M - Cell wall/membrane/envelope biogenesis
Stats
| COG definitions |
Organims | Proteins | Median Protein Length |
Genes |
|---|---|---|---|---|
| 263 | 2,295 | 474,761 | 362.0 | 254 |
| Organism | Protein | COG | Cat | Annotation |
|---|---|---|---|---|
| 389 | 466 | COG0170 | M O | Dolichol kinase |
| 2114 | 5113 | COG0329 | M E | 4-hydroxy-tetrahydrodipicolinate synthase/N-acetylneuraminate lyase |
| 1354 | 1969 | COG0381 | M | UDP-N-acetylglucosamine 2-epimerase |
| 1431 | 2581 | COG0392 | M | Predicted membrane flippase AglD2/YbhN, UPF0104 family |
| 1799 | 4863 | COG0399 | M | dTDP-4-amino-4,6-dideoxygalactose transaminase |
| 303 | 347 | COG0434 | M | Membrane biogenesis protein, BtpA/SgcQ family |
| 2199 | 29426 | COG0438 | M | Lipopolysaccharide 1,6-galactosyltransferase, GT1 family |
| 2139 | 2644 | COG0449 | M | Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains |
| 2137 | 16242 | COG0451 | M | Nucleoside-diphosphate-sugar epimerase |
| 2198 | 18116 | COG0463 | M | Glycosyltransferase involved in cell wall bisynthesis |
| 1276 | 2789 | COG0464 | D T M | AAA+-type ATPase, SpoVK/Ycf46/Vps4 family |
| 2133 | 3849 | COG0472 | M | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase/archaeal AglH |
| 473 | 513 | COG0562 | M | UDP-galactopyranose mutase |
| 1604 | 3505 | COG0586 | M | Undecaprenyl phosphate translocase (flippase), DedA/Tvp38 family |
| 2033 | 2353 | COG0597 | M U | Lipoprotein signal peptidase |
| 490 | 538 | COG0615 | M | Glycerol-3-phosphate cytidylyltransferase, cytidylyltransferase family |
| 1938 | 4333 | COG0668 | M | Small-conductance mechanosensitive channel MscS |
| 1321 | 1782 | COG0677 | M | UDP-N-acetyl-D-mannosaminuronate dehydrogenase |
| 2028 | 2485 | COG0682 | M | Prolipoprotein diacylglyceryltransferase |
| 2072 | 2332 | COG0706 | M | Membrane protein insertase Oxa1/YidC/SpoIIIJ |
| 2064 | 2822 | COG0707 | M | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase |
| 1867 | 6624 | COG0726 | M G | Peptidoglycan/xylan/chitin deacetylase, PgdA/NodB/CDA1 family |
| 1617 | 1986 | COG0728 | M | Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) |
| 809 | 911 | COG0729 | M | Outer membrane translocation and assembly module TamA |
| 1817 | 5310 | COG0739 | M | Murein endopeptidase or hydrolase activator MepM/NlpD, contains LysM domain |
| 1605 | 4521 | COG0741 | M U | Soluble lytic murein transglycosylase or regulatory protein ( may contain LysM/invasin domain), , includes type III secretion system proteins IagB/IpgF/YsaH |
| 1715 | 3544 | COG0744 | M | Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase |
| 1944 | 2076 | COG0759 | M | Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ |
| 1266 | 1361 | COG0763 | M | Lipid A disaccharide synthetase |
| 2007 | 2445 | COG0766 | M | UDP-N-acetylglucosamine enolpyruvyl transferase |
| 1343 | 2384 | COG0767 | M | Permease subunit MlaE of the ABC-type intermembrane phospholipid transporter Mla |
| 2024 | 5051 | COG0768 | D M | Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) |
| 2044 | 3003 | COG0769 | M | UDP-N-acetylmuramyl tripeptide synthase |
| 2055 | 2356 | COG0770 | M | UDP-N-acetylmuramyl pentapeptide synthase |
| 2011 | 2067 | COG0771 | M | UDP-N-acetylmuramoylalanine-D-glutamate ligase |
