Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

G - Carbohydrate transport and metabolism

Download

Stats

COG
definitions
Organims Proteins Median Protein
Length
Genes
259 2,294 410,876 366.0 242
Organism Protein COG Cat Annotation
1689 2107 COG0021 G Transketolase
714 731 COG0033 G Phosphoglucomutase/phosphomannomutase
2098 2392 COG0036 G Pentose-5-phosphate-3-epimerase
2241 3633 COG0057 G Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
1312 1815 COG0058 G Glucan phosphorylase
1177 1222 COG0120 G Ribose 5-phosphate isomerase
2232 2301 COG0126 G 3-phosphoglycerate kinase
1889 3508 COG0129 G E Dihydroxyacid dehydratase/phosphogluconate dehydratase
2218 2409 COG0148 G Enolase
2243 2489 COG0149 G Triosephosphate isomerase
884 1019 COG0153 G Galactokinase
889 973 COG0158 G Fructose-1,6-bisphosphatase
2134 2323 COG0166 G Glucose-6-phosphate isomerase
1857 2431 COG0176 G Transaldolase/fructose-6-phosphate aldolase
1707 2542 COG0191 G Fructose/tagatose bisphosphate aldolase
1604 2507 COG0205 G 6-phosphofructokinase
1584 3103 COG0235 G E 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation)
831 1466 COG0246 G Mannitol-1-phosphate/altronate dehydrogenases
353 448 COG0269 G 3-keto-L-gulonate-6-phosphate decarboxylase
990 1317 COG0279 G Phosphoheptose isomerase
1352 2419 COG0296 G 1,4-alpha-glucan branching enzyme
1219 1474 COG0297 G Glycogen synthase
939 979 COG0362 G 6-phosphogluconate dehydrogenase
1546 2328 COG0363 G 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
1345 1720 COG0364 G Glucose-6-phosphate 1-dehydrogenase
1563 5843 COG0366 G Glycosidase/amylase (phosphorylase)
788 915 COG0380 G Trehalose-6-phosphate synthase, GT20 family
436 715 COG0383 G Alpha-mannosidase
1018 1175 COG0391 G H Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family
1275 9875 COG0395 G ABC-type glycerol-3-phosphate transport system, permease component
1834 5437 COG0406 G Broad specificity phosphatase PhoE
1115 1588 COG0448 G Glucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase)
2067 2541 COG0469 G Pyruvate kinase
1261 2728 COG0471 G Di- and tricarboxylate antiporter
846 2343 COG0477 G E P R MFS family permease, includes anhydromuropeptide permease AmpG
1844 3774 COG0483 G Archaeal fructose-1,6-bisphosphatase or related enzyme, inositol monophosphatase family
2081 8020 COG0524 G Sugar or nucleoside kinase, ribokinase family
1828 3187 COG0574 G Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
1147 1469 COG0579 G L-2-hydroxyglutarate oxidase LhgO
1181 1729 COG0580 G Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family)
955 1028 COG0588 G Phosphoglycerate mutase (BPG-dependent)
1767 4143 COG0637 G Beta-phosphoglucomutase, HAD superfamily
1708 3917 COG0662 G Mannose-6-phosphate isomerase, cupin superfamily
384 391 COG0676 G D-hexose-6-phosphate mutarotase
1322 1384 COG0696 G Phosphoglycerate mutase (BPG-independent), AlkP superfamily
2068 13867 COG0697 G E R Permease of the drug/metabolite transporter (DMT) superfamily
1378 1866 COG0698 G Ribose 5-phosphate isomerase RpiB
1852 6321 COG0726 M G Peptidoglycan/xylan/chitin deacetylase, PgdA/NodB/CDA1 family
978 2103 COG0738 G Fucose permease
1416 1660 COG0794 M G D-arabinose 5-phosphate isomerase GutQ
1267 1911 COG0800 G 2-keto-3-deoxy-6-phosphogluconate aldolase
726 830 COG0837 G Glucokinase
688 763 COG1015 G Phosphopentomutase
593 645 COG1023 G 6-phosphogluconate dehydrogenase (decarboxylating)
1236 2613 COG1064 G D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family
470 601 COG1069 G Ribulose kinase
1279 3395 COG1070 G Sugar (pentulose or hexulose) kinase
1229 1621 COG1080 G Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
1417 7110 COG1082 G Sugar phosphate isomerase/epimerase
782 883 COG1085 G Galactose-1-phosphate uridylyltransferase
873 1232 COG1105 G 1-phosphofructokinase or 6-phosphofructokinase II
2235 5304 COG1109 G Phosphomannomutase
1006 4574 COG1129 G ABC-type sugar transport system, ATPase component
1277 1861 COG1134 G ABC-type polysaccharide/polyol phosphate transport system, ATPase component
967 5412 COG1172 G Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component
