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E - Amino acid transport and metabolism

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COG
definitions
Organims Proteins Median Protein
Length
Genes
296 2,296 548,436 355.0 291
Organism Protein COG Cat Annotation
1867 1963 COG0002 E N-acetyl-gamma-glutamylphosphate reductase
2212 5182 COG0006 E Xaa-Pro aminopeptidase
1505 3089 COG0010 E Arginase/agmatinase family enzyme
1721 1828 COG0014 E Gamma-glutamyl phosphate reductase
2035 3495 COG0019 E Diaminopimelate decarboxylase
1982 5801 COG0028 E H Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme
2072 4586 COG0031 E Cysteine synthase
1899 1933 COG0040 E ATP phosphoribosyltransferase
1880 1948 COG0059 E H Ketol-acid reductoisomerase
1890 2368 COG0065 E Homoaconitase/3-isopropylmalate dehydratase large subunit
1897 2357 COG0066 E 3-isopropylmalate dehydratase small subunit
1679 1921 COG0067 E Glutamate synthase domain 1
1796 2827 COG0069 E Glutamate synthase domain 2
1682 1948 COG0070 E Glutamate synthase domain 3
1305 1976 COG0075 E F Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG
1030 1737 COG0076 E Glutamate or tyrosine decarboxylase or a related PLP-dependent protein
1944 2041 COG0077 E Prephenate dehydratase (decarboxylase)
2051 2401 COG0078 E Ornithine carbamoyltransferase
2028 4212 COG0079 E Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase
2070 2095 COG0082 E Chorismate synthase
1099 1111 COG0083 E Homoserine kinase
1906 1954 COG0106 E Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
1921 2097 COG0107 E Imidazole glycerol phosphate synthase subunit HisF
2204 2581 COG0112 E Glycine/serine hydroxymethyltransferase
2080 4994 COG0115 E H Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
1903 2037 COG0118 E Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH
1983 5327 COG0119 E Isopropylmalate/homocitrate/citramalate synthases
2084 2173 COG0128 E 5-enolpyruvylshikimate-3-phosphate synthase
1889 3509 COG0129 G E Dihydroxyacid dehydratase/phosphogluconate dehydratase
1897 1904 COG0131 E Imidazoleglycerol phosphate dehydratase HisB
1895 2143 COG0133 E Tryptophan synthase beta chain
1881 1960 COG0134 E Indole-3-glycerol phosphate synthase
1708 1843 COG0135 E Phosphoribosylanthranilate isomerase
2124 2392 COG0136 E Aspartate-semialdehyde dehydrogenase
1934 1975 COG0137 E Argininosuccinate synthase
1898 1954 COG0139 E Phosphoribosyl-AMP cyclohydrolase
1744 1780 COG0140 E Phosphoribosyl-ATP pyrophosphohydrolase
1890 2158 COG0141 E Histidinol dehydrogenase
952 1919 COG0145 E Q N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit
763 1412 COG0146 E Q N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit
1952 3587 COG0147 E H Anthranilate/para-aminobenzoate synthases component I
1893 1962 COG0159 E Tryptophan synthase alpha chain
1184 2353 COG0160 E Acetylornithine aminotransferase/4-aminobutyrate aminotransferase/amino acid racemase
1946 2131 COG0165 E Argininosuccinate lyase
2090 2688 COG0169 E Shikimate 5-dehydrogenase
1950 3906 COG0174 E Glutamine synthetase
1567 3112 COG0175 E H Phosphoadenylyl sulfate (PAPS) reductase/FAD synthetase or related enzyme
1726 4518 COG0179 C E Oxaloacetate decarboxylase and tautomerase, fumarylacetoacetate (FAA) hydrolase family
971 1021 COG0182 E 5-methylthioribose/5-deoxyribulose 1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit
1653 3725 COG0189 J E H Q Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily
1584 3105 COG0235 G E 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation)
1116 1433 COG0241 E Histidinol phosphatase/D-glycero-mannoheptose bisphosphatephosphatase, HAD superfamily
1377 1712 COG0252 J E L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
1916 2016 COG0253 E Diaminopimelate epimerase
1544 2260 COG0260 E Leucyl aminopeptidase
1729 1814 COG0263 E Glutamate 5-kinase
1926 2020 COG0287 E Prephenate dehydrogenase
2018 2110 COG0289 E 4-hydroxy-tetrahydrodipicolinate reductase
