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Ozempic seems to curb cravings for alcohol. Here's what scientists think is going on
People taking weight-loss drugs Ozempic and Wegovy report a dampening of the urge to drink. Here's how the drugs curb cravings and what that could mean for helping treat addiction.
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PubMed articles
Glucagon-like peptide 1 (GLP-1)
Since its discovery, GLP-1 has emerged as a pleiotropic hormone with a myriad of metabolic functions that go well beyond its classical identification as an incretin hormo …
Exenatide Adjunct to Nicotine Patch Facilitates Smoking Cessation and May Reduce Post-Cessation Weight Gain: A Pilot Randomized Controlled Trial
Exenatide, in combination with the NRT improved smoking abstinence, reduced craving and withdrawal symptoms, and decreased weight gain among abstainers. Findings suggest …
Liraglutide attenuates nicotine self-administration as well as nicotine seeking and hyperphagia during withdrawal in male and female rats
These findings support further studies investigating the translational potential of GLP-1R agonists to treat NUD.
Dose titration with the glucagon-like peptide-1 agonist, liraglutide, reduces cue- and drug-induced heroin seeking in high drug-taking rats
Opioid use disorder (OUD), like other substance use disorders (SUDs), is widely understood to be a disorder of persistent relapse. Despite the use of three FDA-approved m …
The glucagon-like peptide 1 analogue, exendin-4, attenuates the rewarding properties of psychostimulant drugs in mice
Glucagon-like peptide 1 (GLP-1) is an incretine hormone that controls consummatory behavior and glucose homeostasis. It is released in response to nutrient ingestion from …
Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial
BackgroundAlcohol use disorder (AUD) is a chronic, relapsing brain disorder that accounts for 5% of deaths annually, and there is an urgent need to develop new targets fo …
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Less snacking, more satisfaction: Some foods boost levels of an Ozempic-like hormone
Popular weight-loss drugs mimic GLP-1, a hormone the body makes naturally after eating. Turns out some foods trigger GLP-1 better than others, making us feel full and eat less.
Pandemic fueled alcohol abuse, especially among women, but there are treatment options | CNN
Alcohol use disorder is a growing problem in the United States, which experts say has been enhanced by the pandemic, especially among women. But as Lisa Ling reports in a new episode of “This Is Life,” scientists are exploring new treatment options.
Heart medication shows potential as treatment for alcohol use disorder
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Why aren’t there more ways to treat alcoholism?
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Alcohol Abuse Is on the Rise, but Doctors Too Often Fail to Treat It
People with alcohol use disorder are often seen in clinics and hospitals, but medical professionals too often ignore the condition.