1319 9617 COG1175 G ABC-type sugar transport system, permease component
1631 5950 COG1216 G Glycosyltransferase, GT2 family
538 2197 COG1263 G Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
552 2258 COG1264 G Phosphotransferase system IIB components
519 862 COG1299 G Phosphotransferase system, fructose-specific IIC component
542 766 COG1312 G D-mannonate dehydratase
1254 4012 COG1349 K G DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family
944 1662 COG1363 G E Putative aminopeptidase FrvX
266 698 COG1440 G Phosphotransferase system cellobiose-specific component IIB
508 841 COG1445 G Phosphotransferase system fructose-specific component IIB
244 562 COG1447 G Phosphotransferase system cellobiose-specific component IIA
495 715 COG1449 G Alpha-amylase/alpha-mannosidase, GH57 family
304 894 COG1455 G Phosphotransferase system cellobiose-specific component IIC
1716 4403 COG1472 G Periplasmic beta-glucosidase and related glycosidases
904 1223 COG1482 G Mannose-6-phosphate isomerase, class I
449 906 COG1486 G Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase
769 783 COG1489 T G DNA-binding protein, stimulates sugar fermentation
897 966 COG1494 G Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein
754 1400 COG1501 G Alpha-glucosidase/xylosidase, GH31 family
1048 1742 COG1523 G Pullulanase/glycogen debranching enzyme
301 330 COG1543 G Predicted glycosyl hydrolase, contains GH57 and DUF1957 domains
573 846 COG1554 G Phosphatase/phosphodiesterase/kojibiose phosphorylase YcjT/PafA/Npp1, AlkP superfamily
898 4195 COG1593 G TRAP-type C4-dicarboxylate transport system, large permease component
579 1026 COG1621 G Sucrose-6-phosphate hydrolase SacC, GH32 family
297 369 COG1626 G Neutral trehalase
180 188 COG1635 G H Thiazole synthase/Archaeal ribulose 1,5-bisphosphate synthetase
922 4681 COG1638 G TRAP-type C4-dicarboxylate transport system, periplasmic component
1029 1175 COG1640 G 4-alpha-glucanotransferase
1408 10853 COG1653 G ABC-type glycerol-3-phosphate transport system, periplasmic component
1306 2045 COG1682 G ABC-type polysaccharide/teichoic acid/polyol phosphate export permease
102 111 COG1751 T G Ligand-binding PK_C domain of pyruvate kinase and diadenylate cyclases
1291 3161 COG1762 T G Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
755 813 COG1803 G Methylglyoxal synthase
806 1640 COG1819 G UDP:flavonoid glycosyltransferase YjiC, YdhE family
1171 1473 COG1820 G N-acetylglucosamine-6-phosphate deacetylase
766 1043 COG1830 G Fructose-bisphosphate aldolase class Ia, DhnA family
1249 2657 COG1840 G H ABC-type transport systems for B6 and hexose phosphate, periplasmic component
545 702 COG1850 G Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein
368 398 COG1869 G D-ribose pyranose/furanose isomerase RbsD
538 1165 COG1874 G Beta-galactosidase GanA
731 784 COG1877 G Trehalose-6-phosphate phosphatase
1151 5574 COG1879 G ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain
78 79 COG1892 G Phosphoenolpyruvate carboxylase
601 688 COG1904 G Glucuronate isomerase
1541 2689 COG1925 T G HPr or related phosphotransfer protein
844 1021 COG1929 G Glycerate kinase
1738 6428 COG1940 K G Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain
147 151 COG1980 G Archaeal fructose 1,6-bisphosphatase
1269 2208 COG2017 G Galactose mutarotase or related enzyme
71 81 COG2074 G I 2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase
663 1162 COG2079 G 2-methylcitrate dehydratase PrpD
661 697 COG2115 G Xylose isomerase
1138 2829 COG2120 G N-acetylglucosaminyl deacetylase, LmbE family
1248 4292 COG2133 G Glucose/arabinose dehydrogenase, beta-propeller fold
358 462 COG2140 G Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily
412 734 COG2152 G Predicted glycosyl hydrolase, GH43/DUF377 family
1091 2826 COG2159 G 5-carboxyvanillate decarboxylase LigW (lignin degradation), amidohydro domain
418 497 COG2160 G L-arabinose isomerase
569 894 COG2182 G Maltose-binding periplasmic protein MalE
582 1352 COG2190 G Phosphotransferase system IIA component
1148 2967 COG2211 G Na+/melibiose symporter or related transporter