| 2010 | 2769 | COG0773 | M | UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family |
| 1279 | 1296 | COG0774 | M | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
| 1941 | 2379 | COG0787 | M | Alanine racemase |
| 1633 | 4394 | COG0791 | M | Cell wall-associated hydrolase, NlpC_P60 family |
| 1416 | 1660 | COG0794 | M G | D-arabinose 5-phosphate isomerase GutQ |
| 1361 | 2727 | COG0795 | M N | Lipopolysaccharide export LptBFGC system, permease protein LptF |
| 1700 | 1780 | COG0796 | M | Glutamate racemase |
| 1041 | 1455 | COG0797 | M | Peptidoglycan lytic transglycosylase RlpA, contains C-terminal SPOR domain |
| 1307 | 4212 | COG0810 | M | Periplasmic protein TonB, links inner and outer membranes |
| 2026 | 2114 | COG0812 | M | UDP-N-acetylenolpyruvoylglucosamine reductase |
| 1405 | 1644 | COG0815 | M | Apolipoprotein N-acyltransferase |
| 1465 | 1698 | COG0836 | M | Mannose-1-phosphate guanylyltransferase |
| 1769 | 12148 | COG0845 | V M | Multidrug efflux pump subunit AcrA (membrane-fusion protein) |
| 1101 | 3466 | COG0859 | M | ADP-heptose:LPS heptosyltransferase |
| 1760 | 3488 | COG0860 | M | N-acetylmuramoyl-L-alanine amidase |
| 1707 | 2211 | COG1004 | M | UDP-glucose 6-dehydrogenase |
| 1325 | 1517 | COG1043 | M | Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase |
| 1464 | 1986 | COG1044 | M | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase |
| 576 | 722 | COG1083 | M | CMP-N-acetylneuraminic acid synthetase, NeuA/PseF family |
| 1586 | 2888 | COG1086 | M | NDP-sugar epimerase, includes UDP-N-acetylglucosamine 4,6-dehydratase EpsC |
| 1833 | 2387 | COG1087 | M | UDP-glucose 4-epimerase |
| 1686 | 2042 | COG1088 | M | dTDP-D-glucose 4,6-dehydratase |
| 926 | 1261 | COG1089 | M | GDP-D-mannose dehydratase |
| 1579 | 2119 | COG1091 | M | dTDP-4-dehydrorhamnose reductase |
| 1345 | 2002 | COG1127 | M | ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla |
| 2159 | 13047 | COG1132 | V M | ABC-type multidrug and LPS transport system, ATPase and permease component MsbA |
| 2224 | 10650 | COG1136 | M | ABC-type lipoprotein targeting system ATPase component LolD |
| 1352 | 1369 | COG1137 | M | ABC-type lipopolysaccharide export system, ATPase component |
| 2035 | 3485 | COG1181 | M R | D-alanine-D-alanine ligase or related ATP-grasp enzyme |
| 1996 | 2333 | COG1207 | M | Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase |
| 1564 | 3095 | COG1208 | J M | NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis protein s |
| 1723 | 2427 | COG1209 | M | dTDP-glucose pyrophosphorylase |
| 1509 | 1846 | COG1210 | M | UTP-glucose-1-phosphate uridylyltransferase |
| 1216 | 1279 | COG1212 | M | CMP-2-keto-3-deoxyoctulosonic acid synthetase |
| 1347 | 1381 | COG1286 | M F | Colicin V production accessory protein CvpA, regulator of purF expression and biofilm formation |
| 837 | 1787 | COG1292 | M | Choline-glycine betaine transporter |
| 798 | 2354 | COG1316 | M | Anionic cell wall polymer biosynthesis enzyme TagV/TagU, LytR-Cps2A-Psr (LCP) family (peptidoglycan teichoic acid transferase) |
| 672 | 795 | COG1346 | M | Putative effector of murein hydrolase |
| 816 | 1363 | COG1368 | M | Phosphoglycerol transferase MdoB/OpgB, AlkP superfamily |
