O - Posttranslational modification, protein turnover, chaperones
Stats
COG definitions |
Organims | Proteins | Median Protein Length |
Genes |
---|---|---|---|---|
214 | 2,296 | 304,538 | 281.0 | 190 |
Organism | Protein | COG | Cat | Annotation |
---|---|---|---|---|
681 | 724 | COG0068 | O | Hydrogenase maturation factor HypF (carbamoyltransferase) |
1878 | 4327 | COG0071 | O | Small heat shock protein IbpA, HSP20 family |
301 | 352 | COG0170 | M O | Dolichol kinase |
1919 | 2785 | COG0225 | O | Peptide methionine sulfoxide reductase MsrA |
1834 | 2400 | COG0229 | O | Peptide methionine sulfoxide reductase MsrB |
2065 | 2555 | COG0234 | O | Co-chaperonin GroES (HSP10) |
2152 | 7401 | COG0265 | O | Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain |
957 | 1021 | COG0278 | O | Glutaredoxin-related protein |
676 | 830 | COG0298 | O | Hydrogenase maturation factor HybG, HypC/HupF family |
825 | 997 | COG0309 | O | Carbamoyl dehydratase HypE (hydrogenase maturation factor) |
1209 | 3101 | COG0312 | V O | Zn-dependent protease or N-deacetylase, PmbA/TldD/TldE family |
1681 | 3409 | COG0316 | O | Fe-S cluster assembly iron-binding protein IscA |
1392 | 1627 | COG0326 | O | Molecular chaperone, HSP90 family |
2050 | 5367 | COG0330 | O | Regulator of protease activity HflC, stomatin/prohibitin superfamily |
1111 | 1415 | COG0339 | O | Zn-dependent oligopeptidase, M3 family |
1161 | 1170 | COG0354 | O | Folate-binding protein YgfZ, synthesis and repair of Fe-S clusters |
713 | 822 | COG0375 | O | Hydrogenase maturation factor HypA/HybF, metallochaperone involved in Ni insertion |
1129 | 1547 | COG0378 | O | Hydrogenase/urease maturation factor HypB, Ni2+-binding GTPase |
1742 | 1811 | COG0396 | O | Fe-S cluster assembly ATPase SufC |
930 | 979 | COG0397 | O | Protein adenylyltransferase (AMPylase) SelO/YdiU (selenoprotein O) |
667 | 696 | COG0409 | O | Hydrogenase maturation factor HypD |
1436 | 2495 | COG0425 | J O H | Sulfur carrier protein TusA (tRNA thiolation, molybdenum cofactor biosynthesis) |
2221 | 4601 | COG0443 | O | Molecular chaperone DnaK (HSP70) |
2261 | 3246 | COG0459 | O | Chaperonin GroEL (HSP60 family) |
2056 | 3230 | COG0465 | O | ATP-dependent Zn proteases |
1663 | 2256 | COG0466 | O | ATP-dependent Lon protease, bacterial type |
2230 | 6029 | COG0484 | O | DnaJ molecular chaperone, contains DnaJ and DnaJ_C domains |
2240 | 5650 | COG0492 | O | Thioredoxin reductase |
1763 | 3687 | COG0501 | O | Zn-dependent protease with chaperone function |
1758 | 5226 | COG0526 | O | Thiol-disulfide isomerase or thioredoxin |
2073 | 5306 | COG0542 | O | ATP-dependent Clp protease, ATP-binding subunit ClpA |
2055 | 2178 | COG0544 | O | FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) |
1216 | 2675 | COG0545 | O | FKBP-type peptidyl-prolyl cis-trans isomerase |
2215 | 2459 | COG0576 | O | Molecular chaperone GrpE (heat shock protein HSP-70) |
1753 | 2072 | COG0606 | O | Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family |
1659 | 2674 | COG0616 | O | Periplasmic serine protease, ClpP class |
981 | 8295 | COG0625 | O | Glutathione S-transferase or stringent starvation protein SspA |
360 | 887 | COG0638 | O | 20S proteasome, alpha and beta subunits |
691 | 1233 | COG0641 | O | Sulfatase maturation enzyme AslB, radical SAM superfamily |
