D - Cell cycle control, cell division, chromosome partitioning
Stats
| COG definitions |
Organims | Proteins | Median Protein Length |
Genes |
|---|---|---|---|---|
| 196 | 2,291 | 140,087 | 336.0 | 194 |
| Organism | Protein | COG | Cat | Annotation |
|---|---|---|---|---|
| 2141 | 2448 | COG0206 | D | Cell division GTPase FtsZ |
| 1685 | 1720 | COG0218 | D | GTP-binding protein EngB required for normal cell division |
| 1671 | 2260 | COG0239 | D P | Fluoride ion exporter CrcB/FEX, affects chromosome condensation |
| 1063 | 1673 | COG0455 | D N | MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase |
| 1276 | 2789 | COG0464 | D T M | AAA+-type ATPase, SpoVK/Ycf46/Vps4 family |
| 2112 | 5338 | COG0489 | D | Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family |
| 1551 | 4769 | COG0535 | D H | Radical SAM superfamily maturase, SkfB/NifB/PqqE family |
| 2043 | 2043 | COG0536 | L D | GTPase involved in cell partioning and DNA repair |
| 2024 | 5051 | COG0768 | D M | Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) |
| 2026 | 4359 | COG0772 | D | Peptodoglycan polymerase FtsW/RodA/SpoVE |
| 1584 | 1723 | COG0849 | D | Cell division ATPase FtsA |
| 871 | 893 | COG0850 | D | Septum site-determining protein MinC |
| 734 | 742 | COG0851 | D | Septum formation topological specificity factor MinE |
| 1671 | 2234 | COG1077 | D Z | Cell shape-determining ATPase MreB, actin-like superfamily |
| 2046 | 6235 | COG1192 | D N | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ |
| 2060 | 6180 | COG1196 | D | Chromosome segregation ATPase Smc |
| 741 | 857 | COG1300 | D | Stage II sporulation protein SpoIIM, component of the engulfment complex |
| 1336 | 1608 | COG1426 | D | Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains |
| 2009 | 4763 | COG1475 | D | Chromosome segregation protein Spo0J, contains ParB-like CTPase domain |
| 810 | 885 | COG1485 | D | Cell division protein ZapE (Z ring-associated ATPase), AFG1 superfamily |
| 1966 | 1967 | COG1589 | D | Cell division septal protein FtsQ |
| 563 | 1100 | COG1649 | D | Divisome-localized peptidoglycan glycosyl hydrolase DigH/YddW |
| 1962 | 3170 | COG1674 | D | DNA segregation ATPase FtsK/SpoIIIE or related protein |
| 1351 | 2799 | COG1729 | D | Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction |
| 1663 | 1671 | COG1792 | D Z | Cell shape-determining protein MreC |
| 696 | 762 | COG1799 | D | Cell division protein SepF/YlmF, interacts with FtsZ |
| 369 | 440 | COG2088 | D | DNA-binding protein SpoVG, cell septation regulator |
| 1180 | 2545 | COG2132 | D M P | Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA) |
| 1619 | 1684 | COG2177 | D | Cell division protein FtsX |
| 1077 | 2077 | COG2340 | D R | Spore germination protein YkwD and related proteins with CAP (CSP/antigen 5/PR1) domain |
| 580 | 957 | COG2385 | D M | Sporulation protein SpoIID (lytic transglycosylase) |
| 150 | 151 | COG2450 | D | Predicted archaeal cell division protein, SepF family |
| 572 | 587 | COG2719 | D | Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown) |
| 1761 | 7055 | COG2755 | D I | Lysophospholipase L1 or related esterase. Includes spore coat protein LipC/YcsK |
| 414 | 432 | COG2848 | D | Uncharacterized conserved protein, UPF0210 family |
| 1577 | 1619 | COG2884 | D | Cell division ATPase FtsE |
| 902 | 923 | COG2894 | D | Septum site-determining ATPase MinD |
| 678 | 695 | COG2917 | D | Intracellular septation protein A |
