NCBI Databases
Literature
The World's largest repository of medical and scientific abstracts, full-text articles, books and reports
Bookshelf
Books and reports
MeSH
Ontology used for PubMed indexing
NLM Catalog
Books, journals and more in the NLM Collections
PubMed
Scientific and medical abstracts/citations
PubMed Central
Full-text journal articles
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Gene
Collected information about gene loci
GEO DataSets
Functional genomics studies
GEO Profiles
Gene expression and molecular abundance profiles
HomoloGene
Homologous genes sets for selected organisms
PopSet
Sequence sets from phylogenetic and population studies
UniGene
Clusters of expressed transcripts
Genetics
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved Domains
Conserved protein domains
Identical Protein Groups
Protein sequences grouped by identity
Protein
Protein sequences
Protein Clusters
Sequence similarity-based protein clusters
Sparcle
Functional categorization of proteins by domain architecture
Structure
Experimentally-determined biomolecular structures
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Assembly
Genome assembly information
BioCollections
Museum, herbaria, and other biorepository collections
BioProject
Biological projects providing data to NCBI
BioSample
Descriptions of biological source materials
Genome
Genome sequencing projects by organism
Nucleotide
DNA and RNA sequences
Probe
Sequence-based probes and primers
SRA
High-throughput sequence reads
Taxonomy
Taxonomic classification and nomenclature
Chemicals
Repository of chemical information, molecular pathways, and tools for bioactivity screening
BioSystems
Molecular pathways with links to genes, proteins and chemicals
PubChem BioAssay
Bioactivity screening studies
PubChem Compound
Chemical information with structures, information and links
PubChem Substance
Deposited substance and chemical information
Recent blog posts
March 15, 2019
New RefSeq annotations for big brown bat, peregrine falcon and more
In January and February, the NCBI Eukaryotic Genome Annotation Pipeline released new annotations in RefSeq for the following organisms: Aphis gossypii (cotton ...
Continue readingMarch 14, 2019
GenBank release 230 available, changes to number of files, expanded accessions
GenBank release 230.0 (2/15/2019) with 4.74 Terabases and 1.47 billion records is now available from the NCBI FTP site (flatfiles, ASN.1). There ...
Continue readingMarch 13, 2019
Follow the RNA-Seq in the Cloud hackathon on GitHub
The NCBI is in Chapel Hill, NC from March 11-13 for the “RNA-Seq in the Cloud” hackathon! We’re working hard to address ...
Continue readingBLAST
Basic Local Alignment Search Tool
BLAST is a tool for comparing an amino acid or nucleotide sequence to an entire sequence library, identifying regions of high sequence similarity.
- blastn
- Nucletide BLAST
- blastx
- Translated nucleotide vs protein database
- Primer-BLAST
- Design primers specific to your PCR template
- blastp
- Protein BLAST
- tblastn
- Protein vs translated nucleotide database
- SmartBLAST
- Find proteins highly similar to your query
Video tutorial
In this webinar, the NCBI BLAST team lead will show you how to be more effective with NCBI’s standalone BLAST applications. You will learn how ...