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Ankle sprains are one of the most common types of injury. When an ankle is twisted, the ligaments are overstretched. In the worst case, they might tear. Small blood vessels tear too, causing the swelling around the ankle. Read on to find out about first aid measures, the treatment options and what can help to stabilize the joint.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: April 19, 2018

If someone has their leg in a plaster cast or brace and can’t move it for a long period of time, they are at increased risk of deep vein thrombosis. Injections to prevent blood clots are then recommended. In all other cases, getting back on your feet again as soon as possible is enough.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: March 23, 2017

Evidence from randomised controlled trials is not sufficient to determine if compression stockings as the only and initial treatment are effective in managing and treating varicose veins in the early stages. Varicose veins are widened veins that twist and turn and are visible under the skin of the leg. They generally do not cause medical problems although many sufferers seek medical advice. Symptoms that may occur include pain, ankle swelling, tired legs, restless legs, night cramps, heaviness, itching and distress from their cosmetic appearance. Complications such as oedema, pigmentation, inflammation and ulceration can also develop. Compression stockings are often the first line of treatment and come in a variety of lengths, knee length to full tights, and apply different pressures to support the flow of blood in the veins.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: December 9, 2013

Osteosarcoma and malignant fibrous histiocytoma (MFH) of the bone treatment usually involves surgery to remove the tumor. Chemotherapy, radiation therapy, and/or targeted therapy may also be used. Learn more about osteosarcoma and MFH of bone in this expert-reviewed summary.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 7, 2018

The treatment of cancer may cause health problems (late effects) for childhood cancer survivors months or years after successful treatment has ended. Get information about the long-term physical, psychological and social effects of treatment for childhood cancer in this expert-reviewed summary.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 23, 2018

Childhood soft tissue sarcoma treatment options include surgery, radiation therapy, chemotherapy, observation, targeted therapy, immunotherapy and other medications.  Learn more about the diagnosis and treatment of the many types of childhood soft tissue sarcoma in this expert-reviewed summary.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: April 26, 2018

Systematic Reviews in PubMed

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