Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

I - Lipid transport and metabolism

Download

Stats

COG
definitions
Organims Proteins Median Protein
Length
Genes
135 2,291 298,191 308.0 128
Organism Protein COG Cat Annotation
2224 2665 COG0020 I Undecaprenyl pyrophosphate synthase
1464 1584 COG0109 H I Polyprenyltransferase (heme O synthase)
1716 8019 COG0183 I Acetyl-CoA acetyltransferase
2046 6674 COG0204 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
2027 6874 COG0236 I Acyl carrier protein
1741 1745 COG0245 I 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
1971 4935 COG0304 I Q 3-oxoacyl-(acyl-carrier-protein) synthase
1894 12296 COG0318 I O-succinylbenzoic acid-CoA ligase MenE or related acyl-CoA synthetase (AMP-forming)
1955 2368 COG0331 I Malonyl CoA-acyl carrier protein transacylase
1927 3639 COG0332 I 3-oxoacyl-[acyl-carrier-protein] synthase III
1513 1774 COG0344 I Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase
1748 4824 COG0365 I Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase
1133 1522 COG0386 V I Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides
1563 1662 COG0416 I Acyl-ACP:phosphate acyltransferase (fatty acid/phospholipid biosynthesis)
1166 1758 COG0439 I Biotin carboxylase
1763 2598 COG0511 I Biotin carboxyl carrier protein
2074 3825 COG0558 I Phosphatidylglycerophosphate synthase
1936 1941 COG0575 I CDP-diglyceride synthetase
1755 3712 COG0584 I Glycerophosphoryl diester phosphodiesterase
1426 1859 COG0623 I Enoyl-[acyl-carrier-protein] reductase FabI
1495 5312 COG0657 I Acetyl esterase/lipase
1572 2692 COG0671 I Membrane-associated phospholipid phosphatase
1445 1611 COG0688 I Phosphatidylserine decarboxylase
1520 1595 COG0736 I Phosphopantetheinyl transferase (holo-ACP synthase)
1706 1716 COG0743 I 1-deoxy-D-xylulose 5-phosphate reductoisomerase
1754 1860 COG0761 I 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH
1744 3027 COG0764 I 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase
1642 1810 COG0777 I Acetyl-CoA carboxylase beta subunit
1190 1281 COG0818 I Diacylglycerol kinase
1743 1767 COG0821 I 4-hydroxy-3-methylbut-2-enyl diphosphate synthase IspG/GcpE
1835 4887 COG0824 I Acyl-CoA thioesterase FadM
1639 1702 COG0825 I Acetyl-CoA carboxylase alpha subunit
2054 15641 COG1012 I Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase
1247 2311 COG1022 I Long-chain acyl-CoA synthetase (AMP-forming)
1613 12722 COG1024 I Enoyl-CoA hydratase/carnithine racemase
2182 35316 COG1028 I NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family
902 1759 COG1075 I Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold
1794 1913 COG1154 H I Deoxyxylulose-5-phosphate synthase
1389 1724 COG1183 I Phosphatidylserine synthase
1766 1940 COG1211 I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
350 417 COG1213 I Choline kinase
1556 4679 COG1250 I 3-hydroxyacyl-CoA dehydrogenase
561 612 COG1257 I Hydroxymethylglutaryl-CoA reductase
452 534 COG1260 I Myo-inositol-1-phosphate synthase
996 1060 COG1267 I Phosphatidylglycerophosphatase A
1328 2098 COG1304 C I R FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase
627 1723 COG1307 I Fatty acid-binding protein DegV
633 985 COG1398 I Fatty-acid desaturase
920 1124 COG1443 I Isopentenyldiphosphate isomerase
582 646 COG1461 I Fatty acid kinase
1817 3931 COG1502 I Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase
1295 2069 COG1560 I Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis)
1184 1867 COG1562 I Phytoene/squalene synthetase
475 745 COG1577 I Mevalonate kinase
1446 2632 COG1597 I R Phosphatidylglycerol kinase, diacylglycerol kinase family
1307 2033 COG1607 I Acyl-CoA hydrolase
197 202 COG1608 I Isopentenyl phosphate kinase
398 430 COG1646 I Glycerol-1-phosphate heptaprenyltransferase
380 642 COG1657 I Terpene cyclase SqhC
229 254 COG1679 I Mevalonate 5-phosphate dehydratase subunit 1, aconitase superfamily (modified mevalonate pathway)
230 250 COG1786 I Mevalonate 5-phosphate dehydratase subunit 2, swiveling domain (modified mevalonate pathway)
1010 1572 COG1788 I Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
1054 4585 COG1804 I Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases
1055 2230 COG1884 I Methylmalonyl-CoA mutase, N-terminal domain/subunit
526 995 COG1887 M I CDP-glycerol glycerophosphotransferase, TagB/SpsB family
508 996 COG1924 I Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)
666 1106 COG1946 I Acyl-CoA thioesterase
1797 1809 COG1947 I 4-diphosphocytidyl-2C-methyl-D-erythritol kinase
1716 16245 COG1960 I Acyl-CoA dehydrogenase related to the alkylation response protein AidB