| 1697 | 1718 | COG2919 | D | Cell division protein FtsB |
| 105 | 105 | COG3006 | D | Chromosome condensin MukBEF, kleisin-like MukF subunit |
| 1246 | 1254 | COG3027 | D | Cell division protein ZapA, inhibits GTPase activity of FtsZ |
| 238 | 315 | COG3061 | D | Cell division protein YtfB/OapA (opacity-associated protein A) |
| 213 | 220 | COG3074 | D | Cell division protein ZapB, interacts with FtsZ |
| 975 | 1390 | COG3087 | D | Cell division protein FtsN |
| 102 | 102 | COG3095 | D | Chromosome condensin MukBEF, MukE localization factor |
| 117 | 122 | COG3096 | D | Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB |
| 214 | 214 | COG3105 | D | Membrane-anchored cell division protein YhcB, DUF1043 family |
| 444 | 453 | COG3115 | D | Cell division protein ZipA, interacts with FtsZ |
| 561 | 561 | COG3116 | D | Cell division protein FtsL, interacts with FtsB and FtsQ |
| 725 | 896 | COG3147 | D | Cell division protein DedD (periplasmic protein involved in septation) |
| 412 | 512 | COG3266 | D | Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain |
| 391 | 594 | COG3314 | D E | Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain |
| 664 | 966 | COG3599 | D | Cell division septum initiation protein DivIVA, interacts with FtsZ and MinD |
| 228 | 274 | COG3660 | D | Mitochondrial fission protein ELM1 |
| 526 | 1050 | COG3773 | D M | Cell wall hydrolase CwlJ, involved in spore germination |
| 224 | 229 | COG3827 | D | Cell pole-organizing protein PopZ |
| 342 | 350 | COG3854 | D | Stage III sporulation protein SpoIIIAA |
| 453 | 884 | COG3858 | D | Spore cortex hydrolase SleL/YaaH, N-acetylglucosaminidase of GH18 family |
| 285 | 325 | COG3874 | D | Spore protein YtfJ/GerW, could be involved in germination |
| 157 | 250 | COG4326 | D | Stage 0 sporulation-control protein Spo0M |
| 170 | 174 | COG4477 | D | Septation ring formation regulator EzrA |
| 338 | 339 | COG4582 | D | Cell division protein ZapD, interacts with FtsZ |
| 462 | 858 | COG4641 | D | Spore maturation protein CgeB |
| 487 | 487 | COG4839 | D | Cell division protein FtsL, bacillar variant |
| 1362 | 1798 | COG4942 | D | Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB |
| 97 | 235 | COG5023 | D | Cell shape-controlling protein CetZ, FtsZ-like GTPase |
| 328 | 1086 | COG5184 | D Z | Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins |
| 40 | 50 | COG5185 | D | Chromosome segregation protein NDC80, interacts with SMC proteins |
| 227 | 356 | COG5279 | D | Cytokinesis protein 3, contains TGc (transglutaminase/protease-like) domain |
| 360 | 447 | COG5401 | D | Spore germination protein GerM |
| 150 | 153 | COG5404 | D | Cell division inhibitor SulA, prevents FtsZ ring assembly |
| 252 | 252 | COG5462 | D | Cell division protein FtsL, alphaproteobacterial variant |
| 42 | 131 | COG5491 | D | Archaeal cell division protein CdvB, Snf7/Vps24/ESCRT-III family |
| 252 | 330 | COG5801 | D T | Stage 0 sporulation initiation regulator Spo0A (response regulator, REC-HTH domains) |
| 100 | 99 | COG5802 | D T | Stage 0 sporulation initiation phosphotransferase Spo0B |
| 257 | 406 | COG5803 | D T | Stage 0 sporulation initiation response regulator Spo0F |
| 152 | 437 | COG5804 | D T | Stage 0 sporulation regulatory phosphatase Spo0E |
| 42 | 58 | COG5805 | D T | Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) |
| 47 | 114 | COG5806 | D T | Sporulation sensor histidine kinase B |
