Apolar Annonaceous acetogenins from the fruit pulp of Annona muricata

Alice Melot; Djibril Fall; Christophe Gleye; Pierre Champy

doi:10.3390/molecules14114387

Apolar Annonaceous acetogenins from the fruit pulp of Annona muricata

Molecules. 2009 Nov 2;14(11):4387-95. doi: 10.3390/molecules14114387.

Authors

Alice Melot¹, Djibril Fall, Christophe Gleye, Pierre Champy

Affiliation

¹ CNRS UMR 8076 BioCIS, Faculté de Pharmacie Paris-Sud 11, Châtenay-Malabry, France.

Abstract

A methylene chloride extract of the pulp of Annona muricata L. was fractionated in search for scarcely functionalized Annonaceous acetogenins (type E). Previously known C-35 and C-37 mono-epoxy unsaturated compounds, epomuricenins-A and -B (1+2) and epomusenins-A and -B (3+4), were obtained. Two new mono-epoxy saturated C-35 representatives, epomurinins-A and -B (5+6) were also isolated.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetogenins / chemistry*
Acetogenins / isolation & purification
Annona / chemistry*
Fruit / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Stereoisomerism

Substances

Acetogenins