V - Defense mechanisms

Download

Stats

COG definitions	Organims	Proteins	Median Protein Length	Genes
181	2,289	207,453	324.0	158

Organism	Protein	COG	Cat	Annotation
2016	6301	COG0251	V	Enamine deaminase RidA/Endoribonuclease Rid7C, YjgF/YER057c/UK114 family
1543	3537	COG0286	V	Type I restriction-modification system, DNA methylase subunit
1209	3101	COG0312	V O	Zn-dependent protease or N-deacetylase, PmbA/TldD/TldE family
1133	1522	COG0386	V I	Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides
2043	6339	COG0388	V	Nitrilase/amidase YafV/Nit2, hydrolyzes deaminated glutathione
1665	2528	COG0450	V	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)
2021	5714	COG0494	V	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family
1860	6458	COG0534	V	Na+-driven multidrug efflux pump, DinF/NorM/MATE family
1662	6238	COG0577	V	ABC-type antimicrobial peptide transport system, permease component
1064	1626	COG0610	V	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...
989	1405	COG0627	V	S-formylglutathione hydrolase FrmB
1632	3243	COG0693	V	Protein/nucleotide deglycase, PfpI/YajL/DJ-1 family (repair of methylglyoxal-glycated proteins and nucleic acids)
1292	2487	COG0732	V	Restriction endonuclease S subunit
1385	2701	COG0737	V F	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family
1663	1719	COG0756	V F	dUTP pyrophosphatase (dUTPase)
1659	8652	COG0841	V	Multidrug efflux pump subunit AcrB
1895	6282	COG0842	V	ABC-type multidrug transport system, permease component
1713	11708	COG0845	V M	Multidrug efflux pump subunit AcrA (membrane-fusion protein)
207	244	COG1002	V	Type II restriction/modification system, endonuclease and methylase domains
84	85	COG1059	L V	Thermostable 8-oxoguanine DNA glycosylase
2184	16983	COG1131	J V	Ribosome-associated ATPase or ATPase component of an ABC-type multidrug transport system
2159	13012	COG1132	V	ABC-type multidrug transport system, ATPase and permease component
121	121	COG1133	V	Peptide antibiotic transporter SbmA/BacA, ABC-type permease family
763	996	COG1203	V	CRISPR-Cas type I system-associated endonuclease/helicase Cas3
511	590	COG1275	V	Tellurite resistance protein TehA and related permeases
112	116	COG1332	V	CRISPR-Cas system type III CSM-effector complex subunit Csm5, RAMP superfamily Cas7 group
196	249	COG1336	V	CRISPR-Cas system type III CMR-effector complex subunit Cmr4, RAMP superfamily Cas7 group
229	467	COG1337	V	CRISPR-Cas system type III CSM-effector complex subunit Csm3, RAMP superfamily Cas7 group
685	1005	COG1343	V	CRISPR/Cas system-associated endoribonuclease Cas2
289	384	COG1353	V	CRISPR/Cas system-associated protein Cas10, large subunit of type III CRISPR-Cas systems, contains HD superfamily nuclease domain
130	142	COG1367	V	CRISPR-Cas system type III CMR-effector complex subunit Cmr1, RAMP superfamily Cas7 group
458	531	COG1401	V	5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB
1268	2515	COG1403	V	5-methylcytosine-specific restriction endonuclease McrA
67	71	COG1421	V	CRISPR-Cas system type III CSM-effector complex small subunit Csm2
53	60	COG1431	J V	PIWI domain, catalyzes dsRNA-guided hydrolysis of ssRNA, involved in RNA silencing, RNA metabolism and antiviral defense
660	883	COG1468	V	CRISPR/Cas system-associated exonuclease Cas4, RecB family
668	911	COG1479	V	DNAse/DNA nickase specific for phosphorothioated or glycosylated phage DNA, GmrSD/DndB/SspE family, contains DUF262 and HNH nuclease domains
846	2451	COG1487	V	Ribonuclease/mRNA interferase VapC, contains PIN domain
32	46	COG1517	V	CRISPR/Cas system-associated protein Csx1, contains CARF domain
1010	1527	COG1518	V	CRISPR-Cas system-associated integrase Cas1
1515	7857	COG1566	V	Multidrug resistance efflux pump EmrA