1522 3380 COG0308 E Aminopeptidase N, contains DUF3458 domain
2114 5113 COG0329 M E 4-hydroxy-tetrahydrodipicolinate synthase/N-acetylneuraminate lyase
1714 2917 COG0334 E Glutamate dehydrogenase/leucine dehydrogenase
1923 2153 COG0337 E 3-dehydroquinate synthetase
1957 2330 COG0345 E Pyrroline-5-carboxylate reductase
1589 3122 COG0347 T E Nitrogen regulatory protein PII
1498 3061 COG0367 E Asparagine synthetase B (glutamine-hydrolyzing)
1642 1720 COG0403 E Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
1709 3251 COG0404 E Glycine cleavage system protein T (aminomethyltransferase)
1319 2522 COG0405 E Gamma-glutamyltranspeptidase
1302 5352 COG0410 E ABC-type branched-chain amino acid transport system, ATPase component LivF
1218 4730 COG0411 E ABC-type branched-chain amino acid transport system, ATPase component LivG
1433 2372 COG0421 E Spermidine synthase (polyamine aminopropyltransferase)
2171 8567 COG0436 E Aspartate/methionine/tyrosine aminotransferase
1791 1972 COG0440 E Acetolactate synthase, small subunit
1474 8271 COG0444 E P ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
2043 2721 COG0458 E F Carbamoylphosphate synthase large subunit
1996 2377 COG0460 E Homoserine dehydrogenase
2207 2705 COG0462 E F Phosphoribosylpyrophosphate synthetase
1959 3178 COG0473 C E Isocitrate/isopropylmalate dehydrogenase
921 2727 COG0477 G E P R MFS family permease, includes anhydromuropeptide permease AmpG
1785 4092 COG0493 E R NADPH-dependent glutamate synthase beta chain or related oxidoreductase
2017 2877 COG0498 E Threonine synthase
2021 2150 COG0505 E F Carbamoylphosphate synthase small subunit
1366 1529 COG0506 E Proline dehydrogenase
1784 2127 COG0509 E Glycine cleavage system protein H (lipoate-binding)
1937 2515 COG0512 E H Anthranilate/para-aminobenzoate synthase component II (glutamine amidotransferase)
1975 4165 COG0520 E Selenocysteine lyase/Cysteine desulfurase
2123 3291 COG0527 E Aspartate kinase
1744 6740 COG0531 E Serine and glutamate transporter AimA/YbeC, amino acid:H+ symporter family
1876 2364 COG0547 E Anthranilate phosphoribosyltransferase, glycosyltransferase domain
1852 2346 COG0548 E N-acetylglutamate kinase
528 654 COG0549 E Carbamate kinase
1294 5369 COG0559 E Branched-chain amino acid ABC-type transport system, permease component
1634 3097 COG0560 E Phosphoserine phosphatase
1631 4345 COG0591 E Na+/proline symporter
1824 8433 COG0601 E P ABC-type dipeptide/oligopeptide/nickel transport system, permease component
1209 1826 COG0620 E Methionine synthase II (cobalamin-independent)
2041 8039 COG0624 E Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase
1672 3841 COG0626 E Cystathionine beta-lyase/cystathionine gamma-synthase
1573 1854 COG0646 E Methionine synthase I (cobalamin-dependent), methyltransferase domain
1772 8507 COG0665 E Glycine/D-amino acid oxidase (deaminating)
1617 8468 COG0683 E ABC-type branched-chain amino acid transport system, periplasmic component
1801 2274 COG0685 E 5,10-methylenetetrahydrofolate reductase
1257 1687 COG0686 E Alanine dehydrogenase (includes sporulation protein SpoVN)
1165 3073 COG0687 E Spermidine/putrescine-binding periplasmic protein
2098 15043 COG0697 E R Amino acid export permease, drug/metabolite transporter (DMT) superfamily
1964 2382 COG0703 E Shikimate kinase
839 866 COG0709 E Selenophosphate synthase
502 531 COG0710 E 3-dehydroquinate dehydratase, type I
769 1130 COG0722 E 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
1802 9335 COG0747 E ABC-type transport system, periplasmic component
356 410 COG0754 E Glutathionylspermidine synthase, CHAP domain
1620 1754 COG0757 E 3-dehydroquinate dehydratase, type II
1444 6677 COG0765 E ABC-type amino acid transport system, permease component
404 515 COG0786 E Na+/glutamate symporter
672 726 COG0804 E Urease alpha subunit
258 709 COG0814 E Amino acid permease
678 736 COG0831 E Urease gamma subunit
665 721 COG0832 E Urease beta subunit
