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Literature

PubMed

PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Featured Bookshelf titles

Drug Therapy for Early Rheumatoid Arthritis

A Systematic Review Update

Donahue KE, Gartlehner G, Schulman ER, et al.

Browse the Bookshelf

Literature databases

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Data

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

Structure

Experimentally-determined biomolecular structures

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein sequence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

Clinical

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

PubChem

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioAssays

Bioactivity screening studies

Compounds

Chemical information with structures, information and links

Pathways

Molecular pathways with links to genes, proteins and chemicals

Substances

Deposited substance and chemical information

News

Research news

NPR News JULY 18, 2024

A scientist took a psychedelic drug — and watched his own brain 'fall apart'

Jon Hamilton

Scientists scanned the brains of people who took psilocybin, including a member of the research team. The scans showed how the drug disrupts key networks, potentially enhancing brain plasticity.

The Washington Post JULY 15, 2024

About 7 percent of U.S. adults have had long covid, report says

Ian McMahan

Just 6 percent of the vaccinated and boosted respondents reported long covid symptoms vs. 8 percent of those who weren’t vaccinated.

NPR News JULY 14, 2024

8 things to know about the drug known as 'gas station heroin'

Bill Chappell

For decades, tianeptine was used to treat depression, even though no one knew how it worked. But it turns out it's a type of opioid, and the U.S. is facing a spike in abuse of "gas station heroin."

More news

Recent blog posts

NCBI Insights YESTERDAY

Open Access! Million Veteran Program Genome-Wide PheWAS Results Now Available in dbGaP!

The Million Veteran Program (MVP) is a research program from the U.S. Department of Veterans Affairs (VA) that has collected and analyzed health information from over one million veteran volunteers. The data include genes, lifestyles, military experiences, and exposures that may impact health and wellness.   The results of the MVP phenome-wide association study (PheWAS) … Continue reading Open Access! Million Veteran Program Genome-Wide PheWAS Results Now Available in dbGaP!

NCBI Insights JULY 18, 2024

Get Faster, More Focused Search Results with NCBI’s New BLAST Core Nucleotide Database (core_nt)

Effective August 2024, core_nt will become the default  Interested in faster nucleotide BLAST searches with more focused search results? As previously announced, NCBI has been re-evaluating the BLAST nucleotide database (nt) to make it more compact and more efficient. Thanks to your feedback, NCBI’s BLAST is excited to introduce the core nucleotide database (core_nt), an … Continue reading Get Faster, More Focused Search Results with NCBI’s New BLAST Core Nucleotide Database (core_nt)

NIH Director's Blog JULY 18, 2024

Study of Protective Gene Variant Provides Insight into Delaying Onset of Alzheimer’s Dementia

Alzheimer’s disease is currently the seventh leading cause of death in the U.S. While your likelihood of developing Alzheimer’s-related cognitive impairment increases with age, risk for this disease and age of its onset depend on many factors, including the genes you carry. An intriguing new study suggests that having just one copy of a protective gene variant may be enough to delay cognitive impairment from this devastating disease in individuals who are otherwise genetically predisposed to developing early-onset Alzheimer’s dementia. The findings, from a study supported in part by NIH and reported in The New England Journal of Medicine, offer important insights into the genetic factors and underlying pathways involved in Alzheimer’s dementia. While much more study is needed, the findings have potential implications for treatments that could one day work like this gene variant does to delay or perhaps even prevent Alzheimer’s dementia.