| 1285 | 3635 | COG1376 | M | Lipoprotein-anchoring transpeptidase ErfK/SrfK |
| 1445 | 3242 | COG1388 | M | LysM repeat |
| 1195 | 1839 | COG1408 | M R | Phosphohydrolase of MPP superfamily, includes undecaprenyl diphosphate-linked teichoic acid hydrolase UpsH/YpbG |
| 164 | 185 | COG1422 | M | Archaeal membrane insertase Oxa1/YidC |
| 1318 | 2099 | COG1434 | M | Lipid carrier protein ElyC involved in cell wall biogenesis, DUF218 family |
| 432 | 619 | COG1442 | M | Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase |
| 1352 | 1460 | COG1452 | M | Lipopolysaccharide export system protein LptD/OstA, potential outer membrane flippase |
| 1351 | 3176 | COG1463 | M | Periplasmic subunit MlaD of the ABC-type intermembrane phospholipid transporter Mla |
| 1609 | 1642 | COG1496 | M F | UDP-MurNAc-monopeptide hydrolase/purine nucleoside phosphorylase YfiH, contains laccase domain |
| 1172 | 1295 | COG1519 | M | 3-deoxy-D-manno-octulosonic-acid transferase |
| 1254 | 3616 | COG1520 | M | Outer membrane protein assembly factor BamB, contains beta-propeller repeat |
| 1451 | 10092 | COG1538 | M | Outer membrane protein TolC |
| 1840 | 2048 | COG1559 | M | Endolytic transglycosylase MltG, terminates peptidoglycan polymerization |
| 1127 | 2593 | COG1596 | M | Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold |
| 963 | 1255 | COG1619 | M | Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling) |
| 1176 | 1179 | COG1663 | M | Tetraacyldisaccharide-1-P 4'-kinase (Lipid A 4'-kinase) |
| 1445 | 3168 | COG1686 | M | D-alanyl-D-alanine carboxypeptidase |
| 792 | 1281 | COG1696 | M | D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily |
| 1283 | 1620 | COG1704 | M | Magnetosome formation protein MamQ, lipoprotein antigen LemA family |
| 669 | 917 | COG1705 | M N | Flagellum-specific peptidoglycan hydrolase FlgJ |
| 828 | 1111 | COG1732 | M | Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) |
| 957 | 1046 | COG1778 | M R | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases |
| 762 | 971 | COG1794 | M | Amino acid racemase YgeA |
| 1318 | 3539 | COG1807 | M O | PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA |
| 13 | 23 | COG1822 | M | Uncharacterized membrane protein MJ0419, predicted role in archaeal polysaccharide biosynthesis |
| 1232 | 3378 | COG1835 | M | Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains |
| 926 | 1297 | COG1842 | V M | Phage shock protein A involved in membrane remodeling, PspA/Vipp1/IM30 family |
| 273 | 322 | COG1861 | M | Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family |
| 772 | 1126 | COG1876 | M | LD-carboxypeptidase LdcB, LAS superfamily |
| 526 | 995 | COG1887 | M I | CDP-glycerol glycerophosphotransferase, TagB/SpsB family |
| 1576 | 2171 | COG1898 | M | dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme |
| 973 | 1265 | COG1922 | M | UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family |
| 1144 | 1171 | COG1934 | M | Lipopolysaccharide export system protein LptA |
| 1384 | 1480 | COG1970 | M | Large-conductance mechanosensitive channel MscL |
| 1020 | 1272 | COG2027 | M | D-alanyl-D-alanine carboxypeptidase |
| 558 | 656 | COG2035 | M | Undecaprenyl phosphate translocase (flippase), DUF368 family |
| 372 | 391 | COG2052 | M | Regulator of extracellular matrix RemA, YlzA/DUF370 family |
