DataSet Record GDS1830: Expression Profiles Data Analysis Tools Sample Subsets
Title: Chemoresistant glioblastomas: expression profile
Cluster AnalysisGDS1830 Cluster Image
Summary: Expression analysis of cell lines derived from primary and recurrent glioblastomas with resistance to O6-alkylating agents, BCNU and TMZ. Chemoresistance to these widely-used drugs is a major obstacle to tumor treatment. Results identify a transcriptomic signature of resistance to alkylating agents.
Organism: Homo sapiens
Platform: GPL1831: SHFA
  • Bredel M, Bredel C, Juric D, Duran GE et al. Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas. J Clin Oncol 2006 Jan 10;24(2):274-87. PMID: 16365179
Reference Series: GSE2221 Sample count: 15
Value type: log2 ratio Series published: 2006/01/27