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NCBI Databases

Literature

The World's largest repository of medical and scientific abstracts, full-text articles, books and reports

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Clusters

Sequence similarity-based protein clusters

Sparcle

Functional categorization of proteins by domain architecture

Structure

Experimentally-determined biomolecular structures

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

Probe

Sequence-based probes and primers

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

Genetics

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

Chemicals

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioSystems

Molecular pathways with links to genes, proteins and chemicals

PubChem BioAssay

Bioactivity screening studies

PubChem Compound

Chemical information with structures, information and links

PubChem Substance

Deposited substance and chemical information

BLAST

Basic Local Alignment Search Tool

BLAST is a tool for comparing an amino acid or nucleotide sequence to an entire sequence library, identifying regions of high sequence similarity.

More options

Video tutorial

VIDEO: NCBI Minute: Using organism (taxonomic) information with standalone BLAST

NCBI Minute: Using organism (taxonomic) information with standalone BLAST

Limiting a BLAST search to particular organism or taxonomic group is important for making BLAST searches efficient. This also produces results that are easier to ...

 View at YouTube

Recent videos

VIDEO: Genome Data Viewer: Analyzing Remote BAM Alignment Files and Other Tips

Genome Data Viewer: Analyzing Remote BAM Alignment Files and Other Tips

This video shows you how to upload remote BAM files, and succinctly demonstrates handy viewer settings, such as Pileup display options, and highlights the very ...

 View at YouTube

VIDEO: NCBI Minute: Running the NCBI PGAP on Your Own Data

NCBI Minute: Running the NCBI PGAP on Your Own Data

You can now download (https://github.com/ncbi/pgap) NCBI's Prokaryotic Genome Annotation Pipeline (PGAP), originally developed at NCBI for RefSeq annotations, and run it on your own machine, ...

 View at YouTube

VIDEO: NCBI Minute: Human Population Genetic Data at NCBI

NCBI Minute: Human Population Genetic Data at NCBI

Population variation frequency information can help assess the potential impact of human genetic variants. This webinar introduces you to the population variation datasets at NCBI ...

 View at YouTube