| 726 | 940 | COG2089 | M | Sialic acid synthase SpsE, contains C-terminal SAF domain |
| 798 | 908 | COG2103 | M | N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase |
| 1180 | 2545 | COG2132 | D M P | Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA) |
| 1796 | 4117 | COG2148 | M | Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) |
| 584 | 653 | COG2173 | M | D-alanyl-D-alanine dipeptidase |
| 437 | 451 | COG2179 | M | Phosphatidylglycerophosphate phosphatase PgpP/YqeG or related phosphohydrolase, HAD superfamily |
| 414 | 703 | COG2194 | M | Phosphoethanolamine transferase for periplasmic glucans OpgE, AlkP superfamily |
| 572 | 808 | COG2222 | M | Fructoselysine-6-P-deglycase FrlB or related protein, duplicated sugar isomerase (SIS) domain |
| 1827 | 4937 | COG2244 | M | Membrane protein involved in the export of O-antigen and teichoic acid |
| 89 | 864 | COG2247 | M | Putative cell wall-binding domain (amidase enhancer), LytB superfamily |
| 852 | 1178 | COG2327 | M | Polysaccharide pyruvyl transferase family protein WcaK (colanic acid biosynthesis) |
| 736 | 1526 | COG2335 | M | Surface protein containing fasciclin (FAS1) repeats |
| 739 | 1084 | COG2348 | M | Lipid II:glycine glycyltransferase (Peptidoglycan interpeptide bridge formation enzyme) |
| 837 | 881 | COG2363 | M | Membrane protein YgdD, affects sensitivity to antimicrobial peptides, TMEM256/DUF423 family |
| 1052 | 1072 | COG2377 | M | 1,6-Anhydro-N-acetylmuramate kinase |
| 580 | 957 | COG2385 | D M | Sporulation protein SpoIID (lytic transglycosylase) |
| 950 | 1629 | COG2815 | M | PASTA domain, binds beta-lactams |
| 672 | 725 | COG2821 | M | Membrane-bound lytic murein transglycosylase |
| 871 | 1893 | COG2823 | M | Phospholipid-binding membrane integrity protein DolP/YraP/OsmY, contains BON domain |
| 1175 | 1755 | COG2825 | M O | Periplasmic chaperone for outer membrane proteins, Skp/HlpA/OmpH family |
| 357 | 379 | COG2829 | M | Outer membrane phospholipase A |
| 1483 | 2183 | COG2834 | M | Periplasmic chaperone for outer membrane lipoprotein sorting |
| 733 | 1029 | COG2843 | M | Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily |
| 181 | 218 | COG2845 | M | Peptidoglycan O-acetyltransferase, SGNH hydrolase family |
| 706 | 788 | COG2853 | M | Outer membrane channel MlaA of the intermembrane phospholipid transporter MlaABCDEF complex |
| 731 | 911 | COG2854 | M | Periplasmic subunit MlaC of the ABC-type intermembrane phospholipid transporter Mla |
| 251 | 258 | COG2859 | M | Outer membrane channel-forming protein BP26/OMP28, SIMPL family |
| 909 | 1954 | COG2866 | M | Murein tripeptide amidase MpaA |
| 926 | 1461 | COG2870 | M | ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase |
| 1200 | 1217 | COG2877 | M | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase |
| 1407 | 7630 | COG2885 | M | Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins |
| 776 | 775 | COG2891 | M | Cell shape-determining protein MreD |
| 1029 | 1428 | COG2908 | M | UDP-2,3-diacylglucosamine pyrophosphatase LpxH |
| 812 | 1011 | COG2913 | M | Outer membrane protein assembly factor BamE |
| 374 | 427 | COG2943 | M G | Membrane glycosyltransferase |
