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News: Fathers Can Pass Mitochondrial DNA to... (The Scientist) - Behind the headlines

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Media coverage of health and science topics

The Scientist Dec. 4, 2018

Fathers Can Pass Mitochondrial DNA to Children

Researchers identify unique cases in which people inherited mitochondrial DNA not just from their mother but also from their father.

Read more at The Scientist

Behind the headlines

Research findings and data from the National Library of Medicine

PubMed articles

Proc Natl Acad Sci U S A NOV. 26, 2018

Biparental Inheritance of Mitochondrial DNA in Humans

S Luo et al

Although there has been considerable debate about whether paternal mitochondrial DNA (mtDNA) transmission may coexist with maternal transmission of mtDNA, it is generally …

Science OCT. 13, 2011

Degradation of paternal mitochondria by fertilization-triggered autophagy in C. elegans embryos

M Sato et al

The mitochondrial genome is believed to be maternally inherited in many eukaryotes. Sperm-derived paternal mitochondria enter the oocyte cytoplasm upon fertilization and …

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The Scientist DEC. 12, 2018

Opinion: The Central Dogma of Mitochondrial Genetics Needs Rewriting

The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research.

The Scientist JAN. 20, 2022

Could Dad’s Mitochondrial DNA Benefit Hybrids?

Studies have found that organisms can inherit mitochondria from male parents in rare instances, and both theoretical and experimental work hint that this biparental inheritance is more than just a fluke.

The Scientist OCT. 17, 2022

Mitochondrial DNA Sneaks into Nuclear Genome

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The Scientist MARCH 1, 2018

Circulating Mitochondrial DNA Alerts Immune System to Danger

In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.

The Scientist JULY 9, 2020

New Gene Editing Tool Corrects Mutations in Mitochondrial DNA

An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.