DataSet Record GDS1678: Expression Profiles Data Analysis Tools Sample Subsets
Title: Quercetin effect on hepatic cytochrome P-450 oxidoreductase null mutants
Cluster AnalysisGDS1678 Cluster Image
Summary: Analysis of cytochrome-P450 oxidoreductase (POR) null mutants at 24 hours following consumption of anti-carcinogenic flavonoid, quercetin. Results identify a diminished transcriptomic response in KO compared to WT in all tissues examined and provide insight into the bioactive nature of quercetin.
Organism: Mus musculus
Platform: GPL339: [MOE430A] Affymetrix Mouse Expression 430A Array
  • Mutch DM, Crespy V, Clough J, Henderson CJ et al. Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver. Am J Physiol Gastrointest Liver Physiol 2006 Jul;291(1):G63-72. PMID: 16455785
Reference Series: GSE4262 Sample count: 48
Value type: transformed count Series published: 2006/03/01