Home > Search Results

Results: 16

Perampanel (Fycompa) for epilepsy: Overview

Perampanel (trade name: Fycompa) has been approved since July 2012 as an add-on therapy for epileptic seizures in adults and children over the age of 12.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: August 15, 2014

Brivaracetam (Briviact) for epilepsy: Overview

Brivaracetam (trade name: Briviact) has been approved in Germany since January 2016 as an add-on therapy for epileptic seizures in teenagers over the age of 16 and in adults.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: June 1, 2016

Epilepsy: Overview

In epilepsy, certain areas of the brain or all areas of the brain are overactive, sending too many signals. Some people have their first seizure in childhood, and others have their first seizure in older age.Medication can help to prevent seizures and maintain a good quality of life.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: January 13, 2016

Carbamazepine versus valproate monotherapy for epilepsy

No reliable evidence to distinguish between carbamazepine and valproate for partial onset seizures and generalized onset tonic‐clonic seizures.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2009

Epilepsy: What to do if someone has an epileptic seizure

Most people are not sure how to react if someone has an epileptic seizure. The correct response is not that complicated, though. Just a few rules can help you remember what to do.There are different types of epileptic seizures. The best reaction will depend on the type and severity of the seizure as well as the general situation. The main thing is to stay calm and protect the person having the seizure from harm. Most seizures are not dangerous and pass within a few minutes.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: January 13, 2016

Adding lamotrigine for drug‐resistant partial epilepsy

Epilepsy is a disorder in which unexpected electrical discharges from the brain cause seizures. Approximately one‐third of patients with epilepsy continue to have seizures, despite treatment with presently used (older) antiepileptic drugs (AEDs). In addition, the older AEDs have a lot of adverse effects.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2016

Epilepsy in adults: Treatment with medication

Epilepsy medications can prevent seizures. But they do not work in everyone. It is sometimes possible for people to stop taking medication if they haven't had a seizure for several years.An epileptic seizure is caused by hyperactivity in the brain's nerve cells. Anti-epileptic drugs (AEDs) work by lowering this level of activity. Although AEDs do not cure the underlying causes of epilepsy, they can lower the risk of seizures.The medicine is available in the form of tablets, capsules or syrups. Some can also be injected into a vein, given intravenously through a drip (IV infusion), or inserted into the rectum in the form of a suppository. They can have some unpleasant side effects, but are usually well tolerated at low doses. That is why it is important for each individual person to consider whether to have treatment and, if so, what dose of which medication would be suitable.It is impossible to know beforehand whether a particular drug will help. Some people stop having seizures after taking the first medication they try. Other times it can take much longer to find the right treatment. In some cases the drugs do not help, or only help very little.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: January 13, 2016

Vagus nerve stimulation for partial seizures

Epilepsy is a disorder where unexpected electrical discharges from the brain cause seizures. Most seizures can be controlled by a single antiepileptic drug but sometimes seizures do not respond to drugs. Some people require more than one antiepileptic medication to control their seizures, especially if these originate from one area of the brain (partial epilepsy), instead of involving the whole brain.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2015

Drugs assessed by IQWiG: Overview

Since early 2011, the added benefit of most medications containing new active ingredients must be assessed as soon as they enter the market in Germany. The most important results of the IQWiG reviews are summarized here.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: March 22, 2017

Antiepileptic drugs to treat neuropathic pain or fibromyalgia‐ an overview of Cochrane reviews

Neuropathic pain is pain coming from damaged nerves. It is different from pain messages carried along healthy nerves from damaged tissue (eg a fall, cut, or arthritic knee). Neuropathic pain is treated by different medicines than pain from damaged tissue. Medicines such as paracetamol or ibuprofen are probably not effective in neuropathic pain, while medicines that are sometimes used to treat depression or epilepsy can be very effective in some people with neuropathic pain. Our understanding of fibromyalgia (a condition of persistent, widespread pain and tenderness, sleep problems, and fatigue) is lacking, but fibromyalgia can respond to the same medicines as neuropathic pain.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Acne: Overview

Most teenagers will have pimples at some point. Severe acne can be very distressing. But there are a number of things that can help, although patience is usually needed.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: July 28, 2016

Kidney stones: Overview

Kidney stones are very common, especially in people between the ages of 20 and 40. These small, hard deposits form in the renal pelvis and can enter a ureter. Larger stones can be painful and often have to be surgically removed. There are several options for treatment and prevention.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: February 25, 2016

Migraine prevention in adults

The symptoms of migraine attacks can usually be relieved with painkillers or migraine medication. People who have migraines would usually prefer to stop them from happening in the first place, though. Keeping a migraine diary can help identify possible triggers. Preventive treatment can reduce the number of migraine attacks.Most people with migraine have a type known as episodic migraine, where the attacks occur more or less regularly. Fewer than 2% of people with migraine have a different type known as chronic migraine. This is where the migraine headaches occur on 15 or more days per month over a period of three months or more.Migraine attacks are very painful and can have a major impact on quality of life. Many people with migraine would like to do something themselves to prevent attacks from happening in the first place. A number of different preventive measures can be taken. For instance, some people try to avoid possible migraine triggers. Others learn relaxation techniques or try out an endurance sport. Taking preventive medicine every day is another option.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: November 18, 2015

Chronic tinnitus: What helps – and what doesn’t?

Although a wide range of treatments for chronic tinnitus are offered and used, none of them have been proven to reduce the symptoms. Cognitive behavioral therapy can help people cope better with the tinnitus sounds and improve their quality of life.If tinnitus lasts longer than six months, it is considered to be chronic tinnitus. In many cases the cause remains unknown. This makes it harder to treat effectively. A lot of treatments have been tried out and some have been tested in scientific studies. But most of the studies weren't conclusive enough. So more research is needed in order to be able to say whether any treatments can effectively reduce tinnitus sounds.This doesn't mean that you just have to put up with tinnitus. But because all treatments can have side effects, it isn't a good idea to try out every last one of them. It often makes more sense to try to accept the sounds and find a way to keep them from becoming too distressing in everyday life. Cognitive behavioral therapy (CBT) can help people to do this, as research has shown.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: October 20, 2016

Slipped disk: Non-surgical treatment options

Most people with a slipped disk are offered “conservative” treatment, meaning that the treatment does not involve surgery. This mainly involves exercise, relaxation and positioning, painkillers or local anesthetics, and manual and physical therapy.A slipped disk does not always cause symptoms, but it may cause severe back pain. A slipped disk in the lumbar vertebrae can press on the sciatic nerve and cause pain that often extends through one leg and down into the foot. Most people recover from a slipped disk within six weeks without treatment. Until then there a number of treatment options that aim to help relieve the pain and improve mobility.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: October 25, 2013

Mistletoe Extracts (PDQ®): Patient Version

Expert-reviewed information summary about the use of mistletoe extracts as a treatment for people with cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: February 15, 2017

Systematic Reviews in PubMed

See all (95)...

Systematic Review Methods in PubMed

See all (3)...

Recent Activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...