COVID-19 resources
Download viral genome and protein sequences, annotation and a data report
The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences
Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis
Literature
PubMed
PubMed® comprises more than 35 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.
Example searches
Search for titles, citations, identifiers and moreLiterature databases
Books and reports
Ontology used for PubMed indexing
Books, journals and more in the NLM Collections
Scientific and medical abstracts/citations
Full-text journal articles
Data
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Collected information about gene loci
Functional genomics studies
Gene expression and molecular abundance profiles
Homologous genes sets for selected organisms
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved protein domains
Protein sequences grouped by identity
Protein sequences
Models representing homologous proteins with a common function
Experimentally-determined biomolecular structures
BLAST
A tool to find regions of similarity between biological sequences
Search nucleotide sequence databases
Search protein sequence databases
Search protein databases using a translated nucleotide query
Search translated nucleotide databases using a protein query
Find primers specific to your PCR template
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Genome assembly information
Museum, herbaria, and other biorepository collections
Biological projects providing data to NCBI
Descriptions of biological source materials
Genome sequencing projects by organism
DNA and RNA sequences
High-throughput sequence reads
Taxonomic classification and nomenclature
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Privately and publicly funded clinical studies conducted around the world
Human variations of clinical significance
Genotype/phenotype interaction studies
Short genetic variations
Genome structural variation studies
Genetic testing registry
Medical genetics literature and links
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
Bioactivity screening studies
Chemical information with structures, information and links
Molecular pathways with links to genes, proteins and chemicals
Deposited substance and chemical information
News
Research news
Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?
The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.
Shaking Ordinary Ice (Very Hard) Transformed It Into Something Never Seen Before
The research illustrates how much scientists still have to learn about a molecule as simple as water.
Recent blog posts
Scrubbing human sequence contamination from Sequence Read Archive (SRA) submissions
Do you work with human-derived sequence data? Do you often struggle with the need to determine if your data is free of human sequence and therefore suitable for public distribution? We encourage submitters to screen for and remove contaminating human reads from data files prior to submission to SRA. To support investigators in this effort, … Continue reading Scrubbing human sequence contamination from Sequence Read Archive (SRA) submissions
ClinVar to offer improved support for somatic data
We need your input! ClinVar is NCBI’s archive of reports of the relationships among human genetic variations and diseases, with supporting evidence. To make ClinVar data more accurate and useful, we are introducing an enhanced data model to better accept and support classifications of somatic variants. How you can help Do you have somatic variant … Continue reading ClinVar to offer improved support for somatic data
Working to Innovate the Future of Work
NIH leadership recently gathered for its annual planning and evaluation retreat, and for the first time since late 2019, we all sat together in one large room. I cannot capture in words how inspiring and energizing it was to be together—but let me tell you, it really was! Through masks and with appropriate physical distancing, … Continue reading Working to Innovate the Future of Work