| 446 | 493 | COG2949 | M | Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin |
| 967 | 1675 | COG2951 | M | Membrane-bound lytic murein transglycosylase B |
| 1276 | 2710 | COG2956 | M | Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain |
| 540 | 541 | COG2980 | M | Lipopolysaccharide export system lipoprotein LptE/RlpB |
| 1025 | 2031 | COG2982 | M | Outer membrane assembly factor AsmA |
| 583 | 852 | COG2989 | M | Murein L,D-transpeptidase YcbB/YkuD |
| 470 | 799 | COG2995 | M | Intermembrane transporter PqiABC subunit PqiA |
| 430 | 536 | COG3008 | M | Intermembrane transporter PqiABC subunit PqiB |
| 401 | 448 | COG3009 | M | Intermembrane transporter PqiABC lipoprotein subunit PqiC |
| 224 | 266 | COG3015 | V M | Uncharacterized lipoprotein NlpE involved in copper resistance |
| 474 | 475 | COG3017 | M | Outer membrane lipoprotein LolB, involved in outer membrane biogenesis |
| 1145 | 1620 | COG3023 | M | N-acetyl-anhydromuramyl-L-alanine amidase AmpD |
| 621 | 802 | COG3034 | M | Murein L,D-transpeptidase YafK |
| 451 | 532 | COG3040 | M | Bacterial lipocalin Blc |
| 516 | 665 | COG3047 | M | Outer membrane protein OmpW |
| 422 | 583 | COG3049 | M R | Penicillin V acylase or related amidase, Ntn superfamily |
| 507 | 1137 | COG3055 | M | N-acetylneuraminic acid mutarotase |
| 673 | 1037 | COG3064 | M | Membrane protein TolA involved in colicin uptake |
| 181 | 247 | COG3065 | M | Starvation-inducible outer membrane lipoprotein Slp |
| 298 | 302 | COG3079 | M | Regulator of beta-lactam resistance, interacts with AlpA, YgfB/UPF0149 family |
| 208 | 239 | COG3083 | T M | Periplasmic protein PbgA/YejM, regulator of the LPS biosynthesis, AlkP superfamily |
| 387 | 396 | COG3107 | M | Outer membrane lipoprotein LpoA, binds and activates PBP1a |
| 575 | 801 | COG3108 | M | Metallopeptidase MepK/YcbK, cleaves mDAP crosslinks in peptidoglycan, peptidase M15/DUF882 family |
| 551 | 744 | COG3113 | M | MlaB (STAS domain) subunit of the ABC-type intermembrane phospholipid transporter Mla |
| 880 | 883 | COG3117 | M | Lipopolysaccharide export system protein LptC |
| 341 | 533 | COG3131 | M | Periplasmic glucan biosynthesis protein OpgG |
| 355 | 490 | COG3133 | M | Outer membrane lipoprotein SlyB |
| 504 | 646 | COG3137 | M | Putative salt-induced outer membrane protein YdiY |
| 742 | 802 | COG3164 | M | Phospholipid transporter to the outer membrane, contains AsmA2 domain |
| 556 | 2028 | COG3203 | M | Outer membrane porin OmpC/OmpF/PhoE |
| 1126 | 2790 | COG3206 | M | Tyrosine-protein kinase Wzc involved in exopolysaccharide export, GumC/Wzc1 domain |
| 628 | 879 | COG3238 | M | Membrane protein involved in production of outer membrane vehicles,YdcZ/DUF606 family |
| 191 | 229 | COG3248 | M | Nucleoside-specific outer membrane channel protein Tsx |
| 467 | 669 | COG3254 | M | L-rhamnose mutarotase |
| 1399 | 2849 | COG3264 | M | Small-conductance mechanosensitive channel MscK |
| 624 | 888 | COG3274 | M | Surface polysaccharide O-acyltransferase WecH |
| 289 | 428 | COG3306 | M | Glycosyltransferase involved in LPS biosynthesis, GR25 family |
| 1528 | 3119 | COG3307 | M | O-antigen ligase |
| 451 | 462 | COG3317 | M | Outer membrane protein assembly factor BamC |
| 928 | 2351 | COG3409 | M | Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases |
