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This review assessed the ability of minimally invasive and noninvasive tests to assess the groin node status in women with squamous cell vulvar cancer. It concluded that sentinel node identification using 99m-Tc is the most promising test. These conclusions appear reliable, but since some details about the analysis and participants were not reported they should be interpreted with caution.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2005

This review found that radio-guided localisation could be the preferred technique to guide surgical resection of non-palpable breast tumours. Methodological flaws and the low quality of the included studies mean that the authors' conclusions may not be reliable and should be interpreted with caution.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2011

In the past 30–50 years, the natural history of urinary tract infection (UTI) in children has changed as a result of the introduction of antibiotics and improvements in health care. This change has contributed to uncertainty about the most appropriate and effective way to diagnose and treat UTI in children and whether or not investigations and follow-up are justified.

NICE Clinical Guidelines - National Collaborating Centre for Women's and Children's Health (UK).

Version: August 2007

Psoriasis is a common, chronic disease, which for many people, is associated with profound functional, psychological and social morbidity and important comorbidities. Effective treatments are available. Some treatments are expensive; all require appropriate monitoring and some may only be accessed in specialist care settings. Evidence indicates that a substantial proportion of people with psoriasis are currently dissatisfied with their treatment.

NICE Clinical Guidelines - National Clinical Guideline Centre (UK).

Version: October 2012

The management of myeloma is complex and challenging. It increasingly involves the use of expensive drugs. The guideline will aim to raise standards nationally while allowing clinical flexibility and defining a common pathway for patients at various stages of their illness, and of different ages and levels of fitness. Although a consistent approach to management is desirable, it needs to reflect the very different groups of patients with myeloma from the fit and suitable for transplant, fairly fit but not suitable for transplant to patients who are extremely frail and/or unwell.

NICE Guideline - National Collaborating Centre for Cancer (UK).

Version: February 2016

Study found that there is limited evidence on the clinical effectiveness and cost-effectiveness of ablative and other minimally invasive therapies for treating people with liver metastases. Results are presented for a number of ablative and minimally invasive therapies, but all studies had methodological shortcomings, few had a comparator group and there were with limited analyses and many uncertainties. There is scope for further research.

Health Technology Assessment - NIHR Journals Library.

Version: January 2014

Systematic Reviews in PubMed

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