320 475 COG0833 E Amino acid permease
1776 11730 COG0834 T E ABC-type amino acid transport/signal transduction system, periplasmic component/domain
1642 1723 COG1003 E Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
680 777 COG1027 E Aspartate ammonia-lyase
1834 2852 COG1045 E Serine acetyltransferase
1667 5767 COG1063 E R Threonine dehydrogenase or related Zn-dependent dehydrogenase
2008 3389 COG1104 E Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family
489 1355 COG1113 E L-asparagine transporter or related permease
472 660 COG1114 E Branched-chain amino acid permease
1070 1943 COG1115 E Na+/alanine symporter
464 690 COG1124 E P ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
777 995 COG1125 E ABC-type proline/glycine betaine transport system, ATPase component
1467 4710 COG1126 E ABC-type polar amino acid transport system, ATPase component
1041 1495 COG1135 E ABC-type methionine transport system, ATPase component
1054 1671 COG1164 E Oligoendopeptidase F
676 690 COG1166 E Arginine decarboxylase (spermidine biosynthesis)
1484 4775 COG1167 K E DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain
853 1084 COG1168 E R Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
1729 3275 COG1171 E Threonine deaminase
1810 8378 COG1173 E P ABC-type dipeptide/oligopeptide/nickel transport system, permease component
811 1654 COG1174 E ABC-type proline/glycine betaine transport system, permease component
1118 2718 COG1176 E ABC-type spermidine/putrescine transport system, permease component I
1161 3058 COG1177 E ABC-type spermidine/putrescine transport system, permease component II
637 1050 COG1231 E Monoamine oxidase
1725 4061 COG1246 E N-acetylglutamate synthase or related acetyltransferase, GNAT family
1681 5126 COG1247 E L-amino acid N-acyltransferase MnaT
640 687 COG1279 E Arginine exporter protein ArgO
1421 4925 COG1280 E Threonine/homoserine/homoserine lactone efflux protein
1098 1414 COG1296 E Predicted branched-chain amino acid permease (azaleucine resistance)
434 463 COG1350 E Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)
546 667 COG1362 E Aspartyl aminopeptidase
945 1663 COG1363 G E Putative aminopeptidase FrvX
1423 1450 COG1364 E Bifunctional glutamate N-acetyltransferase (ornithine transacetylase) ArgJ
1103 1920 COG1387 E R Histidinol phosphatase or related hydrolase of the PHP family
1549 1896 COG1410 E Methionine synthase I, cobalamin-binding domain
720 925 COG1446 E Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily
585 755 COG1448 E Aspartate/aromatic aminotransferase
187 192 COG1465 E 3-dehydroquinate synthase, class II
633 763 COG1505 E Prolyl endopeptidase PreP, S9A serine peptidase family
1679 7282 COG1506 E Dipeptidyl aminopeptidase/acylaminoacyl peptidase
875 998 COG1540 E 5-oxoprolinase subunit A
871 993 COG1586 E S-adenosylmethionine decarboxylase
1871 2444 COG1605 E Chorismate mutase
142 142 COG1685 E Archaeal shikimate kinase
189 196 COG1687 E Branched-chain amino acid transport protein AzlD
259 292 COG1712 E L-aspartate dehydrogenase, NAD(P)-dependent
963 1256 COG1748 E Saccharopine dehydrogenase, NADP-dependent
1301 1879 COG1760 E L-serine deaminase
673 763 COG1770 E Protease II
306 710 COG1775 E Q Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB
287 297 COG1791 E Acireductone dioxygenase (methionine salvage), cupin superfamily
255 269 COG1823 E L-cystine transporter TcyP, sodium:dicarboxylate symporter family
627 833 COG1834 E N-Dimethylarginine dimethylaminohydrolase
1085 1839 COG1878 E Kynurenine formamidase
620 629 COG1897 E Homoserine O-succinyltransferase
205 243 COG1900 E Sulfur incorporation enzyme MA1821 (anaerobic homocysteine biosynthesis), HcyBio/DUF39 family
1132 1885 COG1914 E P Mn2+, Fe2+, or oxoproline transporter MntH/PxpG, NRAMP family
1487 1548 COG1932 E H Phosphoserine aminotransferase
237 250 COG1945 E Pyruvoyl-dependent arginine decarboxylase
899 1077 COG1966 C E Carbon starvation protein CstA (peptide/pyruvate transporter)
