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Liver Hemangioma

A benign tumor of the liver.

PubMed Health Glossary
(Source: NIH - National Institute of Diabetes and Digestive and Kidney Diseases and National Library of Medicine)

What works? Research summarized

Evidence reviews

Diagnosis and Management of Infantile Hemangioma [Internet]

To systematically review evidence addressing the diagnosis and management of infantile hemangiomas (IH).

Management of Infantile Hemangioma

Access to early treatment may be critical for a subset of children facing significant impact from infantile hemangioma (IH). This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse effects of pharmacological and surgical therapies for IH. The systematic review included 148 unique studies published from 1982 to June 2015. The full report, listing all studies, is available at www.effectivehealthcare.ahrq.gov/infantile-hemangioma.

No evidence to support or refute elective surgery for benign liver tumours

The most common benign liver tumours include cavernous haemangioma, focal nodular hyperplasia, and hepatic adenoma. The majority of patients are asymptomatic, and no treatment is indicated. The natural history of haemangioma and focal nodular hyperplasia is typically uneventful whereas that of hepatic adenoma can be complicated by life‐threatening conditions, such as rupture and haemorrhage. For these complications or when a definite histologic diagnosis is needed, surgery is advisable. However, in clinical practice there is a wide variation concerning the use of elective surgery (ie, surgery performed before complications have developed). No randomised clinical trials were identified for this systematic review, but 31 case series without a proper control group were retrieved. Accordingly, there is no evidence to support or refute elective surgery for benign liver tumours.

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Summaries for consumers

Propranolol (Hemangiol) for hemangioma in infants: Overview

Propranolol (trade name: Hemangiol) has been approved in Germany since April of 2014 for the treatment of growing hemangiomas in infants aged 5 weeks and older. A hemangioma is a nodule formed by blood vessels.

No evidence to support or refute elective surgery for benign liver tumours

The most common benign liver tumours include cavernous haemangioma, focal nodular hyperplasia, and hepatic adenoma. The majority of patients are asymptomatic, and no treatment is indicated. The natural history of haemangioma and focal nodular hyperplasia is typically uneventful whereas that of hepatic adenoma can be complicated by life‐threatening conditions, such as rupture and haemorrhage. For these complications or when a definite histologic diagnosis is needed, surgery is advisable. However, in clinical practice there is a wide variation concerning the use of elective surgery (ie, surgery performed before complications have developed). No randomised clinical trials were identified for this systematic review, but 31 case series without a proper control group were retrieved. Accordingly, there is no evidence to support or refute elective surgery for benign liver tumours.

Childhood Vascular Tumors Treatment (PDQ®): Patient Version

Childhood vascular tumor treatment depends on the specific type and location, can involve surgery, and may be followed by chemotherapy or radiation. Targeted therapy, immunotherapy, and other medications may be used. Learn more about vascular tumors in this expert-reviewed summary.

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More about Liver Hemangioma

Photo of a child

Also called: Hepatic hemangioma, Hepatic angioma

See Also: Hemangioma

Other terms to know:
Benign, Benign Tumor, Neoplasm (Tumor)

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