112	116	COG1567	V	CRISPR-Cas system type III CSM-effector complex subunit Csm4, RAMP superfamily Cas5 group
242	268	COG1578	V	House-cleaning carbohydrate phosphatase, DUF89 family
272	362	COG1583	V	CRISPR/Cas system endoribonuclease Cas6, RAMP superfamily
666	1916	COG1598	V	Antitoxin component HicB of the HicAB toxin-antitoxin system
172	202	COG1604	V	CRISPR/Cas system CMR subunit Cmr6, Cas7 group, RAMP superfamily
205	208	COG1659	V	Bacteriocin, linocin/CFP29 family
1533	7460	COG1680	V	CubicO group peptidase, beta-lactamase class C family
137	150	COG1688	V	CRISPR/Cas system-associated protein Cas5, RAMP superfamily
844	1020	COG1694	V	NTP pyrophosphatase, house-cleaning of non-canonical NTPs
78	80	COG1700	V	Predicted anti-virus defense system component AQ645, contains DUF2357 and PD-(D/E)xK nuclease domains
514	636	COG1715	V	Restriction endonuclease Mrr
64	105	COG1753	V	Predicted antitoxin, CopG family
1047	1916	COG1764	V	Organic hydroperoxide reductase OsmC/OhrA
110	121	COG1769	V	CRISPR-Cas system type III CMR-effector complex subunit Cmr3, RAMP superfamily Cas5 group
170	215	COG1787	V	Endonuclease, HJR/Mrr/RecB family
915	1270	COG1842	V T	Phage shock protein A, part of CBASS system
421	864	COG1848	V	VapC family ribonuclease, toxin component of the VapBC toxin-antitoxin module, contains PIN domain
141	158	COG1857	V	CRISPR-Cas system type I effector complex subunit Cas7, RAMP superfamily
203	279	COG1895	V	HEPN domain protein, predicted toxin of MNT-HEPN system
669	722	COG1912	V H	Stereoselective (R,S)-S-adenosylmethionine hydrolase (adenosine-forming)
926	1075	COG1956	V T	GAF domain-containing protein, putative methionine-R-sulfoxide reductase
308	318	COG1986	V F	Non-canonical (house-cleaning) NTP pyrophosphatase, all-alpha NTP-PPase family
577	1017	COG2002	K V	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module
684	1272	COG2026	V	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system
1236	2350	COG2076	V	Multidrug transporter EmrE and related cation transporters
959	4855	COG2124	V Q	Cytochrome P450
605	1011	COG2161	V	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family
231	592	COG2250	V	HEPN domain protein, predicted toxin of MNT-HEPN system
352	461	COG2253	V	Predicted nucleotidyltransferase component of viral defense system
31	36	COG2254	V	CRISPR/Cas system-associated endonuclease Cas3-HD
1013	1328	COG2258	V F	N-hydroxylaminopurine reductase YiiM, contains MOSC domain
1163	2673	COG2274	V	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
395	525	COG2336	V	Antitoxin component MazE of the MazEF toxin-antitoxin module
898	1574	COG2337	V	mRNA-degrading endonuclease MazF, toxin component of the MazEF toxin-antitoxin module
444	859	COG2361	V	HEPN domain protein, predicted toxin of MNT-HEPN system
854	1382	COG2367	V	Beta-lactamase class A
333	1199	COG2442	V	Predicted antitoxin component of a toxin-antitoxin system, DUF433 family
265	286	COG2602	V	Beta-lactamase class D
466	690	COG2720	V	Vancomycin resistance protein YoaR (function unknown), contains peptidoglycan-binding and VanW domains
244	276	COG2746	V	Aminoglycoside N3'-acetyltransferase
81	85	COG2810	V	Predicted type IV restriction endonuclease
381	1050	COG2849	V	Antitoxin component YwqK of the YwqJK toxin-antitoxin module
478	538	COG2914	V	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily
359	738	COG2929	V	Ribonuclease BrnT, toxin component of the BrnT-BrnA toxin-antitoxin system
191	208	COG3015	V M	Uncharacterized lipoprotein NlpE involved in copper resistance
292	421	COG3041	J V	mRNA-degrading endonuclease YafQ (mRNA interferase), toxin component of the YafQ-DinJ toxin-antitoxin module
120	154	COG3059	V	Reactive chlorine resistance protein RclC/YkgB, DUF417 family
