Home > Search Results

Results: 2

Immunosuppressive agents for treating IgA nephropathy

IgA nephropathy is a common kidney disease that often leads to decreased kidney function and may result ultimately in kidney failure for one‐third of affected people. The cause of IgA nephropathy is not known, although most people with the disease have abnormalities in their immune system. We identified 32 studies enrolling 1781 patients that met our inclusion criteria. This review found that if people with IgA nephropathy receive immunosuppressive drugs, particularly steroids, they may be less likely to develop kidney failure needing dialysis or transplantation. Few studies were available and the harms of therapy are currently not well understood. Larger placebo‐controlled studies are now needed to be certain about the benefits and hazards of steroids on outcomes in IgA nephropathy and to identify which specific patients might benefit most from the treatment.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2015

Non‐immunosuppressive treatment for IgA nephropathy

IgA nephropathy (IgAN) is the most common primary glomerular disease with approximately 30% to 40% of patients progressing to end‐stage kidney disease (ESKD) within 20 years. The most common regimens include immunosuppressive agents, however the risks of long‐term treatment often outweigh the potential benefits. Non‐immunosuppressive options, including fish oils, anticoagulants, antihypertensive agents and tonsillectomy have also been examined but not reviewed systematically.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Systematic Reviews in PubMed

See all (110)...

Recent Activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...