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Treats pain, arthritis, ankylosing spondylitis, and bursitis. This medicine is an NSAID.

UsesSide effectsLatest evidence reviewsResearch summaries for consumersBrand names

Results: 8

Single dose oral sulindac for acute postoperative pain in adults

Pain is commonly experienced after surgical procedures. Postoperative pain is a good model to test whether or not drugs are effective painkillers in participants with moderate or severe pain. In this case we could find no studies that tested oral sulindac against placebo. It is possible that the studies were done, but not reported, because they were used only to register sulindac with licensing authorities throughout the world. However, this leaves an important gap in our knowledge, and it means that we cannot be confident about using oral sulindac for acute painful conditions.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Muscle relaxants for pain management in rheumatoid arthritis

This summary of a Cochrane review presents what we know from research about the effect of muscle relaxants on pain in patients with rheumatoid arthritis.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

Colorectal (bowel) cancer is common worldwide but is especially prevalent in industrialised countries. Genes, diet and lifestyle all seem to be important in the development of bowel cancer.

Experimental animals studies and observational studies have suggested that nonsteroidal anti‐inflammatory drugs and aspirin may reduce the development of colorectal cancer and recurrence of adenomas in patients with familial adenomatous polyposis (FAP).

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2008

Aspirin, steroid and non‐steroidal anti‐inflammatory drugs use for treating Alzheimer's disease

Inflammation may play an important role in the development of Alzheimer’s disease. There is also some evidence from community surveys that people receiving anti‐inflammatory drugs for various medical conditions may be less likely to develop Alzheimer's disease. Fourteen studies met our inclusion criteria for this review and none of the exclusion criteria. Aspirin, steroid and non‐steroidal anti‐inflammatory drugs (NSAIDs) (traditional and the selective cyclooxygenase‐2 (COX‐2) inhibitors) showed no significant benefit in the treatment of Alzheimer's disease. Therefore, the use of these drugs cannot be recommended for the treatment of Alzheimer's disease.         

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

Colorectal Cancer Prevention (PDQ®): Patient Version

Expert-reviewed information summary about factors that may influence the risk of developing of colorectal cancer and about research aimed at the prevention of this disease.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: February 8, 2017

Comparing NSAIDs

How do NSAIDs compare in reducing pain?

PubMed Clinical Q&A [Internet] - National Center for Biotechnology Information (US).

Version: May 1, 2011

Comparing single doses of oral analgesics for acute pain in adults after operation

Acute pain is often felt soon after injury. Most people who have surgery have moderate or severe pain afterwards. Painkillers (analgesics) are tested in people with pain, often following the removal of wisdom teeth. In all these studies the participants have to have at least moderate pain in order for there to be a sensitive measure of pain‐relieving properties. The pain is usually treated with painkillers taken by mouth. Results can be applied to other forms of acute pain.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2015

Childhood Soft Tissue Sarcoma Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of childhood soft tissue sarcomas.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 15, 2017

Systematic Reviews in PubMed

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