Antidiabetic Potential of Medicinal Plants and Their Active Components

Biomolecules. 2019 Sep 30;9(10):551. doi: 10.3390/biom9100551.

Abstract

Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health. Conventional antidiabetic drugs are effective, however, also with unavoidable side effects. On the other hand, medicinal plants may act as an alternative source of antidiabetic agents. Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. The beneficial potential of each plant matrix is given by the combined and concerted action of their profile of biologically active compounds.

Keywords: Diabetes mellitus, medicinal plants; antidiabetic; antihyperglycemic; hypoglycemic.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Blood Glucose / drug effects
  • Clinical Trials as Topic
  • Diabetes Mellitus / drug therapy*
  • Diabetes Mellitus / metabolism
  • Gene Expression Regulation / drug effects
  • Gene Regulatory Networks / drug effects
  • Humans
  • Hypoglycemic Agents / chemistry
  • Hypoglycemic Agents / pharmacology
  • Hypoglycemic Agents / therapeutic use*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Plants, Medicinal / chemistry*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Plant Extracts