275 338 COG2213 G Phosphotransferase system, mannitol-specific IIBC component
1662 3440 COG2220 G L-ascorbate lactonase UlaG, metallo-beta-lactamase superfamily
1523 6103 COG2271 G Sugar phosphate permease
568 1213 COG2273 G Beta-glucanase, GH16 family
993 1920 COG2301 G Citrate lyase beta subunit
93 108 COG2342 G Endo alpha-1,4 polygalactosaminidase, GH114 family (was erroneously annotated as Cys-tRNA synthetase)
616 1521 COG2376 G Dihydroxyacetone kinase
657 722 COG2379 G Glycerate-2-kinase
329 473 COG2407 G L-fucose isomerase or related protein
919 1514 COG2513 G 2-Methylisocitrate lyase and related enzymes, PEP mutase family
832 1559 COG2610 G H+/gluconate symporter GntT or related permease, GntP/DsdX family
213 354 COG2704 G Anaerobic C4-dicarboxylate transporter
701 1016 COG2706 G 6-phosphogluconolactonase, cycloisomerase 2 family
679 1130 COG2721 G Altronate dehydratase
905 2327 COG2723 G Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase
510 1055 COG2730 G Aryl-phospho-beta-D-glucosidase BglC, GH1 family
324 460 COG2731 G N-acetylneuraminate anomerase NanQ, YhcH/YjgK/YiaL family
2149 26165 COG2814 G Predicted arabinose efflux permease AraJ, MFS family
546 592 COG2861 G Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family
815 1256 COG2893 G Phosphotransferase system, mannose/fructose-specific component IIA
573 762 COG2942 G Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family
374 427 COG2943 M G Membrane glycosyltransferase
728 997 COG2971 G BadF-type ATPase, related to human N-acetylglucosamine kinase
699 761 COG3001 G Fructosamine-3-kinase
357 398 COG3010 G Putative N-acetylmannosamine-6-phosphate epimerase
267 423 COG3037 G Ascorbate-specific PTS system IIC component UlaA
859 3706 COG3090 G TRAP-type C4-dicarboxylate transport system, small permease component YiaM
271 407 COG3179 G Chitinase, GH19 family
878 3105 COG3250 G Beta-galactosidase/beta-glucuronidase
630 719 COG3265 G Gluconate kinase
473 484 COG3280 G Maltooligosyltrehalose synthase
436 472 COG3281 G Predicted trehalose synthase
375 772 COG3325 G Chitinase, GH18 family
565 1042 COG3345 G Alpha-galactosidase
424 514 COG3347 G Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase
1018 2696 COG3386 G Sugar lactone lactonase YvrE
834 1442 COG3387 G Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family
468 561 COG3394 G Chitooligosaccharide deacetylase ChbG, YdjC/CelG family
547 823 COG3395 G D-threonate/D-erythronate kinase OtnK and related C4-acid sugar kinases, YgbK/DUF1537 family
327 398 COG3405 G Endo-1,4-beta-D-glucanase Y
770 1339 COG3408 G Glycogen debranching enzyme (alpha-1,6-glucosidase)
341 728 COG3414 G Phosphotransferase system, galactitol-specific IIB component
325 328 COG3429 G Glucose-6-phosphate dehydrogenase assembly protein OpcA, contains a peptidoglycan-binding domain
305 747 COG3444 G Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB
463 637 COG3459 G Cellobiose phosphorylase
136 230 COG3469 G Chitinase
540 2186 COG3507 G Beta-xylosidase
575 1089 COG3509 G Acetyl xylan esterase AxeA and related esterases, LpqC family
578 1247 COG3525 G N-acetyl-beta-hexosaminidase
361 761 COG3533 G Beta-L-arabinofuranosidase, GH127 family
410 860 COG3534 G Alpha-L-arabinofuranosidase
301 983 COG3537 G Putative alpha-1,2-mannosidase
385 401 COG3588 G Fructose-bisphosphate aldolase class 1
300 367 COG3594 G Fucose 4-O-acetylase or related acetyltransferase
640 892 COG3622 G Hydroxypyruvate/dehydroerythronate isomerase, Hyi/OtnI family
137 161 COG3623 G L-ribulose-5-phosphate 3-epimerase UlaE
375 459 COG3635 G 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type
189 198 COG3661 G Alpha-glucuronidase
221 287 COG3664 G Beta-xylosidase
342 1097 COG3669 G Alpha-L-fucosidase
152 176 COG3684 G P Tagatose-1,6-bisphosphate/sulfofructosephosphate aldolase
422 915 COG3693 G Endo-1,4-beta-xylanase, GH35 family
245 256 COG3709 G Ribose 1,5-bisphosphate kinase PhnN
285 692 COG3715 G Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component
307 713 COG3716 G Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IID component
375 420 COG3717 G 5-keto 4-deoxyuronate isomerase