1983 | 4027 | COG0652 | O | Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family |
605 | 727 | COG0678 | O | Peroxiredoxin |
2079 | 2093 | COG0691 | O | tmRNA-binding protein |
1354 | 1809 | COG0694 | O | Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain |
1714 | 3219 | COG0695 | O | Glutaredoxin |
1695 | 3287 | COG0705 | O | Membrane-associated serine protease, rhomboid family |
1748 | 3376 | COG0719 | O | Fe-S cluster assembly scaffold protein SufB |
2050 | 3767 | COG0740 | O | ATP-dependent protease ClpP, protease subunit |
2182 | 2501 | COG0750 | K O | Membrane-associated protease RseP, regulator of RpoE activity |
1618 | 1940 | COG0755 | O | ABC-type transport system involved in cytochrome c biogenesis, permease component |
1676 | 4210 | COG0760 | O | Peptidyl-prolyl isomerase, parvulin family |
1172 | 1248 | COG0762 | O | Cytochrome b6 maturation protein CCB3/Ycf19 and related maturases, YggT family |
1041 | 1538 | COG0785 | O C | Cytochrome c biogenesis protein CcdA |
1868 | 4910 | COG0793 | O | C-terminal processing protease CtpA/Prc, contains a PDZ domain |
1818 | 2317 | COG0822 | O | Fe-S cluster assembly scaffold protein IscU, NifU family |
663 | 707 | COG0829 | O | Urease accessory protein UreH |
664 | 704 | COG0830 | O | Urease accessory protein UreF |
1500 | 1973 | COG0846 | O | NAD-dependent protein deacetylase, SIR2 family |
191 | 229 | COG1025 | O | Secreted/periplasmic Zn-dependent peptidases, insulinase-like |
286 | 303 | COG1026 | O | Zn-dependent peptidase, M16 (insulinase) family |
680 | 865 | COG1030 | O | Membrane-bound serine protease NfeD, ClpP class |
1131 | 1863 | COG1047 | O | Peptidyl-prolyl cis-trans isomerase, FKBP type |
714 | 903 | COG1067 | O | Predicted ATP-dependent protease |
735 | 925 | COG1076 | O | DnaJ domain-containing protein |
1584 | 2869 | COG1086 | M O | NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC |
162 | 189 | COG1123 | O | ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain |
882 | 998 | COG1138 | O C | Cytochrome c biogenesis protein CcmF |
1128 | 2457 | COG1180 | O | Pyruvate-formate lyase-activating enzyme |
1983 | 2189 | COG1219 | O | ATP-dependent protease Clp, ATPase subunit ClpX |
1201 | 1204 | COG1220 | O | ATP-dependent protease HslVU (ClpYQ), ATPase subunit HslU |
498 | 699 | COG1222 | O | ATP-dependent 26S proteasome regulatory subunit |
1990 | 7435 | COG1225 | O | Peroxiredoxin |
1206 | 3847 | COG1262 | O | Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain |
1124 | 2043 | COG1266 | O | Membrane protease YdiL, CAAX protease family |
978 | 1749 | COG1277 | O | ABC-type transport system involved in multi-copper enzyme maturation, permease component |
1234 | 1245 | COG1281 | O | Redox-regulated molecular chaperone, HSP33 family |
255 | 342 | COG1287 | O | Asparagine N-glycosylation enzyme, membrane subunit Stt3 |
836 | 863 | COG1293 | J O | Ribosome quality control (RQC) protein RqcH, Rqc2/NEMF/Tae2 family, contains fibronectin-(FbpA) and RNA- (NFACT) binding domains |
1622 | 4378 | COG1305 | O | Transglutaminase-like enzyme, putative cysteine protease |
632 | 799 | COG1310 | O | Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif |
671 | 736 | COG1333 | O C | Cytochrome c biogenesis protein ResB |
204 | 206 | COG1382 | O | Prefoldin, chaperonin cofactor |
1024 | 1039 | COG1391 | O | Glutamine synthetase adenylyltransferase |