| 20 | 20 | COG5807 | D T | Sporulation sensor histidine kinase C |
| 30 | 37 | COG5808 | D T | Sporulation sensor histidine kinase D |
| 1006 | 3435 | COG5809 | D T | Sporulation sensor histidine kinase E |
| 83 | 83 | COG5810 | D T | Sporulation protein KbaA, activator of histidine kinase KinB |
| 238 | 240 | COG5811 | K D | Sporulation sigma factor SigE (mother cell-specific, SpoIIGB) |
| 239 | 246 | COG5812 | K D | Sporulation sigma factor SigF (forespore-specific, SpoIIAC) |
| 235 | 242 | COG5813 | K D | Sporulation sigma factor SigG (forespore-specific, SpoIIIG) |
| 226 | 258 | COG5814 | K D | Sporulation sigma factor SigK (mother cell-specific, SpoIIIC/SpoIVCB) |
| 888 | 1775 | COG5815 | D T | Stage II sporulation protein SpoIIAA (anti-anti-sigma F factor), STAS domain |
| 116 | 120 | COG5816 | D | Stage II sporulation protein SpoIIB (spatial and temporal regulation of the dissolution of septal peptidoglycan during engulfment) |
| 382 | 496 | COG5817 | D | Stage II sporulation protein SpoIIE/SpoIIH (serine phosphatase - sigma-F activation) |
| 233 | 233 | COG5818 | K D O | Stage II sporulation protein SpoIIGA (protease, processing of pro-sigma-E to active sigma-E) |
| 233 | 328 | COG5819 | D | Stage II sporulation protein SpoIIP, required for dissolution of the septal cell wall |
| 100 | 100 | COG5820 | D | Stage II sporulation protein SpoIIQ, required for engulfement |
| 1226 | 2310 | COG5821 | D | Stage II sporulation protein SpoIIQ, clostridial version, metallopeptidase M23 family |
| 222 | 227 | COG5822 | D | Stage II sporulation protein SpoIIR, required for processing of pro-sigma-E |
| 213 | 213 | COG5823 | D | Stage III sporulation protein SpoIIIAB, component of the engulfment complex |
| 227 | 226 | COG5824 | D | Stage III sporulation protein SpoIIIAC, component of the engulfment complex |
| 220 | 219 | COG5825 | D | Stage III sporulation protein SpoIIIAD, component of the engulfment complex |
| 227 | 227 | COG5826 | D | Stage III sporulation protein SpoIIIAE, component of the engulfment complex |
| 204 | 204 | COG5827 | D | Stage III sporulation protein SpoIIIAF, component of the engulfment complex |
| 227 | 227 | COG5828 | D | Stage III sporulation protein SpoIIIAG, component of the engulfment complex |
| 239 | 239 | COG5829 | D | Stage III sporulation protein SpoIIIAH, component of the engulfment complex |
| 229 | 236 | COG5830 | K D | Stage III sporulation protein SpoIIID, transcriptional regulator of sigma-E- and sigma-K-dependent genes |
| 236 | 237 | COG5831 | D | Stage IV sporulation protein SpoIVA, required for spore cortex formation and coat assembly |
| 457 | 523 | COG5832 | D O | Stage IV sporulation protein SpoIVB, serine protease, degrades SpoIIQ, SpoIVFA |
| 137 | 137 | COG5833 | D | Stage IV sporulation protein SpoIVFA, regulates SpoIVFB |
| 104 | 104 | COG5834 | D E | Stage V sporulation protein SpoVAA, subunit of dipicolinate uptake complex |
| 103 | 103 | COG5835 | D E | Stage V sporulation protein SpoVAB, subunit of dipicolinate uptake complex |
| 237 | 276 | COG5836 | D E | Stage V sporulation protein SpoVAC, subunit of dipicolinate uptake complex |
| 234 | 275 | COG5837 | D E | Stage V sporulation protein SpoVAD, subunit of dipicolinate uptake complex |
| 82 | 80 | COG5838 | D | Stage V sporulation protein SpoVAEA, mutants lead to the production of immature spores |
| 236 | 271 | COG5839 | D E | Stage V sporulation protein SpoVAEB, subunit of dipicolinate uptake complex |