280 313 COG1964 H I Archaeal tetraether lipid synthase/C-terminal domain of the GTP 3',8'-cyclase MoaA, radical SAM superfamily
1993 2211 COG1968 I Undecaprenyl pyrophosphate phosphatase
1256 4755 COG2030 I Acyl-CoA dehydratase PaaZ
274 309 COG2031 I Short chain fatty acids transporter
1018 1593 COG2057 I Acyl-CoA:acetate/3-ketoacid CoA transferase, beta subunit
890 1768 COG2067 I Long-chain fatty acid transport protein
101 119 COG2074 G I 2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase
1460 3784 COG2084 I 3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase
95 105 COG2134 I CDP-diacylglycerol pyrophosphatase
1095 2026 COG2185 I Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
1416 3369 COG2230 I Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases
1220 1853 COG2246 I Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)
1679 4268 COG2267 I Lysophospholipase, alpha-beta hydrolase superfamily
464 963 COG2272 I Carboxylesterase type B
1147 3843 COG2303 I R Choline dehydrogenase or related flavoprotein
323 334 COG2324 I Carotenoid 2',3'-hydratase CruF
1761 7055 COG2755 D I Lysophospholipase L1 or related esterase. Includes spore coat protein LipC/YcsK
476 616 COG2898 I Bifunctional lysylphosphatidylglycerol synthetase/flippase MprF
453 566 COG2930 I Phosphatidylinositol-binding SYLF domain, Ysc84/FYVE family
376 423 COG2937 I Glycerol-3-phosphate O-acyltransferase
796 1877 COG3000 I Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily
243 251 COG3007 I Trans-2-enoyl-CoA reductase
374 376 COG3124 I Acyl carrier protein phosphodiesterase
949 2172 COG3239 I Fatty acid desaturase
290 424 COG3240 I Phospholipase/lecithinase/hemolysin, may have acyltransferase activity
663 1311 COG3243 I Poly-beta-hydroxybutyrate synthase
496 722 COG3255 I Putative sterol carrier protein, contains SCP2 domain
118 121 COG3356 I Predicted membrane-associated lipid hydrolase, neutral ceramidase superfamily
356 371 COG3407 I Mevalonate pyrophosphate decarboxylase
441 526 COG3425 I 3-hydroxy-3-methylglutaryl CoA synthase
266 375 COG3433 I Q Acyl carrier protein/domain
150 158 COG3470 M I Uncharacterized conserved protein probably involved in high-affinity Fe2+ transport
174 272 COG3475 I Phosphorylcholine metabolism protein LicD
268 358 COG3675 I Predicted lipase
159 172 COG3697 H I Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)
435 465 COG3714 I Membrane lysoplasmalogenase (glycerophospholipid hydrolase), YhhN family
210 263 COG3777 I Hydroxyacyl-ACP dehydratase HTD2, hotdog domain
982 3937 COG3832 I Chalcone/flavanone-binding protein YndB, AHSA1/START/SRPBCC domain
190 226 COG3882 I Predicted enzyme involved in methoxymalonyl-ACP biosynthesis
324 346 COG3884 I Acyl-ACP thioesterase
13 13 COG3890 I Phosphomevalonate kinase
375 472 COG3963 I Phosphatidylethanolamine N-methyltransferase
230 279 COG3967 M I Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids
229 243 COG4247 I 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
223 227 COG4281 I Acyl-CoA-binding protein
608 738 COG4395 I Predicted lipid-binding transport protein, Tim44 family
220 233 COG4539 I 2-hydroxy fatty acid dioxygenase MPO1 (alpha-oxidation of fatty acids)
343 410 COG4553 I Poly-beta-hydroxyalkanoate depolymerase
432 514 COG4667 I Predicted phospholipase, patatin/cPLA2 family
349 468 COG4670 I Acyl CoA:acetate/3-ketoacid CoA transferase
235 385 COG4677 G I Pectin methylesterase and related acyl-CoA thioesterases
281 306 COG4706 I Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain
73 107 COG4750 M I CTP:phosphocholine cytidylyltransferase LicC
1868 3964 COG4770 I Acetyl/propionyl-CoA carboxylase, alpha subunit
137 148 COG4781 I Membrane-anchored glycerophosphoryl diester phosphodiesterase (GDPDase), membrane domain
1396 3026 COG4799 I Acetyl-CoA carboxylase, carboxyltransferase component
310 370 COG4850 I Phosphatidate phosphatase APP1
346 401 COG4894 I Putative phospholipid scramblase YxjI, Tubby2 superfamily
66 68 COG4981 I Enoyl reductase domain of yeast-type fatty acid synthase
51 53 COG4982 I 3-oxoacyl-ACP reductase domain of yeast-type fatty acid synthase FAS1
95 166 COG5029 O I Prenyltransferase, beta subunit
79 82 COG5050 I sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases
25 26 COG5083 I Phosphatidate phosphatase PAH1, contains Lipin and LNS2 domains. can be involved in plasmid maintenance
53 57 COG5274 C I Cytochrome b involved in lipid metabolism
178 215 COG5331 O I Predicted lipid metabolism protein, MAPEG family
169 179 COG5379 I S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase