Home > Search Results

Results: 4

Using the combined vaccine for protection of children against measles, mumps and rubella

Measles, mumps and rubella (MMR) are three very dangerous infectious diseases which cause severe morbidity, disability and death in low‐income countries.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2016

How can you avoid getting chickenpox?

Chickenpox is highly contagious. If you are not vaccinated and have never had chickenpox, contact with someone who has it will almost always lead to infection. Early vaccination and being careful around those who have chickenpox are the most important precautions you can take.Chickenpox is caused by the varicella-zoster virus, which is one of the herpes viruses. The German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute recommends being vaccinated to lower your chances of infection. If you or someone in your family gets chickenpox there are several things you can do to avoid spreading it to others.Most importantly, people who have chickenpox should avoid contact with anyone who hasn’t had it and with people who have a greater risk of developing more severe symptoms. This especially includes people with a weakened immune system, newborn babies, and non-vaccinated adults. The virus can harm unborn children during pregnancy, and can be life-threatening for newborns. Generally speaking, though, chickenpox rarely has any serious consequences in children who are otherwise healthy. But it can be unpleasant.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: April 6, 2017

Varicella and influenza vaccines may reduce morbidity in patients with blood cancers

Viral infections cause significant disease and even death in patients with blood cancers. In the current systematic review of randomized controlled trials (RCTs) we aimed to evaluate the efficacy and safety of viral vaccines in these patients. The pre‐defined primary outcome was incidence of the infection concerned. Secondary outcomes were mortality due to the viral infection, all‐cause mortality, incidence of complications, incidence of severe viral infection, hospitalization rate, in vitro immune response and frequency of adverse effects. Eight RCTs were included. They evaluated heat‐inactivated varicella zoster virus (VZV) vaccine (two trials), influenza vaccines (five trials) and inactivated poliovirus vaccine (one trial). There were no RCTs on other viral vaccines (hepatitis A, hepatitis B, measles, mumps, rubella). Only the two trials on VZV vaccine reported our pre‐defined primary outcome. All trials reported some of the pre‐defined secondary outcomes. We found that inactivated VZV vaccine might reduce the severity of herpes zoster when given before and after stem cell transplant in adults with lymphoma or leukemia. Inactivated influenza vaccine might reduce upper and lower respiratory infections and hospitalization in adults with multiple myeloma who are undergoing chemotherapy, or children with leukemia or lymphoma within two years post‐chemotherapy. However, the quality of evidence is not high. Local adverse effects occur frequently with the vaccines, although serious adverse effects appear uncommon. Further high‐quality RCTs are needed to clarify the benefits and optimal regimens of viral vaccines for patients with blood cancers.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Fever in children: Overview

Many parents start feeling anxious when their child has a hot, flushed face and is running a high fever. Most of the time a harmless viral infection is the cause. But it is still good for parents to know the signs of more serious medical problems and to realize when a doctor is needed.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: November 17, 2016

Systematic Reviews in PubMed

See all (123)...

Systematic Review Methods in PubMed

See all (4)...

Recent Activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...