6 (range, 4.3-8.8) days in the moxifloxacin group and 6.0 (range, 3.8-8.2) days in the amoxicillin/clavulanic acid group. Median days of in-house treatment ranged between five and six days for both …
The mean duration until reaching the primary end point was 6.6 (range, 4.3-8.8) days in the moxifloxacin group and 6.0 (range, 3.8-8.2) days …
The safety of amoxicillin/clavulanic acid and cefuroxime during lactation.
Benyamini L, Merlob P, Stahl B, Braunstein R, Bortnik O, Bulkowstein M, Zimmerman D, Berkovitch M. Benyamini L, et al. Ther Drug Monit. 2005 Aug;27(4):499-502. doi: 10.1097/01.ftd.0000168294.25356.d0. Ther Drug Monit. 2005. PMID: 16044108 Clinical Trial.
The aim of our study was to evaluate the safety of 2 of the newer antibiotics, amoxicillin/clavulanic acid and cefuroxime, during lactation. Breast-feeding women who called a drug consultation center to obtain information about the potential risks of amoxi …
The aim of our study was to evaluate the safety of 2 of the newer antibiotics, amoxicillin/clavulanic acid and cefuroxi …
841 results