DataSet Record GDS1453: Expression Profiles Data Analysis Tools Sample Subsets
Title: Camptothecin effect on renal epithelial cell line and HIV transduction
Cluster AnalysisGDS1453 Cluster Image
Summary: Analysis of renal epithelial cell line 293T following treatment with 2 uM camptothecin, which boosts transduction of cells by HIV. Camptothecin induces DNA damage and arrests cell cycle at G2/M. Results provide insight into the mechanisms underlying HIV transduction boost induced by camptothecin.
Organism: Homo sapiens
Platform: GPL96: [HG-U133A] Affymetrix Human Genome U133A Array
  • Groschel B, Bushman F. Cell cycle arrest in G2/M promotes early steps of infection by human immunodeficiency virus. J Virol 2005 May;79(9):5695-704. PMID: 15827184
Reference Series: GSE2451 Sample count: 4
Value type: count Series published: 2005/05/02