I - Lipid transport and metabolism
Stats
| COG definitions |
Organims | Proteins | Median Protein Length |
Genes |
|---|---|---|---|---|
| 135 | 2,291 | 298,191 | 308.0 | 128 |
| Organism | Protein | COG | Cat | Annotation |
|---|---|---|---|---|
| 2224 | 2665 | COG0020 | I | Undecaprenyl pyrophosphate synthase |
| 1464 | 1584 | COG0109 | H I | Polyprenyltransferase (heme O synthase) |
| 1716 | 8019 | COG0183 | I | Acetyl-CoA acetyltransferase |
| 2046 | 6674 | COG0204 | I | 1-acyl-sn-glycerol-3-phosphate acyltransferase |
| 2027 | 6874 | COG0236 | I | Acyl carrier protein |
| 1741 | 1745 | COG0245 | I | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| 1971 | 4935 | COG0304 | I Q | 3-oxoacyl-(acyl-carrier-protein) synthase |
| 1894 | 12296 | COG0318 | I | O-succinylbenzoic acid-CoA ligase MenE or related acyl-CoA synthetase (AMP-forming) |
| 1955 | 2368 | COG0331 | I | Malonyl CoA-acyl carrier protein transacylase |
| 1927 | 3639 | COG0332 | I | 3-oxoacyl-[acyl-carrier-protein] synthase III |
| 1513 | 1774 | COG0344 | I | Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase |
| 1748 | 4824 | COG0365 | I | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase |
| 1133 | 1522 | COG0386 | V I | Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides |
| 1563 | 1662 | COG0416 | I | Acyl-ACP:phosphate acyltransferase (fatty acid/phospholipid biosynthesis) |
| 1166 | 1758 | COG0439 | I | Biotin carboxylase |
| 1763 | 2598 | COG0511 | I | Biotin carboxyl carrier protein |
| 2074 | 3825 | COG0558 | I | Phosphatidylglycerophosphate synthase |
| 1936 | 1941 | COG0575 | I | CDP-diglyceride synthetase |
| 1755 | 3712 | COG0584 | I | Glycerophosphoryl diester phosphodiesterase |
| 1426 | 1859 | COG0623 | I | Enoyl-[acyl-carrier-protein] reductase FabI |
| 1495 | 5312 | COG0657 | I | Acetyl esterase/lipase |
| 1572 | 2692 | COG0671 | I | Membrane-associated phospholipid phosphatase |
| 1445 | 1611 | COG0688 | I | Phosphatidylserine decarboxylase |
| 1520 | 1595 | COG0736 | I | Phosphopantetheinyl transferase (holo-ACP synthase) |
| 1706 | 1716 | COG0743 | I | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| 1754 | 1860 | COG0761 | I | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH |
| 1744 | 3027 | COG0764 | I | 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase |
| 1642 | 1810 | COG0777 | I | Acetyl-CoA carboxylase beta subunit |
| 1190 | 1281 | COG0818 | I | Diacylglycerol kinase |
| 1743 | 1767 | COG0821 | I | 4-hydroxy-3-methylbut-2-enyl diphosphate synthase IspG/GcpE |
| 1835 | 4887 | COG0824 | I | Acyl-CoA thioesterase FadM |
| 1639 | 1702 | COG0825 | I | Acetyl-CoA carboxylase alpha subunit |
| 2054 | 15641 | COG1012 | I | Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase |
| 1247 | 2311 | COG1022 | I | Long-chain acyl-CoA synthetase (AMP-forming) |
| 1613 | 12722 | COG1024 | I | Enoyl-CoA hydratase/carnithine racemase |
| 2182 | 35316 | COG1028 | I | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family |
| 902 | 1759 | COG1075 | I | Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold |
| 1794 | 1913 | COG1154 | H I | Deoxyxylulose-5-phosphate synthase |
| 1389 | 1724 | COG1183 | I | Phosphatidylserine synthase |
| 1766 | 1940 | COG1211 | I | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
| 350 | 417 | COG1213 | I | Choline kinase |
| 1556 | 4679 | COG1250 | I | 3-hydroxyacyl-CoA dehydrogenase |
| 561 | 612 | COG1257 | I | Hydroxymethylglutaryl-CoA reductase |
| 452 | 534 | COG1260 | I | Myo-inositol-1-phosphate synthase |
| 996 | 1060 | COG1267 | I | Phosphatidylglycerophosphatase A |