| 286 | 308 | COG3417 | M | Outer membrane lipoprotein LpoB, binds and activates PBP1b |
| 378 | 380 | COG3442 | M H | Glutaminase/glutamine amidotransferase domain of CobB, CobQ, and lipid II isoglutaminyl synthase |
| 244 | 670 | COG3468 | M U | Autotransporter adhesin AidA |
| 150 | 158 | COG3470 | M I | Uncharacterized conserved protein probably involved in high-affinity Fe2+ transport |
| 441 | 444 | COG3494 | M | UDP-2,3-diacylglucosamine hydrolase LpxI, combines lipid X-binding and nucleotide phosphodiesterase domains |
| 141 | 161 | COG3510 | V M | Rhamnose/hydroxycephalosporin O-methyltransferase, CmcI/Rv2959c family |
| 344 | 726 | COG3511 | M | Phospholipase C |
| 294 | 391 | COG3524 | M | Capsule polysaccharide export protein KpsE/RkpR |
| 248 | 281 | COG3528 | M | Lipid A deacylase LpxR, DUF2219 family |
| 236 | 281 | COG3562 | M | Capsule polysaccharide modification protein KpsS |
| 217 | 251 | COG3563 | M | Capsule polysaccharide export protein KpsC/LpsZ |
| 148 | 215 | COG3589 | M | 6-phospho-N-acetylmuramidase MupG, DUF871 family |
| 592 | 1712 | COG3637 | M | Opacity protein LomR and related surface antigens |
| 329 | 634 | COG3659 | M | Carbohydrate-selective porin OprB |
| 424 | 675 | COG3713 | M | Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family |
| 263 | 367 | COG3754 | M | Lipopolysaccharide biosynthesis protein |
| 541 | 916 | COG3757 | M | Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family |
| 600 | 1419 | COG3764 | M | Sortase (surface protein transpeptidase) |
| 187 | 262 | COG3765 | M | LPS O-antigen chain length determinant protein, WzzB/FepE family |
| 324 | 372 | COG3770 | M | Murein endopeptidase MepA (D-alanyl-D-alanine-endopeptidase) |
| 152 | 152 | COG3771 | M | Lipopolysaccharide assembly protein YciS/LapA, DUF1049 family |
| 398 | 657 | COG3772 | M | Phage-related lysozyme (muramidase), GH24 family |
| 526 | 1050 | COG3773 | D M | Cell wall hydrolase CwlJ, involved in spore germination |
| 321 | 437 | COG3774 | M | Mannosyltransferase OCH1 or related enzyme |
| 364 | 391 | COG3786 | M | L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family |
| 418 | 665 | COG3875 | M | Nickel-dependent lactate racemase |
| 556 | 661 | COG3876 | M | Exo-beta-N-acetylmuramidase YbbC/NamZ, DUF1343 family |
| 306 | 345 | COG3895 | M | Membrane-bound inhibitor of C-type lysozyme |
| 339 | 504 | COG3932 | M | Exopolysaccharide synthesis protein ExoD |
| 220 | 385 | COG3942 | M | Surface antigen |
| 457 | 748 | COG3944 | M | Capsular polysaccharide biosynthesis protein YveK |
| 33 | 34 | COG3955 | M | Uncharacterized conserved protein, DUF1919 family |
| 91 | 96 | COG3966 | M | Poly-D-alanine transfer protein DltD, involved in esterification of teichoic acids |
| 230 | 279 | COG3967 | M I | Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids |
| 347 | 376 | COG3980 | M | Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase |
| 23 | 30 | COG4092 | M | Predicted glycosyltransferase involved in capsule biosynthesis |
| 1257 | 1523 | COG4105 | M | Outer membrane protein assembly factor BamD, BamD/ComL family |
| 114 | 124 | COG4238 | M | Outer membrane murein-binding lipoprotein Lpp |
| 88 | 90 | COG4267 | M | PelG component of the PelDEFG exopolysaccharide exporter complex |
| 222 | 345 | COG4282 | M | Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4) |
| 57 | 72 | COG4305 | M | Peptidoglycan-binding domain, expansin YoaJ |
| 261 | 395 | COG4313 | M | Sphingosine uptake channel SphA-related outer membrane channel |
| 275 | 576 | COG4409 | M G | Neuraminidase (sialidase) NanH, contains C-terminal autotransporter domain |
| 244 | 400 | COG4421 | M | Predicted N-acetylglucosamine transferase involved in capsular polysaccharide biosynthesis, GT61 family |
| 348 | 577 | COG4424 | M | LPS sulfotransferase NodH |
| 234 | 357 | COG4520 | M | Surface antigen |
| 65 | 73 | COG4571 | M | Outer membrane protease |
| 39 | 42 | COG4588 | M | Accessory colonization factor AcfC, contains ABC-type periplasmic domain |
| 2035 | 6948 | COG4591 | M | ABC-type lipoprotein targeting system transmembrane component LolC/LolE |
| 663 | 1000 | COG4623 | T M | Membrane-bound lytic murein transglycosylase MltF |
| 137 | 172 | COG4678 | M X | Muramidase (phage lambda lysozyme), glycosyl transferase family 104 |
| 316 | 637 | COG4692 | M G | Predicted neuraminidase (sialidase) |
| 73 | 107 | COG4750 | M I | CTP:phosphocholine cytidylyltransferase LicC |
| 1402 | 3005 | COG4775 | M | Outer membrane protein assembly factor BamA |
| 1587 | 6318 | COG4783 | M O | Periplasmic chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains |
| 595 | 860 | COG4785 | M | Lipoprotein NlpI, contains TPR repeats |
| 333 | 381 | COG4864 | M | Flotillin-like protein FloA/YqfA, UPF0365 family |
| 468 | 1074 | COG4932 | M | Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold |
| 107 | 114 | COG4939 | M | Membrane-anchored lipoprotein Tpp15, contains FMN-binding domain |
| 1482 | 5524 | COG4948 | M R | L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily |
| 316 | 353 | COG4952 | M | L-rhamnose isomerase |
| 581 | 617 | COG4953 | M | Membrane carboxypeptidase/penicillin-binding protein PbpC |
| 1183 | 1422 | COG5009 | M | Membrane carboxypeptidase/penicillin-binding protein |
| 106 | 122 | COG5039 | M G | Exopolysaccharide biosynthesis protein EpsI, predicted pyruvyl transferase |
| 313 | 562 | COG5337 | M | Spore coat protein CotH |
| 307 | 310 | COG5375 | M | Predicted lipopolysaccharide assembly protein, LptC/YrbK-like family |
| 150 | 239 | COG5435 | M | Lipoprotein DcrB/SciW involved in osmoprotection and C1/C6 phage infection |
| 153 | 301 | COG5479 | M | LGFP repeat-containing protein, may be involved in cell wall binding |
| 308 | 604 | COG5520 | M | Glucuronoxylan xylanohydrolase XynC, GH30 family |
| 115 | 117 | COG5544 | M | Predicted membrane-modifying enzyme YfiM, lipocone superfamily |
| 179 | 181 | COG5567 | M | Periplasmic lipoprotein LptM/YifL, part of outer membrane beta-barrel assembly machinery |
| 134 | 231 | COG5577 | M | Spore coat protein CotF |
| 39 | 41 | COG5597 | M | N-acetylglucosaminyl transferase |
| 327 | 372 | COG5622 | M | Protein required for attachment to host cells |
| 216 | 349 | COG5632 | M | N-acetylmuramoyl-L-alanine amidase CwlA |
| 906 | 1114 | COG5652 | M | VanZ-like family protein, affects resistance to lipoglycopeptide antibiotics, lipocone superfamily |
| 95 | 95 | COG6142 | M | Membrane protein insertase subunit EMC6 |