797 1183 COG1982 E Arginine/lysine/ornithine decarboxylase
939 1181 COG1984 E 5-oxoprolinase subunit C/Allophanate hydrolase subunit 2
1262 1479 COG2008 E Threonine aldolase
886 1246 COG2011 E ABC-type methionine transport system, permease component
1126 1344 COG2021 E Homoserine O-acetyltransferase
341 382 COG2040 E Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
957 1217 COG2049 E 5-oxoprolinase subunit B/Allophanate hydrolase subunit 1
205 225 COG2056 E Predicted histidine transporter YuiF, NhaC family
651 763 COG2066 E Glutaminase
985 1276 COG2071 E Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain
1207 1781 COG2095 E Small neutral amino acid transporter SnatA, MarC family
806 1003 COG2105 E Predicted gamma-glutamylamine cyclotransferase YtfP, GGCT/AIG2-like family
701 1310 COG2113 E ABC-type proline/glycine betaine transport system, periplasmic component
1492 1547 COG2171 E Tetrahydrodipicolinate N-succinyltransferase
951 1614 COG2195 E Di- or tripeptidase
164 167 COG2232 E Pyrrolysine biosynthesis ligase PylC and related enzymes, ATP-grasp superfamily
996 3054 COG2234 O E Zn-dependent amino- or carboxypeptidase, M28 family
453 519 COG2235 E Arginine deiminase
770 1296 COG2309 E Leucyl aminopeptidase (aminopeptidase T)
980 1494 COG2355 O E Zn-dependent dipeptidase, microsomal dipeptidase homolog
263 317 COG2362 E D-aminopeptidase
837 1560 COG2423 E Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family
280 295 COG2431 E Lysine export protein LysO/YbjE, DUF340 family
292 296 COG2502 E Asparagine synthetase A
680 809 COG2515 E 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family
423 506 COG2716 E Glycine cleavage system regulator GcvR
1353 1897 COG2873 E O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent
925 1275 COG2876 E 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
571 619 COG2902 E NAD-specific glutamate dehydrogenase
316 409 COG2939 E Carboxypeptidase C (cathepsin A)
685 783 COG2957 E Agmatine/peptidylarginine deiminase
650 653 COG2981 E P Sulfate transporter CysZ
969 1300 COG2986 E Histidine ammonia-lyase
896 947 COG2987 E Urocanate hydratase
336 383 COG2988 E Succinylglutamate desuccinylase
293 347 COG3033 E Tryptophanase
196 202 COG3048 E D-serine dehydratase
128 128 COG3060 K E Transcriptional regulator MetJ (met regulon)
202 211 COG3075 E Anaerobic glycerol-3-phosphate dehydrogenase
778 1318 COG3104 E Dipeptide/tripeptide permease
251 342 COG3138 E Arginine/ornithine N-succinyltransferase beta subunit
1097 1597 COG3185 E R 4-hydroxyphenylpyruvate dioxygenase and related hemolysins
391 401 COG3186 E Phenylalanine-4-hydroxylase
668 873 COG3191 E L-aminopeptidase/D-esterase
118 132 COG3192 E Ethanolamine transporter EutH, required for ethanolamine utilization at low pH
628 667 COG3200 E 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II
262 303 COG3232 E 5-carboxymethyl-2-hydroxymuconate isomerase
157 168 COG3283 K E Transcriptional regulator TyrR of aromatic amino acids metabolism
391 594 COG3314 D E Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain
459 562 COG3340 E Peptidase E
373 433 COG3404 E Formiminotetrahydrofolate cyclodeaminase
236 272 COG3457 E Predicted amino acid racemase
513 565 COG3483 E Tryptophan 2,3-dioxygenase (vermilion)
223 321 COG3579 E Aminopeptidase C
699 994 COG3616 E D-serine dehydratase, pyridoxal phosphate-dependent
250 256 COG3633 E Na+/serine and Na+/threonine symporter SstT
225 249 COG3643 E Glutamate formiminotransferase
265 319 COG3681 E L-cysteine desulfidase YhaM
923 923 COG3705 E ATP phosphoribosyltransferase regulatory subunit HisZ
216 221 COG3724 E Succinylarginine dihydrolase
526 724 COG3741 E N-formylglutamate amidohydrolase
88 92 COG3799 E Methylaspartate ammonia-lyase
1742 5375 COG3842 E ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component
585 622 COG3844 E Kynureninase
315 421 COG3931 E Predicted N-formylglutamate amidohydrolase
