Literature
PubMed
PubMed® comprises more than 36 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.
Featured Bookshelf titles
Drug Therapy for Early Rheumatoid Arthritis
A Systematic Review Update
Clinical and Research Information on Drug-Induced Liver Injury
Literature databases
Books and reports
Ontology used for PubMed indexing
Books, journals and more in the NLM Collections
Scientific and medical abstracts/citations
Full-text journal articles
Data
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Collected information about gene loci
Functional genomics studies
Gene expression and molecular abundance profiles
Homologous genes sets for selected organisms
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved protein domains
Protein sequences grouped by identity
Protein sequences
Models representing homologous proteins with a common function
Experimentally-determined biomolecular structures
BLAST
A tool to find regions of similarity between biological sequences
Search nucleotide sequence databases
Search protein sequence databases
Search protein databases using a translated nucleotide query
Search translated nucleotide databases using a protein query
Find primers specific to your PCR template
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Genome assembly information
Museum, herbaria, and other biorepository collections
Biological projects providing data to NCBI
Descriptions of biological source materials
Genome sequencing projects by organism
DNA and RNA sequences
High-throughput sequence reads
Taxonomic classification and nomenclature
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Privately and publicly funded clinical studies conducted around the world
Human variations of clinical significance
Genotype/phenotype interaction studies
Short genetic variations
Genome structural variation studies
Genetic testing registry
Medical genetics literature and links
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
Bioactivity screening studies
Chemical information with structures, information and links
Molecular pathways with links to genes, proteins and chemicals
Deposited substance and chemical information
News
Research news
‘Zoom fatigue’ may take toll on the brain and the heart, researchers say
Participants were monitored with electroencephalogram and electrocardiogram instruments that recorded electrical activity in the brain and their heart rhythms.
Overdose deaths have soared among pregnant people, study reveals
The alarming report highlights a need to improve outreach and encourage more pregnant and postpartum people to seek treatment, experts say.
Loosening restrictions on marijuana may not be boon for reform
The Drug Enforcement Administration may remove marijuana’s classification as a Schedule I drug. It has implications for research, sales and criminal prosecutions.
Recent blog posts
Faster and Focused Searches with BLAST+ 2.15.0
New version now available Do you use NCBI’s standalone BLAST tool (BLAST+)? The latest version of BLAST+ is now available and includes two exciting new features! You can now run searches faster and focus your searches by organism more easily. What’s new? Run searches faster BLAST+ now runs 2-10x faster for small databases and … Continue reading Faster and Focused Searches with BLAST+ 2.15.0
Gene Expression Counts on NCBI RefSeq Eukaryotic Genomes
We’re rolling out exciting new features to NCBI RefSeq’s Eukaryote Genome Annotation Pipeline (EGAP)! Now you can get a better understanding of gene expression observed in different RNA-seq datasets with our newly added gene expression counts. These are determined using featureCounts based on the EGAP-produced RefSeq annotation and the set of RNA-seq runs aligned with … Continue reading Gene Expression Counts on NCBI RefSeq Eukaryotic Genomes
Gene Ontology (GO) Terms for NCBI RefSeq Eukaryotic Genomes
Are you interested in more functional information about protein-coding genes? We’ve expanded NCBI RefSeq’s Eukaryote Genome Annotation Pipeline (EGAP) to include Gene Ontology (GO) terms computed for most protein-coding genes. We are using the latest version of InterProScan, which now includes analysis based on PANTHER reference trees, on all NCBI RefSeq eukaryotic genomes. That means having … Continue reading Gene Ontology (GO) Terms for NCBI RefSeq Eukaryotic Genomes