| 160 | 205 | COG5840 | D E | Stage V sporulation protein SpoVAF, subunit of dipicolinate uptake complex, GerA superfamily |
| 561 | 1022 | COG5841 | D | Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis |
| 185 | 190 | COG5842 | D E | Dipicolinate synthase subunit A (sporulation protein SpoVFA) |
| 188 | 191 | COG5843 | D E | Dipicolinate synthase subunit B (sporulation protein SpoVFB) |
| 72 | 70 | COG5844 | D | Stage V sporulation protein SpoVM, required for spore cortex and coat synthesis |
| 266 | 600 | COG5845 | K D | Stage V sporulation protein SpoVT, regulator of stationary/sporulation gene expression |
| 482 | 583 | COG5846 | D | Stage VI sporulation protein SpoVID (LysM domain), required for assembly of the spore coat |
| 76 | 88 | COG5847 | D | Stage VI sporulation protein SpoVIF, required for heat resistance |
| 166 | 168 | COG5848 | D T | SigmaK-processing regulatory protein BofA (Bypass-of-forespore protein A) |
| 118 | 118 | COG5849 | D T | SigmaK checkpoint regulator BofC (Bypass-of-forespore protein C) |
| 98 | 191 | COG5850 | K D | Prespore-specific transcriptional regulator RsfA |
| 67 | 133 | COG5851 | L D | Stage 0 sporulation inhibitor Sda, checkpoint for initiation of sporulation and replication |
| 228 | 630 | COG5852 | D | Small acid-soluble spore protein SspA/SspB/SspC/SspD (alpha/beta-type) |
| 63 | 66 | COG5853 | D | Small acid-soluble spore protein SspE (gamma-type) |
| 138 | 141 | COG5854 | D | Small acid-soluble spore protein SspF (alpha/beta-type) |
| 95 | 135 | COG5855 | D | Small acid-soluble spore protein SspH/YfjU |
| 88 | 87 | COG5856 | D | Small acid-soluble spore protein SspI |
| 46 | 44 | COG5857 | D | Small acid-soluble spore protein SspK |
| 31 | 31 | COG5858 | D | Small acid-soluble spore protein SspL |
| 41 | 39 | COG5859 | D | Small acid-soluble spore protein SspN |
| 36 | 36 | COG5860 | D | Small acid-soluble spore protein SspO/CotK |
| 51 | 50 | COG5861 | D | Small acid-soluble spore protein SspP/CotL |
| 21 | 21 | COG5862 | D | Small acid-soluble spore protein CsgA |
| 90 | 90 | COG5863 | D | Small acid-soluble spore protein Tlp (thioredoxin-like protein) |
| 96 | 107 | COG5864 | D | Small acid-soluble spore protein SAS2, clostridial type |
| 110 | 110 | COG5865 | K D | Forespore-specific anti-sigma-G factor CsfB/Gin |
| 133 | 143 | COG5866 | D O | Sporulation-specific protease YabG |
| 91 | 90 | COG5867 | D T | Anti-sigma-F factor Fin |
| 237 | 236 | COG5868 | D | Sporulation protein YabP |
| 195 | 195 | COG5869 | D | Spore cortex formation membrane protein YabQ |
| 41 | 40 | COG5870 | K D | Uncharacterized sporulation protein YbaK, contains DUF2521 domain (not related to E. coli deacylase YbaK, COG2606) |
| 224 | 223 | COG5871 | D | Spore cortex protein YqfC, YabP family |
| 236 | 238 | COG5872 | D | Stage IV sporulation protein YqfD |
| 64 | 63 | COG5873 | D | Sporulation forespore factor SpoIIIL/YqzE |
| 153 | 153 | COG5874 | D | Uncharacterized sporulation protein YtxC |
| 194 | 201 | COG5875 | D | Membrane fission protein FisB/YunB |
| 190 | 239 | COG5878 | D | Uncharacterized sporulation protein YyaC,contains DUF1256 domain |
| 56 | 72 | COG5879 | D | Spore coat protein CotD |
| 96 | 101 | COG5880 | D | Spore coat protein CotE |
| 219 | 381 | COG5881 | D | Spore coat protein CotI/CotS, protein kinase superfamily |
| 59 | 59 | COG5882 | D | Spore coat protein CotJA, required for the assembly of CotJC |