362	614	COG3077	V	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module
765	1295	COG3093	V	Plasmid maintenance system antidote protein VapI/HigA, contains XRE-type HTH domain
213	214	COG3155	V	Glyoxalase ElbB, DJ-1 superfamily
263	283	COG3183	V	Predicted restriction endonuclease, HNH family
734	829	COG3217	V F	N-hydroxylaminopurine reductase subunit YcbX, contains MOSC domain
289	354	COG3236	V H	N-glycosidase YbiA/RibX (riboflavin biosynthesis, damage control), NADAR superfamily
47	55	COG3309	V	Virulence-associated protein VapD, endoribonuclease
88	91	COG3337	V	CRISPR-Cas system type III CMR-effector complex small subunit Cmr5
676	2601	COG3415	V	CRISPR-associated protein Csa3, CARF domain
59	65	COG3421	V	Type III restriction endonuclease
471	560	COG3440	V	Predicted restriction endonuclease
832	1481	COG3467	V	Nitroimidazole reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily
139	158	COG3510	V	Cephalosporin hydroxylase
196	203	COG3512	V	CRISPR/Cas system-associated protein Cas2
202	214	COG3513	V	CRISPR-Cas system type-II protein Cas9
279	466	COG3514	V	Antitoxin component of the BrnT-BrnA toxin-antitoxin system
466	680	COG3549	V	Plasmid maintenance system killer protein
208	258	COG3570	V	Streptomycin 6-kinase
92	109	COG3582	V	CDC48-associated ubiquitin-like protein CUZ1, contains AN1-type Zn-finger (protection from As/Sb toxicity)
293	341	COG3587	V	Restriction endonuclease, type III RM system
626	667	COG3634	V	Alkyl hydroperoxide reductase subunit AhpF
374	413	COG3649	V	CRISPR-Cas system type I effector complex subunit Cas7, RAMP superfamily
271	381	COG3657	V	Putative component of the toxin-antitoxin plasmid stabilization module
168	168	COG3725	V	Membrane protein AmpE required for beta-lactamase induction
136	210	COG3742	V	VapC family ribonuclease, contains PIN domain
366	732	COG3744	V	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)
436	491	COG3853	V	Uncharacterized conserved protein YaaN involved in tellurite resistance
100	115	COG3896	V	Chloramphenicol 3-O-phosphotransferase
88	102	COG4006	V	CRISPR-Cas system-associated protein Csm6, contains CARF domain
33	33	COG4088	J V	tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein)
567	747	COG4096	V	Type I site-specific restriction endonuclease, part of a restriction-modification system
103	123	COG4110	V	Tellurium resistance protein TerA/TerD
348	636	COG4113	V	RNA interferase (RNase) VapC, contains PIN domain
467	672	COG4115	V	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family
560	1254	COG4118	V	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor
130	131	COG4167	V	ABC-type antimicrobial peptide export system, ATPase component SapF
122	122	COG4168	V	ABC-type antimicrobial peptide export system, permease component SapB
130	130	COG4170	V	ABC-type antimicrobial peptide export system, ATPase component SapD
142	142	COG4171	V	ABC-type antimicrobial peptide export system, permease component SapC
132	208	COG4200	V	Predicted lantabiotic-exporting membrane pepmease, EfiE/EfiG/ABC2 family
293	439	COG4257	V	Streptogramin lyase
329	361	COG4268	V	5-methylcytosine-specific restriction endonuclease McrBC, regulatory subunit McrC
38	46	COG4343	V	CRISPR/Cas system-associated exonuclease Cas4, RecB family
81	103	COG4374	V	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)
169	271	COG4403	V	Lantibiotic modifying enzyme
112	156	COG4423	V	VapB family antitoxin component of VapBC type II toxin-antitoxin module
238	243	COG4452	V	Inner membrane protein CreD involved in colicin E2 resistance
195	251	COG4461	V	Lysozyme inhibitor LprI
373	530	COG4679	V X	Phage-related protein gp49, toxin component of the Tad-Ata toxin-antitoxin system
268	374	COG4680	J V	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module