467 666 COG3938 E Proline racemase/hydroxyproline epimerase
479 530 COG3968 E Glutamine synthetase type III
196 201 COG3977 E Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase
157 157 COG3978 E Acetolactate synthase small subunit, contains ACT domain
9 9 COG4024 E Component of tRNA-dependent cysteine biosynthesis SepCysE, DUF2100 family
281 334 COG4091 E Predicted homoserine dehydrogenase, contains C-terminal SAF domain
442 730 COG4126 E Asp/Glu/hydantoin racemase
344 551 COG4160 E ABC-type arginine/histidine transport system, permease component
99 100 COG4161 E ABC-type arginine transport system, ATPase component
1058 2346 COG4166 E ABC-type oligopeptide transport system, periplasmic component
657 903 COG4175 E ABC-type proline/glycine betaine transport system, ATPase component
653 915 COG4176 E ABC-type proline/glycine betaine transport system, permease component
1291 5332 COG4177 E ABC-type branched-chain amino acid transport system, permease component
127 156 COG4187 E Citrulline hydrolase RocB
366 587 COG4215 E ABC-type arginine transport system, permease component
210 214 COG4229 E Enolase-phosphatase E1 involved in merthionine salvage
619 666 COG4230 E Delta 1-pyrroline-5-carboxylate dehydrogenase
363 386 COG4302 E Ethanolamine ammonia-lyase, small subunit
363 389 COG4303 E Ethanolamine ammonia-lyase, large subunit
275 441 COG4311 E Sarcosine oxidase delta subunit
274 284 COG4336 E 5-oxoproline utilization protein PxpI/YcsI, D-glutamate cyclase/UPF0317 family
205 222 COG4359 E 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase (methionine salvage)
569 640 COG4392 E Branched-chain amino acid transport protein
346 351 COG4401 E Chorismate mutase AroH
130 135 COG4413 E Urea transporter
478 505 COG4448 E L-asparaginase II
262 422 COG4583 E Sarcosine oxidase gamma subunit
406 485 COG4597 E ABC-type amino acid transport system, permease component
274 347 COG4598 E ABC-type histidine transport system, ATPase component
562 857 COG4608 E ABC-type oligopeptide transport system, ATPase component
259 414 COG4690 E Dipeptidase
147 172 COG4766 E Ethanolamine utilization protein EutQ, cupin superfamily (function unknown)
118 156 COG4810 E Ethanolamine utilization protein EutS, microcompartment shell protein
84 99 COG4812 E Ethanolamine utilization protein EutT, cobalamin adenosyltransferase
122 156 COG4816 E Ethanolamine utilization protein EutL, microcompartment shell protein
108 119 COG4819 E Ethanolamine utilization protein EutA, reactivase of ethanolamine ammonia-lyase
112 123 COG4820 E Ethanolamine utilization protein EutJ, possible chaperonin
245 269 COG4857 E 5-Methylthioribose/5-deoxyribose kinase, methionine salvage pathway
112 119 COG4865 E Glutamate mutase epsilon subunit
118 152 COG4917 E Ethanolamine utilization protein EutP, contains a P-loop NTPase domain
1958 3080 COG4992 E Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase
472 618 COG5006 E Threonine/homoserine efflux transporter RhtA, contains EamA domain
116 122 COG5383 E 2-oxoadipate dioxygenase/decarboxylase HglS/YdcJ family
31 31 COG5630 E N-acetylglutamate synthase (arginine biosynthesis)
104 104 COG5834 D E Stage V sporulation protein SpoVAA, subunit of dipicolinate uptake complex
103 103 COG5835 D E Stage V sporulation protein SpoVAB, subunit of dipicolinate uptake complex
237 276 COG5836 D E Stage V sporulation protein SpoVAC, subunit of dipicolinate uptake complex
234 275 COG5837 D E Stage V sporulation protein SpoVAD, subunit of dipicolinate uptake complex
236 271 COG5839 D E Stage V sporulation protein SpoVAEB, subunit of dipicolinate uptake complex
160 205 COG5840 D E Stage V sporulation protein SpoVAF, subunit of dipicolinate uptake complex, GerA superfamily
185 190 COG5842 D E Dipicolinate synthase subunit A (sporulation protein SpoVFA)
188 191 COG5843 D E Dipicolinate synthase subunit B (sporulation protein SpoVFB)
10 10 COG5961 J E O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase