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The current treatment for people suffering from heart disease and heart failure is drugs and, when possible, restoration of the blood supply in the heart (revascularisation) either by opening the arteries with a tiny balloon in a procedure called primary angioplasty (or percutaneous coronary intervention) or by heart surgery (or coronary artery bypass graft). Revascularisation has reduced the death rate associated with these conditions. In some people, heart disease and heart failure symptoms persist even after revascularisation. Recently, bone marrow stem/progenitor cells have been investigated as a new treatment for people with heart disease and heart failure, whether or not they also undergo revascularisation.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Background: Currently the standard treatment for people suffering a heart attack (due to a blockage in the artery supplying blood to the heart) is direct opening of the artery with a tiny balloon in a procedure called primary angioplasty and introduction of a small tube (called a stent) into the artery to keep it open. The use of primary angioplasty and stents to reopen the blocked artery can lead to a 35% reduction in the mortality (death rate) associated with this condition. In recent years, bone marrow stem/progenitor cells have been investigated as a potential treatment. They may prevent the damage to the heart muscle caused by a heart attack, when used in addition to the treatment offered by primary angioplasty and standard medical therapy.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2015

We reviewed the evidence about the effect of antioxidants and other medicines for Friedreich ataxia.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2016

Expert-reviewed information summary about common conditions that produce chest symptoms. The cardiopulmonary syndromes addressed in this summary are cancer-related dyspnea, malignant pleural effusion, pericardial effusion, and superior vena cava syndrome.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: August 31, 2016

In neurological examinations, neurologists carry out tests in order to identify medical conditions affecting the nervous system.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: January 27, 2016

Acute pancreatitis is an inflammation of the pancreas that typically causes very sudden stomach ache.The pain is usually so severe that most people go straight to a doctor. The most common causes are gallstones blocking the opening of the pancreas and excessive alcohol consumption.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: April 22, 2015

In thalassaemia sometimes the body cannot produce enough haemoglobin. Regular blood transfusions can manage this, but may lead to excess iron in the body, which, if not removed, may damage major organs. Iron chelation therapy removes excess iron; one common chelator is deferiprone. Questions exist about whether deferiprone is as good and safe as the most widely‐used iron chelator, desferrioxamine. Desferrioxamine is administered by a needle under the skin or into a vein, and was the standard monotherapy for 20 years.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2013

Expert-reviewed information summary about the treatment of pheochromocytoma and paraganglioma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: August 18, 2017

The treatment of cancer may cause health problems (late effects) for childhood cancer survivors months or years after successful treatment has ended. Get information about the long-term physical, psychological and social effects of treatment for childhood cancer in this expert-reviewed summary.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: April 25, 2017

The signs of a stroke include a sudden and severe headache, paralysis and speech difficulties. These problems are caused when part of the brain doesn’t get enough oxygen. The exact symptoms mostly depend on what part of the brain is affected.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: July 13, 2017

Expert-reviewed information summary about the treatment of childhood vascular tumors.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: April 7, 2017

Expert-reviewed information summary about the treatment of lymphedema, a condition in which lymph fluid builds up in tissues and causes swelling.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 29, 2015

Expert-reviewed information summary about the treatment of adult primary liver cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: October 20, 2016

Expert-reviewed information summary about the treatment of primary CNS lymphoma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: December 21, 2016

Expert-reviewed information summary about the treatment of childhood ependymoma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: September 22, 2017

Expert-reviewed information summary about the treatment of pituitary tumors.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: August 18, 2017

Expert-reviewed information summary about the treatment of non-small cell lung cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: November 9, 2017

The parathyroid glands are four pea-sized organs found in the neck near the thyroid gland. Find out about risk and genetic factors, symptoms, tests to diagnose, prognosis, staging, and treatment for parathyroid cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: August 18, 2017

Expert-reviewed information summary about the treatment of childhood brain stem glioma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: September 22, 2017

In epilepsy, certain areas of the brain or all areas of the brain are overactive, sending too many signals. Some people have their first seizure in childhood, and others have their first seizure in older age.Medication can help to prevent seizures and maintain a good quality of life.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: January 13, 2016

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