Table 6Characteristics of Screen-Detected Invasive Cancers Diagnosed Following an Annual Versus Triennial Screening Frequency

Author, Year

Study/Trial Name

PopulationFollowupFrequencyInvasive Cancer Detection (rate per 1,000)≥Stage II (rate per 1,000)Tumor Diameter, mm (SD)Tumor >20 mm (rate per 1,000)Lymph Node Positive (rate per 1,000)Histologic Grade 3 (rate per 1,000)Poor Prognostic Index

Blamey, 2002126

UKCCCR

Women ages 50 to 62 attending a population-based screening programCumulative cancer incidence (3 years)Annual DM166/37,530 (4.4)NRNR63 (1.7)*63 (1.7)*96 (2.6)*20 (0.5)*†
Triennial DM104/38,492 (2.7)NRNR69 (1.8)*61 (1.6)*86 (2.2)*22 (0.6)*†
*

Includes both screen-detected invasive cancers and interval cancers but excludes cancers with missing information.

†

Nottingham Prognostic Index score.

Abbreviations: DM=digital mammography; mm=millimeter; NR=not reported; SD=standard deviation; UKCCR=United Kingdom Coordinating Committee on Cancer Research trial

From: Chapter 3, Results

Cover of Screening for Breast Cancer: A Comparative Effectiveness Review for the U.S. Preventive Services Task Force
Screening for Breast Cancer: A Comparative Effectiveness Review for the U.S. Preventive Services Task Force [Internet].
Evidence Synthesis, No. 231.
Henderson JT, Webber EM, Weyrich M, et al.
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