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Varicoceles: Does varicocele treatment improve fertility in men?

Some experts think that varicoceles can affect fertility in men. If men with a palpable varicocele and poor sperm quality have treatment, the chances of their partner becoming pregnant could possibly improve.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: June 1, 2016

Aspiration and sclerotherapy versus hydrocoelectomy for treating hydrocoeles

Hydrocoeles are common cystic scrotal abnormalities, described as a fluid‐filled collection around the testicles. Hydrocoele can be treated with drainage of the fluid along with an injection of a chemical around the testicle to prevent recurrence, or with open surgery. The aim of this review is to compare these two types of treatment. We found four small studies were identified after an extensive literature search. Due to limited information about the design of the studies, and the small number of patients enrolled, the results should be interpreted with caution. Meta‐analysis showed lower rates of recurrence in the surgery group, however there was insufficient evidence to draw a strong conclusion. Postoperative complications such as infection and fever, as well as cost and time to work resumption were less in the aspiration and sclerotherapy group; however the recurrence rate was higher. Cure at short‐term follow‐up was similar between the groups, however there is significant uncertainty in this result which may be as a result of the age of one of the studies and the different agent used compared to the other studies.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2014

High population coverage of DEC‐medicated salt maintained over at least six months in a community is effective at reducing transmission of lymphatic filariasis and can, if maintained over a long enough period, completely interrupt transmission

Filariasis is a parasite infection of threadlike worms, affecting about 120 million people in more than 83 countries. The infection is transmitted by mosquitoes. Larval forms take up to a year to develop into adult worms, which mate and release thousands of microfilariae (mf) into the blood over the course of their lives. Mf are ingested by mosquitoes from the blood of an infected individual, completing the cycle. This infection may lead to severe disability in the form of lymphoedema and eventually elephantiasis of limbs, and hydrocoele. Though most infected people remain asymptomatic, the lymph vessels are often damaged. A drug, diethylcarbamazine (DEC) has been shown to kill mf, but repeated doses are needed before adult worms are killed or sterilized. This review looked at the effectiveness of giving entire communities DEC‐medicated salt. The review of studies found evidence that DEC when given in a low dose over a period of months or years is effective in reducing the prevalence of filariasis in communities, with no recognized adverse events.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2009

Systematic Reviews in PubMed

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