News
Recent blog posts
New BLAST default parameters and search limits coming in September
To provide a more efficient BLAST experience for everyone, we’re changing some parameters and limits on the web BLAST service on September 8, 2020. The new settings, listed below, will improve overall performance and make search times more consistent. The …
Genes, Blood Type Tied to Risk of Severe COVID-19
Many people who contract COVID-19 have only a mild illness, or sometimes no symptoms at all. But some develop respiratory failure that requires oxygen support or even a ventilator to help them recover [1]. It’s clear that this happens more often in men than in women and more frequently in older people and those with other pre-existing chronic health conditions. But why does respiratory failure also sometimes happen to people who are young and seemingly healthy?
Graduation 2020: Tradition in the Midst of Change
Each year around this time, I’m invited to address a new group of graduates, to provide greetings and remarks at this important juncture in their lives. Over the years, I’ve sat in different parts of the commencement audience as a graduate, faculty member, parent, and speaker. It’s inspiring to listen to these speeches and a …
Research news
Oleh Hornykiewicz, Who Pioneered Treatment for Parkinson’s, Dies
The University of Toronto and University of Vienna pharmacologist developed L-dopa, a precursor to dopamine that remains the most widely used therapy for Parkinson's disease.
What Minnesota’s Protests Are Revealing About Covid-19 Spread
After George Floyd’s killing, experts warned that demonstrations could set off new waves of infections. But early testing in Minneapolis tells another story.
NCBI databases
Literature
The World's largest repository of medical and scientific abstracts, full-text articles, books and reports
Bookshelf
Books and reports
MeSH
Ontology used for PubMed indexing
NLM Catalog
Books, journals and more in the NLM Collections
PubMed
Scientific and medical abstracts/citations
PubMed Central
Full-text journal articles
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Gene
Collected information about gene loci
GEO DataSets
Functional genomics studies
GEO Profiles
Gene expression and molecular abundance profiles
HomoloGene
Homologous genes sets for selected organisms
PopSet
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved Domains
Conserved protein domains
Identical Protein Groups
Protein sequences grouped by identity
Protein
Protein sequences
Protein Clusters
Sequence similarity-based protein clusters
Sparcle
Functional categorization of proteins by domain architecture
Structure
Experimentally-determined biomolecular structures
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Assembly
Genome assembly information
BioCollections
Museum, herbaria, and other biorepository collections
BioProject
Biological projects providing data to NCBI
BioSample
Descriptions of biological source materials
Genome
Genome sequencing projects by organism
Nucleotide
DNA and RNA sequences
SRA
High-throughput sequence reads
Taxonomy
Taxonomic classification and nomenclature
Genetics
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Chemicals
Repository of chemical information, molecular pathways, and tools for bioactivity screening
BioAssays
Bioactivity screening studies
Compounds
Chemical information with structures, information and links
Pathways
Molecular pathways with links to genes, proteins and chemicals
Substances
Deposited substance and chemical information