866 | 1428 | COG1397 | O | ADP-ribosylglycohydrolase |
1432 | 5102 | COG1404 | O | Serine protease, subtilisin family |
605 | 1279 | COG1433 | O | Predicted Fe-Mo cluster-binding protein, NifX family |
1342 | 1972 | COG1477 | O H | FAD:protein FMN transferase ApbE |
894 | 1039 | COG1495 | O | Disulfide bond formation protein DsbB |
1049 | 1086 | COG1585 | O | Membrane protein implicated in regulation of membrane protease activity |
1489 | 3376 | COG1651 | O | Protein thiol-disulfide isomerase DsbC |
1947 | 11347 | COG1670 | J O | Protein N-acetyltransferase, RimJ/RimL family |
970 | 1441 | COG1703 | O | GTPase of the G3E family (not a periplasmic protein kinase) |
192 | 197 | COG1730 | O | Prefoldin subunit 5 |
821 | 1922 | COG1858 | O | Cytochrome c peroxidase |
517 | 594 | COG1899 | J O | Deoxyhypusine synthase |
207 | 258 | COG1913 | O | Archaemetzincin, Zn-dependent protease |
340 | 366 | COG1928 | O | Dolichyl-phosphate-mannose--protein O-mannosyl transferase |
50 | 50 | COG1973 | O | Hydrogenase maturation factor HypE |
1135 | 1810 | COG1975 | O | Molybdoenzyme maturation factor PaoD (Mo cofactor insertion), XdhC/CoxF family |
1330 | 1847 | COG1994 | O | Zn-dependent protease (includes sporulation protein SpoIVFB) |
1151 | 2239 | COG1999 | O | Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family |
1055 | 1726 | COG2020 | O | Protein-S-isoprenylcysteine O-methyltransferase Ste14 |
521 | 548 | COG2039 | O | Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) |
808 | 859 | COG2077 | O | Peroxiredoxin |
1339 | 1501 | COG2127 | O | ATP-dependent Clp protease adapter protein ClpS |
1553 | 1568 | COG2137 | O | SOS response regulatory protein OraA/RecX, interacts with RecA |
348 | 510 | COG2143 | O | Thioredoxin-related protein SoxW |
1411 | 2218 | COG2151 | O | Metal-sulfur cluster biosynthetic enzyme |
971 | 1063 | COG2166 | J O | Sulfur transfer protein SufE/CsdE, Fe-S cluster assembly |
739 | 1026 | COG2170 | O | Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily |
391 | 433 | COG2180 | O C P | Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor |
980 | 3008 | COG2234 | O E | Zn-dependent amino- or carboxypeptidase, M28 family |
668 | 721 | COG2317 | O | Zn-dependent carboxypeptidase, M32 family |
402 | 476 | COG2322 | O | Cytochrome oxidase assembly protein CtaM/YozB, DUF420 family |
856 | 872 | COG2332 | O C | Cytochrome c biogenesis protein CcmE |
980 | 1477 | COG2355 | O E | Zn-dependent dipeptidase, microsomal dipeptidase homolog |
1117 | 1140 | COG2360 | O | Leu/Phe-tRNA-protein transferase |
317 | 386 | COG2370 | O | Hydrogenase/urease accessory protein HupE |
559 | 594 | COG2371 | O | Urease accessory protein UreE |
841 | 850 | COG2386 | O | ABC-type transport system involved in cytochrome c biogenesis, permease component |
1390 | 2333 | COG2518 | O | Protein-L-isoaspartate O-methyltransferase |
641 | 653 | COG2738 | O | Zn-dependent membrane protease YugP |
1123 | 1576 | COG2761 | O | Predicted dithiol-disulfide isomerase, DsbA/YjbH family (virulence, stress resistance) |
1073 | 1441 | COG2825 | M O | Periplasmic chaperone for outer membrane proteins, Skp family |
1003 | 1033 | COG2844 | T O | UTP:GlnB (protein PII) uridylyltransferase |
409 | 481 | COG2846 | O | Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains |
910 | 1417 | COG2856 | O | Zn-dependent peptidase ImmA, M78 family |
538 | 543 | COG2924 | O P | Fe-S cluster biosynthesis and repair protein YggX |
689 | 694 | COG2935 | O | Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase |
730 | 731 | COG2938 | O | Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module |
489 | 491 | COG2969 | O | Stringent starvation protein B, binds SsrA peptide |
320 | 321 | COG2975 | O | Fe-S-cluster formation regulator IscX/YfhJ |
218 | 227 | COG2991 | O C | Na+-NQR maturation protein NqrM |
83 | 105 | COG2994 | O | ACP:hemolysin acyltransferase (hemolysin-activating protein) |
112 | 122 | COG2999 | O | Glutaredoxin 2 |
270 | 303 | COG3058 | O C | Formate dehydrogenase maturation protein FdhE |
229 | 239 | COG3062 | O | Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB |
716 | 790 | COG3088 | O C | Cytochrome c-type biogenesis protein CcmH/NrfF |
2205 | 6058 | COG3118 | O | Chaperedoxin CnoX, contains thioredoxin-like and TPR-like domains, YbbN/TrxSC family |
499 | 506 | COG3175 | O C | Cytochrome c oxidase assembly protein Cox11 |
676 | 903 | COG3187 | O | Heat shock protein HslJ |
698 | 725 | COG3197 | O | Cytochrome oxidase maturation protein, CcoS/FixS family |
491 | 679 | COG3212 | O | PepSY domain containing protein, regulator of zincin peptidase activity |
374 | 712 | COG3227 | O | Zn-dependent metalloprotease (Neutral protease B) |
499 | 737 | COG3336 | O C | Cytochrome c oxidase assembly protein CtaG |
726 | 955 | COG3346 | O | Cytochrome oxidase assembly protein ShyY1 |
452 | 863 | COG3381 | O | Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation |
109 | 113 | COG3389 | O | Presenilin-like membrane protease, A22 family |
424 | 441 | COG3484 | O | Predicted proteasome-type protease |
232 | 262 | COG3531 | O | Predicted protein-disulfide isomerase, contains CxxC motif |
257 | 350 | COG3555 | O | Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily |
593 | 827 | COG3590 | O | Predicted metalloendopeptidase |
495 | 841 | COG3591 | O | V8-like Glu-specific endopeptidase |
221 | 391 | COG3640 | O | CO dehydrogenase nickel-insertion accessory protein CooC1 |
319 | 489 | COG3672 | O | Predicted transglutaminase-like protein |
358 | 472 | COG3678 | O | Periplasmic chaperone Spy, Spy/CpxP family |
388 | 482 | COG3751 | J O | Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain |
322 | 332 | COG3785 | O | Heat shock protein HspQ |
294 | 296 | COG3814 | O | SspB-like protein, predicted to bind SsrA peptide |
338 | 358 | COG3823 | O | Glutamine cyclotransferase |
464 | 514 | COG3824 | O | Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain |
348 | 350 | COG3869 | O | Protein-arginine kinase McsB |
357 | 373 | COG3880 | O | Protein-arginine kinase activator protein McsA |
334 | 395 | COG3897 | O | Protein N-terminal and lysine N-methylase, NNT1/EFM7 family |
372 | 777 | COG3914 | O | Predicted O-linked N-acetylglucosamine transferase, SPINDLY family |
626 | 633 | COG4133 | O | ABC-type transport system involved in cytochrome c biogenesis, ATPase component |
1152 | 1746 | COG4232 | O | Thiol:disulfide interchange protein DsbD |
452 | 504 | COG4233 | O C | Thiol-disulfide interchange protein, contains DsbC and DsbD domains |
1045 | 1593 | COG4235 | O C | Cytochrome c-type biogenesis protein CcmH/NrfG |
504 | 541 | COG4260 | O | Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain |
41 | 42 | COG4346 | O | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase |
123 | 123 | COG4357 | O | Membrane protein assembly factor Hot13, CHY-type Zn-finger domain |
242 | 365 | COG4412 | O | Bacillopeptidase F, M6 metalloprotease family |
71 | 75 | COG4545 | O | Glutaredoxin-related protein |
94 | 95 | COG4574 | O | Serine protease inhibitor ecotin |
1572 | 6170 | COG4783 | M O | Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains |
319 | 424 | COG4826 | O | Serine protease inhibitor |
87 | 87 | COG4837 | O | Disulfide oxidoreductase YuzD |
304 | 455 | COG4870 | O | Cysteine protease, C1A family |
105 | 112 | COG4875 | O | Protein kinase association domain CaMKII_AD, NTF2-like superfamily |
181 | 199 | COG4930 | O | Predicted ATP-dependent Lon-type protease |
161 | 500 | COG4934 | O | Serine protease, subtilase family |
270 | 517 | COG4935 | O | Regulatory P domain of the subtilisin-like proprotein convertases and other proteases |
632 | 681 | COG4987 | O C | ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components |
729 | 840 | COG4988 | O C | ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components |
41 | 46 | COG5029 | O I | Prenyltransferase, beta subunit |
5 | 6 | COG5054 | O | ERV1/ALR domain, mitochondrial thiol oxidase involved in protein folding and biogenesis of Fe/S clusters |
45 | 63 | COG5078 | O | Ubiquitin-protein ligase |
51 | 51 | COG5119 | O | Sulfiredoxin, contains ParB-like CTPase domain |
19 | 19 | COG5131 | O | Ubiquitin-like protein |
4 | 4 | COG5160 | O | Protease, Ulp1 family |
5 | 8 | COG5194 | O | RING finger domain of SCF ubiquitin ligase and anaphase-promoting complex |
5 | 5 | COG5206 | O | Glycosylphosphatidylinositol transamidase (GPIT), subunit GPI8 |
528 | 550 | COG5265 | O | ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components |
21 | 24 | COG5272 | O | Ubiquitin |
295 | 449 | COG5282 | O | Zn-dependent metallopeptidase, zincin/DUF2342 superfamily |
174 | 202 | COG5331 | O I | Predicted lipid metabolism protein, MAPEG family |
75 | 103 | COG5380 | O | Lipase chaperone LimK |
271 | 271 | COG5387 | O | Mitochondrial FoF1-type ATP synthase assembly chaperone ATP12 |
1205 | 1247 | COG5405 | O | ATP-dependent protease HslVU (ClpYQ), peptidase subunit |
23 | 23 | COG5494 | O | Predicted thioredoxin/glutaredoxin |
132 | 161 | COG5513 | O | Chagasin-like inhibitor of cysteine peptidase, I42 family |
13 | 18 | COG5533 | O | Ubiquitin C-terminal hydrolase |
113 | 131 | COG5549 | O | Predicted Zn-dependent protease |
65 | 156 | COG5550 | O | Predicted aspartyl protease |
40 | 41 | COG5580 | O | Activator of HSP90 ATPase |
218 | 562 | COG5640 | O | Secreted trypsin-like serine protease |
353 | 431 | COG5646 | O P | Iron-binding protein Fra/YdhG, frataxin family (Fe-S cluster biosynthesis) |
85 | 87 | COG5661 | O | Predicted secreted Zn-dependent protease |
28 | 30 | COG5664 | O | Predicted secreted Zn-dependent protease |
74 | 74 | COG5774 | O C | Cytochrome b6 maturation protein CCB1 |
75 | 75 | COG5781 | O C | Cytochrome b6 maturation protein CCB2 |
233 | 233 | COG5818 | K D O | Stage II sporulation protein SpoIIGA (protease, processing of pro-sigma-E to active sigma-E) |
457 | 523 | COG5832 | D O | Stage IV sporulation protein SpoIVB, serine protease, degrades SpoIIQ, SpoIVFA |
133 | 143 | COG5866 | D O | Sporulation-specific protease YabG |