Melanoma cell lines treated with a DNA methylase inhibitor
Summary:
Analysis of a poorly tumorigenic melanoma cell line and its 3 highly aggressive derivative lines after treatment with 2'-deoxy-5-azacytidine (DAC), a DNA methyltransferase inhibitor. Results suggest multiple markers for melanoma progression that are regulated by DNA methylation.
GPL80:
[Hu6800] Affymetrix Human Full Length HuGeneFL Array
Citation:
Gallagher WM, Bergin OE, Rafferty M, Kelly ZD et al. Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. Carcinogenesis 2005 Nov;26(11):1856-67. PMID: 15958521
