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Cancer that forms in tissues of one or both testicles. Testicular cancer is most common in young or middle-aged men.

Results: 15

Screening for testicular cancer

Testicular cancer commonly affects men aged between 20 and 35 years. It accounts up to 2% of cancers diagnosed in men, although the lifetime risk of mortality is less than 1%. Screening for testicular cancer is commonly performed by physician, who performs a physical examination, or self‐examination by the patient. However, there is little evidence that documents the accuracy of such examinations. This review identified that no randomised controlled trials have been performed to evaluate the effectiveness of screening for testicular cancer. In the absence of high quality evidence, male patients with an increased risk of developing testicular cancer should be informed of the potential benefits and harms associated with screening.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Testicular Cancer Screening (PDQ®): Patient Version

Expert-reviewed information summary about tests used to detect or screen for testicular cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 19, 2012

Testicular Cancer Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of testicular cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 7, 2016

Cancer-Related Post-traumatic Stress (PDQ®): Patient Version

Expert-reviewed information summary about post-traumatic stress and related symptoms in cancer patients, cancer survivors, and their family members. Assessment and treatment of these symptoms are discussed.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 7, 2015

Lymphedema (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of lymphedema, a condition in which lymph fluid builds up in tissues and causes swelling.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 29, 2015

Grief, Bereavement, and Coping With Loss (PDQ®): Patient Version

Expert-reviewed report about grief, bereavement, and feelings of loss in survivors of someone who has died of cancer. Grief in children is also discussed.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: March 6, 2013

Chemotherapy for adult women diagnosed with a rare type of ovarian cancer of all stages (malignant germ cell cancer of the ovary)

Malignant germ cell cancer of the ovary (type of ovarian cancer) is a very rare type of cancer. Malignant ovarian germ cell cancer is a term used to describe a group of heterogeneous rare tumours affecting the ovaries. These tumours start in the egg (ovum) producing cells of the ovary, whereas the more common epithelial ovarian cancers start in the cells that cover the surface of the ovary. Unlike epithelial ovarian cancers, these tumours are often diagnosed early and a combination of surgery and chemotherapy usually results in favourable long term overall survival. Due to its rarity, this review is based on only one very small RCT and one small retrospective study. The data from these studies were too sparse to adequately assess the effectiveness and safety of chemotherapy after surgery (adjuvant chemotherapy) in the treatment of malignant germ cell ovarian cancer. All comparisons were restricted to single study analyses and this review was only based on 32 women, so it was not adequately powered to detect differences in survival. Adverse effects of treatment and recurrence‐free survival were incompletely documented and QoL was not reported in any of the studies. We did not find any studies that reported specifically on adults as this disease usually afflicts younger people as opposed to the older population, so there were problems in separating data on adults and children in many of the studies. Many of the treatments used were taken from experiences of treating patients with testicular cancer, as they look similar under the microscope and behave similar clinically. Due to the small number of patients with malignant germ cell cancer in the two studies, our review shows that there were no good quality studies assessing the role of chemotherapy in this disease, be it in early or late stages. There was insufficient evidence to conclude that any form of chemotherapy or best supportive care is superior over the other. This review highlights the need for future good quality, well designed studies.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Platinum‐containing regimens for metastatic breast cancer

What is the issue? Metastatic breast cancer occurs when the cancer has spread to areas of the body beyond the breast and nearby lymph nodes. Although metastatic breast cancer is generally not curable, it is widely accepted that women with metastatic disease should receive some form of chemotherapy to help ease the severity of disease symptoms, while hopefully extending survival time. Chemotherapy containing platinum is known to be effective for treating a number of cancer types including lung, testicular, head and neck, bladder and ovarian cancers, but it also known to cause more adverse effects (such as nausea and vomiting, hair loss, anaemia, kidney damage and leukopenia (low white blood cells)) than other chemotherapy options. The two platinum agents most commonly used for treating metastatic breast cancer are carboplatin and cisplatin.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Late Effects of Treatment for Childhood Cancer (PDQ®): Patient Version

Expert-reviewed information summary about the health problems that continue or appear after cancer treatment has ended.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: April 25, 2017

Childhood Extracranial Germ Cell Tumors Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of childhood extracranial germ cell tumors.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: August 12, 2016

Extragonadal Germ Cell Tumors Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of extragonadal germ cell tumors.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 24, 2016

Unusual Cancers of Childhood Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of unusual cancers of childhood such as cancers of the head and neck, chest, abdomen, reproductive system, skin, and others.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: June 23, 2017

Treatment Options for Children With Undescended Testicles: A Review of the Research for Parents and Caregivers

This summary will cover: What it means to have undescended testicles Treatment options for children with undescended testicles What researchers have found about how well the treatments work Possible side effects of the treatments

Comparative Effectiveness Review Summary Guides for Consumers [Internet] - Agency for Healthcare Research and Quality (US).

Version: August 30, 2013

Cannabis and Cannabinoids (PDQ®): Patient Version

Expert-reviewed information summary about the use of Cannabis and cannabinoids in the treatment of cancer-related side effects, such as nausea and vomiting.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: April 13, 2017

Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes

Diethylstilbestrol during pregnancy poses serious long‐term risks for those exposed in the womb and offers no known benefit for mothers and children.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2009

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