145	192	COG4683	V	HigB/gp49-like toxin component of RelE/ParE type II toxin-antitoxin system
241	303	COG4691	V	Plasmid stability protein StbC1, contains ribbon-helix-helix domain
74	91	COG4734	V	Antirestriction protein ArdA
355	580	COG4767	V	Glycopeptide antibiotics resistance protein
272	345	COG4823	V	Abortive infection bacteriophage resistance protein
283	297	COG4832	V T	Cyclopropanoid cyclopropyl hydrolase, GyrI-like domain
264	634	COG4842	V	Secreted virulence factor YukE/EsxA, WXG100 family
229	269	COG4845	V	Chloramphenicol O-acetyltransferase
145	155	COG4924	V	Nuclease subunit JetD of Wadjet anti-plasmid defense system, contains DUF3322 and JetD_C (DUF2220) domains
397	546	COG5340	V	Abortive phage infection protein AbiEi, antitoxin conponent of an AbiEi-AbiEii TA system
153	254	COG5428	V	Predicted antitoxin component YuzE of a toxin-antitoxin system, DUF2283 family
237	263	COG5441	V	ATP-binding helicase-inhibiting domain, Tm-1/UPF0261 family
35	114	COG5444	V	Predicted ribonuclease, toxin component of the YeeF-YezG toxin-antitoxin module
328	481	COG5499	V	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain
129	129	COG5503	K V	DNA-dependent RNA polymerase auxiliary subunit epsilon
317	412	COG5510	V	Entericidin EcnA/EcnB
147	213	COG5551	V	CRISPR/Cas system endoribonuclease Cas6, RAMP superfamily
232	330	COG5606	V	Antitoxin component of the Tad-Ata toxin-antitoxin system, contains XRE-type HTH domain
234	269	COG5608	V	Dessication stress tolerance protein, LEA/WHy domain
241	334	COG5642	V	Predicted antitoxin component of a toxin-antitoxin system, contains Xre-type HTH domain
283	398	COG5654	V	Predicted toxin component of a toxin-antitoxin system, contains RES domain
219	234	COG5658	V	Bacterial immunity/signal transduction membrane protein SdpI, SdpI/YbgB/DUF1648 family
68	81	COG5930	V	CRISPR-Cas system type I-D effector complex large subunit Cas10d/Csc3, contains HD superfamily nuclease domain
13	14	COG5931	V	CRISPR-Cas system type-V protein Cas12a
90	100	COG5932	V	CRISPR-Cas type I-F system-associated endonuclease/helicase Cas3f, fused to Cas2 domain
92	96	COG5933	V	CRISPR-Cas system type I-F effector complex subunit Cas5f/Csy2, RAMP superfamily
235	259	COG5934	V	CRISPR-Cas system endoribonuclease Cas6e, RAMP superfamily
96	104	COG5935	V	CRISPR-Cas system endoribonuclease Cas6f/Csy4, RAMP superfamily
92	98	COG5936	V	CRISPR-Cas system type I-F effector complex subunit Cas7f/Csy3, RAMP superfamily
14	14	COG5937	V	CRISPR-Cas system type I-A effector complex large subunit Cas8a4
119	129	COG5938	V	CRISPR-Cas system type I-B effector complex large subunit Cas8b1
84	91	COG5939	V	CRISPR-Cas system type I-B effector complex large subunit Cas8b2
19	19	COG5940	V	CRISPR-Cas system type I-B effector complex large subunit Cas8b3
234	246	COG5941	V	CRISPR-Cas system type I-C effector complex large subunit Cas8c
225	246	COG5942	V	CRISPR-Cas system type I-E effector complex large subunit Cas8e
89	92	COG5943	V	CRISPR-Cas system type I-F effector complex large subunit Cas8f
43	50	COG5944	V	CRISPR-Cas system type I-G effector complex large subunit Cas8g1
59	68	COG5945	V	CRISPR-Cas system type I-G effector complex subunit Csb1, RAMP superfamily Cas7 group
59	71	COG5946	V	CRISPR-Cas system type I-G effector complex subunit Csb5, RAMP superfamily Cas5 group
69	76	COG5947	V	CRISPR-Cas system type I-D effector complex subunit Csc1, RAMP superfamily Cas5 group
78	86	COG5948	V	CRISPR-Cas system type I-D effector complex subunit Csc2, RAMP superfamily Cas7 group
225	245	COG5949	V	CRISPR-Cas system type I-E effector complex small subunit Cse2
140	162	COG5950	V	CRISPR-Cas system type II-D effector complex subunit Csx10, RAMP superfamily Cas5 group