| 172 | 185 | COG5883 | D | Spore coat protein CotJB |
| 98 | 170 | COG5884 | D W | Biofilm matrix protein TasA/Spore protein CotN, contains M73-like domain |
| 37 | 39 | COG5885 | D | Spore coat protein CotO/YjbX |
| 35 | 56 | COG5886 | D | Spore coat protein CotV/CotX (outer spore coat) |
| 27 | 26 | COG5887 | D | Spore coat protein CotW (outer spore coat) |
| 43 | 67 | COG5888 | D | Spore coat protein CotY/CotZ (outer spore coat) |
| 122 | 135 | COG5889 | D | Spore coat protein GerQ/YwdL (inner spore coat) |
| 201 | 241 | COG5890 | D | Uncharacterized sporulation proteins YjcM and YhbB, contain C-terminal amidase domain |
| 225 | 517 | COG5891 | D | Spore coat protein YheC/YheD, ATP-grasp superfamily |
| 58 | 58 | COG5892 | D | Spore coat protein YlbD, FlgN family |
| 64 | 69 | COG5894 | D | Spore coat protein YppG |
| 23 | 23 | COG5895 | D | Uncharacterized sporulation protein YpzA, contains DUF2564 domain |
| 51 | 90 | COG5896 | D | Spore coat protein YraE/YraG |
| 79 | 81 | COG5897 | D | Spore coat protein YsxE, aminoglycoside phosphotransferase family |
| 36 | 37 | COG5898 | D | Spore coat protein YuzC (inner spore coat) |
| 25 | 48 | COG5899 | D | Spore coat protein YwqH |
| 105 | 212 | COG5900 | D | Spore coat protein YybI (inner spore coat) |
| 206 | 715 | COG5901 | D | Spore germination receptor GerABC, GerA subunit (L-alanine receptor) |
| 203 | 811 | COG5902 | D | Spore germination receptor GerABC, GerB subunit (amino acid transporter) |
| 205 | 753 | COG5903 | D | Spore germination receptor GerABC, GerC subunit |
| 90 | 91 | COG5904 | D | Spore germination receptor GerD |
| 968 | 2208 | COG5905 | K D | Spore transcriptional regulator GerE (stand-alone HTH domain) |
| 50 | 128 | COG5906 | D | Spore germination protein GerPA/GerPF (inner spore coat) |
| 45 | 45 | COG5907 | D | Spore germination protein GerPB, DUF2539 family (inner spore coat) |
| 48 | 50 | COG5908 | D | Spore germination protein GerPC (inner spore coat) |
| 44 | 44 | COG5909 | D | Spore germination protein GerPD (inner spore coat) |
| 43 | 43 | COG5910 | D | Spore germination protein GerPE (inner spore coat) |
| 234 | 235 | COG5911 | D | Spore germination protease Gpr |
| 135 | 327 | COG5912 | D | Spore cortex protein CoxA (YrbB), YhcN/YlaJ family |
| 162 | 186 | COG5914 | D | Spore germination protein YpeB, HAD superfamily, activates cortex-lytic enzyme SleB |
| 68 | 73 | COG5915 | D | Transglutaminase |
| 53 | 53 | COG5916 | D | Uncharacterized sporulation protein YfkD |
| 53 | 53 | COG5917 | D | Uncharacterized sporulation protein YjbA, contains UPF0736/DUF3603 domain |
| 114 | 146 | COG5918 | D | Uncharacterized sporulation protein YmfJ, contains DUF3243 domain |
| 56 | 67 | COG5919 | D | Uncharacterized sporulation protein YodI |
| 54 | 53 | COG5920 | D | Uncharacterized sporulation protein YqfT, contains DUF2624 domain |
| 134 | 149 | COG5921 | D | Uncharacterized sporulation protein YqfX, contains DUF308 domain |
| 86 | 87 | COG5922 | D | Uncharacterized sporulation protein YqhG |
| 178 | 185 | COG5923 | D | Uncharacterized sporulation membrane protein YrzE, contains DUF3792 domain |
| 167 | 167 | COG5924 | D | Uncharacterized sporulation protein YtfI, contains DUF2953 domain |
| 103 | 102 | COG5925 | D | Uncharacterized sporulation membrane protein YtrH/SpoVIGA |
| 80 | 81 | COG5926 | D | Uncharacterized sporulation protein YtrI |
| 129 | 129 | COG5928 | D | Sporulation protein SpoIIT/YwmB, DUF1779 family |