| 1328 | 2098 | COG1304 | C I R | FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase |
| 627 | 1723 | COG1307 | I | Fatty acid-binding protein DegV |
| 633 | 985 | COG1398 | I | Fatty-acid desaturase |
| 920 | 1124 | COG1443 | I | Isopentenyldiphosphate isomerase |
| 582 | 646 | COG1461 | I | Fatty acid kinase |
| 1817 | 3931 | COG1502 | I | Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase |
| 1295 | 2069 | COG1560 | I | Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) |
| 1184 | 1867 | COG1562 | I | Phytoene/squalene synthetase |
| 475 | 745 | COG1577 | I | Mevalonate kinase |
| 1446 | 2632 | COG1597 | I R | Phosphatidylglycerol kinase, diacylglycerol kinase family |
| 1307 | 2033 | COG1607 | I | Acyl-CoA hydrolase |
| 197 | 202 | COG1608 | I | Isopentenyl phosphate kinase |
| 398 | 430 | COG1646 | I | Glycerol-1-phosphate heptaprenyltransferase |
| 380 | 642 | COG1657 | I | Terpene cyclase SqhC |
| 229 | 254 | COG1679 | I | Mevalonate 5-phosphate dehydratase subunit 1, aconitase superfamily (modified mevalonate pathway) |
| 230 | 250 | COG1786 | I | Mevalonate 5-phosphate dehydratase subunit 2, swiveling domain (modified mevalonate pathway) |
| 1010 | 1572 | COG1788 | I | Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit |
| 1054 | 4585 | COG1804 | I | Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases |
| 1055 | 2230 | COG1884 | I | Methylmalonyl-CoA mutase, N-terminal domain/subunit |
| 526 | 995 | COG1887 | M I | CDP-glycerol glycerophosphotransferase, TagB/SpsB family |
| 508 | 996 | COG1924 | I | Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) |
| 666 | 1106 | COG1946 | I | Acyl-CoA thioesterase |
| 1797 | 1809 | COG1947 | I | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase |
| 1716 | 16245 | COG1960 | I | Acyl-CoA dehydrogenase related to the alkylation response protein AidB |
| 280 | 313 | COG1964 | H I | Archaeal tetraether lipid synthase/C-terminal domain of the GTP 3',8'-cyclase MoaA, radical SAM superfamily |
| 1993 | 2211 | COG1968 | I | Undecaprenyl pyrophosphate phosphatase |
| 1256 | 4755 | COG2030 | I | Acyl-CoA dehydratase PaaZ |
| 274 | 309 | COG2031 | I | Short chain fatty acids transporter |
| 1018 | 1593 | COG2057 | I | Acyl-CoA:acetate/3-ketoacid CoA transferase, beta subunit |
| 890 | 1768 | COG2067 | I | Long-chain fatty acid transport protein |
| 101 | 119 | COG2074 | G I | 2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase |
| 1460 | 3784 | COG2084 | I | 3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase |
| 95 | 105 | COG2134 | I | CDP-diacylglycerol pyrophosphatase |
| 1095 | 2026 | COG2185 | I | Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) |
| 1416 | 3369 | COG2230 | I | Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases |
| 1220 | 1853 | COG2246 | I | Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose) |
| 1679 | 4268 | COG2267 | I | Lysophospholipase, alpha-beta hydrolase superfamily |
| 464 | 963 | COG2272 | I | Carboxylesterase type B |
| 1147 | 3843 | COG2303 | I R | Choline dehydrogenase or related flavoprotein |
| 323 | 334 | COG2324 | I | Carotenoid 2',3'-hydratase CruF |
| 1761 | 7055 | COG2755 | D I | Lysophospholipase L1 or related esterase. Includes spore coat protein LipC/YcsK |
| 476 | 616 | COG2898 | I | Bifunctional lysylphosphatidylglycerol synthetase/flippase MprF |
| 453 | 566 | COG2930 | I | Phosphatidylinositol-binding SYLF domain, Ysc84/FYVE family |
| 376 | 423 | COG2937 | I | Glycerol-3-phosphate O-acyltransferase |
| 796 | 1877 | COG3000 | I | Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily |
| 243 | 251 | COG3007 | I | Trans-2-enoyl-CoA reductase |
| 374 | 376 | COG3124 | I | Acyl carrier protein phosphodiesterase |
| 949 | 2172 | COG3239 | I | Fatty acid desaturase |
| 290 | 424 | COG3240 | I | Phospholipase/lecithinase/hemolysin, may have acyltransferase activity |
| 663 | 1311 | COG3243 | I | Poly-beta-hydroxybutyrate synthase |
| 496 | 722 | COG3255 | I | Putative sterol carrier protein, contains SCP2 domain |
| 118 | 121 | COG3356 | I | Predicted membrane-associated lipid hydrolase, neutral ceramidase superfamily |
| 356 | 371 | COG3407 | I | Mevalonate pyrophosphate decarboxylase |
| 441 | 526 | COG3425 | I | 3-hydroxy-3-methylglutaryl CoA synthase |
| 266 | 375 | COG3433 | I Q | Acyl carrier protein/domain |
| 150 | 158 | COG3470 | M I | Uncharacterized conserved protein probably involved in high-affinity Fe2+ transport |
| 174 | 272 | COG3475 | I | Phosphorylcholine metabolism protein LicD |
| 268 | 358 | COG3675 | I | Predicted lipase |
| 159 | 172 | COG3697 | H I | Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) |
| 435 | 465 | COG3714 | I | Membrane lysoplasmalogenase (glycerophospholipid hydrolase), YhhN family |
| 210 | 263 | COG3777 | I | Hydroxyacyl-ACP dehydratase HTD2, hotdog domain |
| 982 | 3937 | COG3832 | I | Chalcone/flavanone-binding protein YndB, AHSA1/START/SRPBCC domain |
| 190 | 226 | COG3882 | I | Predicted enzyme involved in methoxymalonyl-ACP biosynthesis |
| 324 | 346 | COG3884 | I | Acyl-ACP thioesterase |
| 13 | 13 | COG3890 | I | Phosphomevalonate kinase |
| 375 | 472 | COG3963 | I | Phosphatidylethanolamine N-methyltransferase |
| 230 | 279 | COG3967 | M I | Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids |
| 229 | 243 | COG4247 | I | 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) |
| 223 | 227 | COG4281 | I | Acyl-CoA-binding protein |
| 608 | 738 | COG4395 | I | Predicted lipid-binding transport protein, Tim44 family |
| 220 | 233 | COG4539 | I | 2-hydroxy fatty acid dioxygenase MPO1 (alpha-oxidation of fatty acids) |
| 343 | 410 | COG4553 | I | Poly-beta-hydroxyalkanoate depolymerase |
| 432 | 514 | COG4667 | I | Predicted phospholipase, patatin/cPLA2 family |
| 349 | 468 | COG4670 | I | Acyl CoA:acetate/3-ketoacid CoA transferase |
| 235 | 385 | COG4677 | G I | Pectin methylesterase and related acyl-CoA thioesterases |
| 281 | 306 | COG4706 | I | Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain |
| 73 | 107 | COG4750 | M I | CTP:phosphocholine cytidylyltransferase LicC |
| 1868 | 3964 | COG4770 | I | Acetyl/propionyl-CoA carboxylase, alpha subunit |
| 137 | 148 | COG4781 | I | Membrane-anchored glycerophosphoryl diester phosphodiesterase (GDPDase), membrane domain |
| 1396 | 3026 | COG4799 | I | Acetyl-CoA carboxylase, carboxyltransferase component |
| 310 | 370 | COG4850 | I | Phosphatidate phosphatase APP1 |
| 346 | 401 | COG4894 | I | Putative phospholipid scramblase YxjI, Tubby2 superfamily |
| 66 | 68 | COG4981 | I | Enoyl reductase domain of yeast-type fatty acid synthase |
| 51 | 53 | COG4982 | I | 3-oxoacyl-ACP reductase domain of yeast-type fatty acid synthase FAS1 |
| 95 | 166 | COG5029 | O I | Prenyltransferase, beta subunit |
| 79 | 82 | COG5050 | I | sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases |
| 25 | 26 | COG5083 | I | Phosphatidate phosphatase PAH1, contains Lipin and LNS2 domains. can be involved in plasmid maintenance |
| 53 | 57 | COG5274 | C I | Cytochrome b involved in lipid metabolism |
| 178 | 215 | COG5331 | O I | Predicted lipid metabolism protein, MAPEG family |
| 169 | 179 | COG5379 | I | S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase |