DataSet Record GDS1221: Expression Profiles Data Analysis Tools Sample Subsets
Title: Chronic myelogenous leukemia response to imatinib
Cluster AnalysisGDS1221 Cluster Image
Summary: Analysis of peripheral blood and bone marrow of chronic myelogenous leukemia (CML) patients prior to imatinib (Gleevec) treatment. Imatinib induces complete cytogenetic response (CCR) in most CML patients. This study attempts to determine transcriptional signature of imatinib non-responders.
Organism: Homo sapiens
Platform: GPL8300: [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
  • Crossman LC, Mori M, Hsieh YC, Lange T et al. In chronic myeloid leukemia white cells from cytogenetic responders and non-responders to imatinib have very similar gene expression signatures. Haematologica 2005 Apr;90(4):459-64. PMID: 15820940
Reference Series: GSE2535 Sample count: 28
Value type: transformed count Series published: 2005/04/18