379 421 COG3718 G 5-deoxy-D-glucuronate isomerase
118 143 COG3730 G Phosphotransferase system sorbitol-specific IIC component
143 184 COG3731 G Phosphotransferase system sorbitol-specific IIA component
121 154 COG3732 G Phosphotransferase system sorbitol-specific IIB component
319 364 COG3734 G 2-keto-3-deoxy-galactonokinase
208 211 COG3769 G Mannosyl-3-phosphoglycerate phosphatase YedP/MpgP, HAD superfamily
164 279 COG3775 G Phosphotransferase system, galactitol-specific IIC component
183 200 COG3822 G D-lyxose ketol-isomerase
438 534 COG3833 G ABC-type maltose transport system, permease component MalG
652 1171 COG3836 G 2-keto-3-deoxy-L-rhamnonate aldolase RhmA
1469 5232 COG3839 G ABC-type sugar transport system, ATPase component MalK
204 208 COG3855 G Fructose-1,6-bisphosphatase
224 484 COG3866 G Pectate lyase
191 252 COG3867 G Arabinogalactan endo-1,4-beta-galactosidase
166 199 COG3868 G Alpha-1,4 polygalactosaminidase, glycosyl hydrolase family GH114
192 197 COG3892 G Myo-inositol catabolism protein LolC
69 69 COG3925 T G N-terminal domain of the PTS fructose-specific IIB component
212 257 COG3934 G Endo-1,4-beta-mannosidase
28 32 COG3936 G Membrane-bound acyltransferase YfiQ, involved in biofilm formation
225 363 COG3940 G Beta-xylosidase, GH43 family
312 339 COG3954 G Phosphoribulokinase
519 671 COG3957 G Phosphoketolase
849 1156 COG3958 G Transketolase, C-terminal subunit
850 1152 COG3959 G Transketolase, N-terminal subunit
245 280 COG3961 G H R TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase
356 377 COG3962 G TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism
268 655 COG3979 G Chitodextrinase
356 397 COG4095 G Sugar transporter, SemiSWEET family, contains PQ motif
303 520 COG4124 G Beta-mannanase
58 60 COG4130 G Predicted sugar epimerase, xylose isomerase-like family
270 318 COG4154 G L-fucose mutarotase/ribose pyranase, RbsD/FucU family
151 197 COG4193 G Beta- N-acetylglucosaminidase
219 803 COG4209 G ABC-type polysaccharide transport system, permease component
157 163 COG4211 G ABC-type glucose/galactose transport system, permease component
518 846 COG4213 G ABC-type xylose transport system, periplasmic component
506 744 COG4214 G ABC-type xylose transport system, permease component
325 719 COG4225 G Rhamnogalacturonyl hydrolase YesR
203 238 COG4284 G UDP-N-acetylglucosamine pyrophosphorylase
157 212 COG4354 G Beta-glucosidase, glycosyl-hydrolase family 116
182 331 COG4409 M G Neuraminidase (sialidase) NanH, contains C-terminal autotransporter domain
219 365 COG4451 G Ribulose bisphosphate carboxylase small subunit
196 203 COG4468 G Galactose-1-phosphate uridylyltransferase
167 187 COG4573 G Tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ
163 304 COG4580 G Maltoporin (phage lambda and maltose receptor)
454 695 COG4632 G Sugar-P-sugar glycosidase (uncovering enzyme, UCE), NAGPA superfamily
379 595 COG4668 G Mannitol/fructose-specific phosphotransferase system, IIA domain
216 355 COG4677 G I Pectin methylesterase and related acyl-CoA thioesterases
228 348 COG4692 M G Predicted neuraminidase (sialidase)
50 67 COG4724 G Endo-beta-N-acetylglucosaminidase D
183 187 COG4806 G L-rhamnose isomerase
62 76 COG4809 G ADP-dependent glucokinase/phosphofructokinase
199 247 COG4813 G Trehalose utilization protein
120 196 COG4833 G Predicted alpha-1,6-mannanase, GH76 family
73 100 COG4945 T G Carbohydrate-binding DOMON domain
96 140 COG4975 G Glucose uptake protein GlcU
500 1286 COG4993 G Glucose dehydrogenase, PQQ-dependent
136 144 COG5017 G UDP-N-acetylglucosamine transferase subunit ALG13
48 49 COG5026 G Hexokinase
104 120 COG5039 M G Exopolysaccharide biosynthesis protein EpsI, predicted pyruvyl transferase
87 540 COG5263 G Glucan-binding domain (YG repeat)
154 617 COG5297 G Cellulase/cellobiase CelA1
148 259 COG5309 G Exo-beta-1,3-glucanase, GH17 family
238 336 COG5368 G Endo-beta-1,2-glucanase, glucoamylase superfamily
406 957 COG5434 G Polygalacturonase
105 120 COG5498 G Endoglucanase Acf2
22 23 COG5521 G Maltodextrin utilization protein YvdJ (function unknown)
94 114 COG5542 G Mannosyltransferase related to Gpi18